Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Raghav Shroff"'
Autor:
Jule Goike, Ching-Lin Hsieh, Andrew P. Horton, Elizabeth C. Gardner, Ling Zhou, Foteini Bartzoka, Nianshuang Wang, Kamyab Javanmardi, Andrew Herbert, Shawn Abbassi, Xuping Xie, Hongjie Xia, Pei-Yong Shi, Rebecca Renberg, Thomas H. Segall-Shapiro, Cynthia I. Terrace, Wesley Wu, Raghav Shroff, Michelle Byrom, Andrew D. Ellington, Edward M. Marcotte, James M. Musser, Suresh V. Kuchipudi, Vivek Kapur, George Georgiou, Scott C. Weaver, John M. Dye, Daniel R. Boutz, Jason S. McLellan, Jimmy D. Gollihar
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract The ongoing evolution of SARS-CoV-2 into more easily transmissible and infectious variants has provided unprecedented insight into mutations enabling immune escape. Understanding how these mutations affect the dynamics of antibody-antigen in
Externí odkaz:
https://doaj.org/article/e176e0ac10fe413398cba9041336c98a
Autor:
Emily M. Nowicki, Raghav Shroff, Jacqueline A. Singleton, Diane E. Renaud, Debra Wallace, Julie Drury, Jolene Zirnheld, Brock Colleti, Andrew D. Ellington, Richard J. Lamont, David A. Scott, Marvin Whiteley
Publikováno v:
mBio, Vol 9, Iss 2 (2018)
ABSTRACT Over half of adults experience gingivitis, a mild yet treatable form of periodontal disease caused by the overgrowth of oral microbes. Left untreated, gingivitis can progress to a more severe and irreversible disease, most commonly chronic p
Externí odkaz:
https://doaj.org/article/cd490253441c4376b1cc114f8483fea9
Autor:
Sanchita Bhadra, Arti Pothukuchy, Raghav Shroff, Austin W Cole, Michelle Byrom, Jared W Ellefson, Jimmy D Gollihar, Andrew D Ellington
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201681 (2018)
We have found that the overproduction of enzymes in bacteria followed by their lyophilization leads to 'cellular reagents' that can be directly used to carry out numerous molecular biology reactions. We demonstrate the use of cellular reagents in a v
Externí odkaz:
https://doaj.org/article/c8cea68c2ab242859670f4198d96c323
Autor:
Inyup, Paik, Phuoc H T, Ngo, Raghav, Shroff, Daniel J, Diaz, Andre C, Maranhao, David J F, Walker, Sanchita, Bhadra, Andrew D, Ellington
Publikováno v:
Biochemistry
The DNA polymerase I from Geobacillus stearothermophilus (also known as Bst DNAP) is widely used in isothermal amplification reactions, where its strand displacement ability is prized. More robust versions of this enzyme should be enabled for diagnos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8764414f6e516fa3e1091f62c4301641
https://pubmed.ncbi.nlm.nih.gov/34762799
https://pubmed.ncbi.nlm.nih.gov/34762799
Autor:
Hongyuan Lu, Daniel J. Diaz, Natalie J. Czarnecki, Congzhi Zhu, Wantae Kim, Raghav Shroff, Daniel J. Acosta, Bradley R. Alexander, Hannah O. Cole, Yan Zhang, Nathaniel A. Lynd, Andrew D. Ellington, Hal S. Alper
Publikováno v:
Nature. 604:662-667
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2049a66f8a6e44b97b3659af01e1d4d
https://doi.org/10.1038/s41586-022-04599-z
https://doi.org/10.1038/s41586-022-04599-z
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 90:1278-1290
Prediction of side chain conformations of amino acids in proteins (also termed ‘packing’) is an important and challenging part of protein structure prediction with many interesting applications in protein design. A variety of methods for packing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff2057b422a2566701d2c4608dcd28a
https://doi.org/10.1002/prot.26311
https://doi.org/10.1002/prot.26311
Autor:
Raghav Shroff, Phuoc H. T. Ngo, Daniel J. Diaz, Sanchita Bhadra, Andrew D. Ellington, Andre C. Maranhao, Inyup Paik, David J. F. Walker
Publikováno v:
Biochemistry. 62:410-418
The DNA polymerase I from Geobacillus stearothermophilus (also known as Bst DNAP) is widely used in isothermal amplification reactions, where its strand displacement ability is prized. More robust versions of this enzyme should be enabled for diagnos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed3c1631add22c8a621d58b8a3ccdc9f
https://doi.org/10.1021/acs.biochem.1c00451
https://doi.org/10.1021/acs.biochem.1c00451
Autor:
Isaac Donnell, Raghav Shroff, Daniel J. Diaz, Barrett R. Morrow, Andrew D. Ellington, Ross Thyer, Ankur Annapareddy, Jimmy Gollihar, Austin W. Cole
Publikováno v:
ACS Synthetic Biology. 9:2927-2935
Despite the promise of deep learning accelerated protein engineering, examples of such improved proteins are scarce. Here we report that a 3D convolutional neural network trained to associate amino acids with neighboring chemical microenvironments ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::620342efdd3a1f536dfe8afc0b35414b
https://doi.org/10.1021/acssynbio.0c00345
https://doi.org/10.1021/acssynbio.0c00345
Autor:
Raghav Shroff, Jared W. Ellefson, Siyuan S. Wang, Alexander A. Boulgakov, Randall A. Hughes, Andrew D. Ellington
Publikováno v:
ACS synthetic biology. 11(2)
DNA is increasingly being explored as an alternative medium for digital information storage, but the potential information loss from degradation and associated issues with error during reading challenge its wide-scale implementation. To address this,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::156a2f4176a838c3bd4d04ff6415674d
https://pubmed.ncbi.nlm.nih.gov/35113518
https://pubmed.ncbi.nlm.nih.gov/35113518
Autor:
Natalie Czarnecki, B. Alexander, D. J. Acosta, Daniel J. Diaz, Yan Zhang, Raghav Shroff, Wantae Kim, Andrew D. Ellington, H. Cole, Hal S. Alper, Canjun Zhu, Nathaniel A. Lynd, Hongyuan Lu
Plastic waste poses an ecological challenge1. While current plastic waste management largely relies on unsustainable, energy-intensive, or even hazardous physicochemical and mechanical processes, enzymatic degradation offers a green and sustainable r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7854731356e5000879afba67c553717d
https://doi.org/10.1101/2021.10.10.463845
https://doi.org/10.1101/2021.10.10.463845
