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Akademický článek

Design, in silico studies and biological evaluation of novel chalcones tethered triazolo[3,4-a]isoquinoline as EGFR inhibitors targeting resistance in non-small cell lung cancer.

Autor: Abdelaal N; Biotechnology Department, Faculty of Science, Cairo University, Cairo, Egypt., Ragheb MA; Department of Chemistry (Biochemistry Division), Faculty of Science, Cairo University, Giza, 12613, Egypt., Hassaneen HM; Chemistry Department, Faculty of Science, Cairo University, Cairo, Egypt., Elzayat EM; Biotechnology Department, Faculty of Science, Cairo University, Cairo, Egypt. elzayat.emad@yahoo.com.; Zoology Department, Faculty of Science, Cairo University, Cairo, Egypt. elzayat.emad@yahoo.com., Abdelhamid IA; Chemistry Department, Faculty of Science, Cairo University, Cairo, Egypt. ismail_shafy@yahoo.com.

Publikováno v: Scientific reports [Sci Rep] 2024 Nov 04; Vol. 14 (1), pp. 26647. Date of Electronic Publication: 2024 Nov 04.

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Novel thiazole-based cyanoacrylamide derivatives: DNA cleavage, DNA/BSA binding properties and their anticancer behaviour against colon and breast cancer cells.

Autor: Barakat K; Department of Chemistry (Biochemistry Division), Faculty of Science, Cairo University, Giza, 12613, Egypt., Ragheb MA; Department of Chemistry (Biochemistry Division), Faculty of Science, Cairo University, Giza, 12613, Egypt. mattia@cu.edu.eg., Soliman MH; Department of Chemistry (Biochemistry Division), Faculty of Science, Cairo University, Giza, 12613, Egypt., Abdelmoniem AM; Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt., Abdelhamid IA; Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt. ismail_shafy@cu.edu.eg.

Publikováno v: BMC chemistry [BMC Chem] 2024 Sep 20; Vol. 18 (1), pp. 183. Date of Electronic Publication: 2024 Sep 20.

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In vivo cardioprotective effect of zinc oxide nanoparticles against doxorubicin-induced myocardial infarction by enhancing the antioxidant system and nitric oxide production.

Autor: Mohamed ATAE; Chemistry Department (Biochemistry Division), Faculty of Science, Cairo University, Egypt. Electronic address: aliaatarek1602_sd@psas.bsu.edu.eg., Ragheb MA; Chemistry Department (Biochemistry Division), Faculty of Science, Cairo University, Egypt. Electronic address: mattia@cu.edu.eg., Shehata MR; Chemistry Department, Faculty of Sciences, Cairo University, Egypt. Electronic address: mrshehata@sci.cu.edu.eg., Mohamed AS; Zoology Department, Faculty of Science, Cairo University, Egypt. Electronic address: ayman81125@cu.edu.eg.

Publikováno v: Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) [J Trace Elem Med Biol] 2024 Aug 30; Vol. 86, pp. 127516. Date of Electronic Publication: 2024 Aug 30.

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Akademický článek

Novel hybrid thiazoles, bis-thiazoles linked to azo-sulfamethoxazole: Synthesis, docking, and antimicrobial activity.

Autor: Salem ME; Department of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University(IMSIU), P.O. Box, 90950, Riyadh, 11623, Saudi Arabia.; Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt., Abdelhamid IA; Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt., Elwahy AHM; Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt., Ragheb MA; Department of Chemistry (Biochemistry Division), Faculty of Science, Cairo University, Giza, 12613, Egypt., Alqahtani AS; Department of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University(IMSIU), P.O. Box, 90950, Riyadh, 11623, Saudi Arabia., Zaki MEA; Department of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University(IMSIU), P.O. Box, 90950, Riyadh, 11623, Saudi Arabia., Algethami FK; Department of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University(IMSIU), P.O. Box, 90950, Riyadh, 11623, Saudi Arabia., Mahmoud HK; Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt.

Publikováno v: Heliyon [Heliyon] 2024 May 10; Vol. 10 (10), pp. e31082. Date of Electronic Publication: 2024 May 10 (Print Publication: 2024).

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Anticancer behaviour of 2,2'-(pyridin-2-ylmethylene)bis(5,5-dimethylcyclohexane-1,3-dione)-based palladium(II) complex and its DNA, BSA binding propensity and DFT study.

Autor: Ragheb MA; Department of Chemistry (Biochemistry Division), Faculty of Science, Cairo University, Giza, Egypt., Soliman MH; Department of Chemistry (Biochemistry Division), Faculty of Science, Cairo University, Giza, Egypt., Abdelhamid IA; Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt. Electronic address: ismail_shafy@cu.edu.eg., Shoukry MM; Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt., Haukka M; Department of Chemistry, University of Jyväskylä, P.O. Box 35, Jyväskylä FI-40014, Finland., Ragab MS; Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt. Electronic address: msragab@cu.edu.eg.

Publikováno v: Journal of inorganic biochemistry [J Inorg Biochem] 2024 Apr; Vol. 253, pp. 112488. Date of Electronic Publication: 2024 Jan 22.

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Novel Bis(2-cyanoacrylamide) Linked to Sulphamethoxazole: Synthesis, DNA Interaction, Anticancer, ADMET, Molecular Docking, and DFT Studies.

Autor: Ragheb MA; Department of Chemistry (Biochemistry Division), Faculty of Science, Cairo University, Giza, 12613, Egypt., Mohamed FG; Department of Chemistry (Biochemistry Division), Faculty of Science, Cairo University, Giza, 12613, Egypt., Diab HM; Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt., Ragab MS; Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt., Emara M; Center for Aging and Associated Diseases, Zewail City of Science, Technology and innovation, 12578-, Giza, Egypt., Elwahy AHM; Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt., Abdelhamid IA; Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt., Soliman MH; Department of Chemistry (Biochemistry Division), Faculty of Science, Cairo University, Giza, 12613, Egypt.

Publikováno v: Chemistry & biodiversity [Chem Biodivers] 2024 Apr; Vol. 21 (4), pp. e202301341. Date of Electronic Publication: 2024 Mar 08.

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Novel cyanochalcones as potential anticancer agents: apoptosis, cell cycle arrest, DNA binding, and molecular docking studies.

Autor: Ragheb MA; Department of Chemistry (Biochemistry Division), Faculty of Science, Cairo University, Giza, Egypt., Abdelrashid HE; Department of Chemistry (Biochemistry Division), Faculty of Science, Cairo University, Giza, Egypt., Elzayat EM; Biotechnology Department, Faculty of Science, Cairo University, Giza, Egypt., Abdelhamid IA; Department of Chemistry, Faculty of Science, Cairo University, Giza, Egypt., Soliman MH; Department of Chemistry (Biochemistry Division), Faculty of Science, Cairo University, Giza, Egypt.

Publikováno v: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2024 Feb 19, pp. 1-19. Date of Electronic Publication: 2024 Feb 19.

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Mitochondrial quality control in health and in Parkinson's disease.

Autor: Eldeeb MA; McGill Parkinson Program, Neurodegenerative Diseases Group, Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada., Thomas RA; McGill Parkinson Program, Neurodegenerative Diseases Group, Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada., Ragheb MA; Chemistry Department (Biochemistry Division), Faculty of Science, Cairo University, Giza, Egypt., Fallahi A; McGill Parkinson Program, Neurodegenerative Diseases Group, Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada., Fon EA; McGill Parkinson Program, Neurodegenerative Diseases Group, Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.

Publikováno v: Physiological reviews [Physiol Rev] 2022 Oct 01; Vol. 102 (4), pp. 1721-1755. Date of Electronic Publication: 2022 Apr 25.

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Hantzsch-Like Synthesis, DNA Photocleavage, DNA/BSA Binding, and Molecular Docking Studies of Bis(sulfanediyl)bis(tetrahydro-5-deazaflavin) Analogs Linked to Naphthalene Core.

Autor: Ragheb MA; Department of Chemistry (Biochemistry Division), Faculty of Science, Cairo University, Giza, 12613, Egypt., Abdelwahab RE; Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt., Darweesh AF; Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt., Soliman MH; Department of Chemistry (Biochemistry Division), Faculty of Science, Cairo University, Giza, 12613, Egypt., Elwahy AHM; Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt., Abdelhamid IA; Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt.

Publikováno v: Chemistry & biodiversity [Chem Biodivers] 2022 Sep; Vol. 19 (9), pp. e202100958. Date of Electronic Publication: 2022 Aug 31.

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