Mitochondrial volume fraction and translation duration impact mitochondrial mRNA localization and protein synthesis

Autor: Evelina Tutucci, Fan Xu, Susanne M. Rafelski, Joonhyuk Choi, Ximena G. Arceo, Brian M. Zid, Raghav Chanchani, Robert H. Singer, Jingwen Yu, Yang S. Chen, Matheus P. Viana, Tatsuhisa Tsuboi

Publikováno v: eLife, Vol 9 (2020)
Tsuboi, T, Viana, M P, Xu, F, Yu, J, Chanchani, R, Arceo, X G, Tutucci, E, Choi, J, Chen, Y S, Singer, R H, Rafelski, S M & Zid, B M 2020, ' Mitochondrial volume fraction and translation duration impact mitochondrial mRNA localization and protein synthesis ', eLife, vol. 9, e57814, pp. 1-24 . https://doi.org/10.7554/eLife.57814, https://doi.org/10.7554/ELIFE.57814
eLife, 9:e57814, 1-24. eLife Sciences Publications
eLife

Mitochondria are dynamic organelles that must precisely control their protein composition according to cellular energy demand. Although nuclear-encoded mRNAs can be localized to the mitochondrial surface, the importance of this localization is unclea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04c6178e601ad34e330a28537b67a25d
https://doi.org/10.7554/elife.57814

Mitochondrial volume fraction controls translation of nuclear-encoded mitochondrial proteins

Autor: Robert H. Singer, Fan Xu, Joonhyuk Choi, Brian M. Zid, Raghav Chanchani, Evelina Tutucci, Ximena G. Arceo, Matheus P. Viana, Susanne M. Rafelski, Tatsuhisa Tsuboi, Jingwen Yu, Yang S. Chen

Mitochondria are dynamic in their size and morphology yet must also precisely control their protein composition according to cellular energy demand. This control is particularly complicated for mitochondria, as they must coordinate gene expression fr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47e09dae4457720f5f4b15e76162a41a