Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Raggon Jeffrey W"'
Akademický článek
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Autor:
Chinigo, Gary M., McInturff, Emma L., Bagley, Scott W., Barnhart, Richard W., Blakemore, David C., Han, Lu, Lee, Taegyo, Magano, Javier, McWilliams, J. Christopher, Monfette, Sebastien, Mousseau, James J., Pan, Senliang, Pedro, Dylan, Perfect, Hahdi H., Raggon, Jeffrey W., Rose, Peter R., Sagal, John, Trujillo, John I., Van Haitsma, Jared, Vetelino, Michael G.
Publikováno v:
Organic Process Research & Development; 6/21/2024, Vol. 28 Issue 6, p2247-2259, 13p
Akademický článek
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Autor:
Algera, Russell F., Davidson, Andrew, Herbert, David K., Lian, Yajing, Liu, Fangfang, Liu, Yiyang, Nematalla, Asaad, Piper, Jared L., Magano, Javier, Monfette, Sebastien, Nguyen, Bao, Raggon, Jeffrey W., Rainville, Joseph P., Rane, Anil, Tao, Yong, Wang, Ke, Yayla, Hatice G.
Publikováno v:
Synthesis; Feb2024, Vol. 56 Issue 4, p686-692, 7p
Akademický článek
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Autor:
Baolin Wu, Mark T. Maloney, Mark D. McLaws, Zhihui Peng, Miguel Gonzalez, Asaad S. Nematalla, John F. Sagal, Teresa W. Makowski, Jian Tao, Amelie Dion, Alan M. Happe, J. Christopher McWilliams, Cheryl Myers Hayward, Lu Jiangping, Bryan Li, Steven M. Guinness, Raggon Jeffrey W, Richard W. Barnhart, Jade D. Nelson, Gerald A. Weisenburger, Denghui Bao, Jeffrey T. Kohrt
Publikováno v:
Organic Process Research & Development. 25:1440-1453
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4edcc1e61d8c4a0ab2b4c6bb7b4c127
https://doi.org/10.1021/acs.oprd.1c00126
https://doi.org/10.1021/acs.oprd.1c00126
Autor:
Cheryl Myers Hayward, Ruggeri Sally G, David C. Limburg, John G. Van Alsten, Ruizhi Li, Steve M. Guinness, John C. Lucas, Scott Bader, Steve Hoagland, Bryan Li, Raggon Jeffrey W, J. Christopher McWilliams
Publikováno v:
Journal of Flow Chemistry. 10:145-156
Under continuous processing conditions, C-N bond formation via SN2 and SNAr substitutions by amines can be an effective preparative method, especially when volatile amines are used under high pressure and temperature. We have demonstrated SN2 substit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b47c098a0c88d457bfddad5da51835b6
https://doi.org/10.1007/s41981-019-00049-6
https://doi.org/10.1007/s41981-019-00049-6
Autor:
Neal W. Sach, Bryan Li, Jacqui Elizabeth Hoffman, Raggon Jeffrey W, Richard W. Barnhart, Asaad S. Nematalla, Paul G. Richardson, John D. Weaver
Publikováno v:
Organic Process Research & Development. 22:1289-1293
The original synthesis of lorlatinib (1) was applied and improved in the first GMP campaign. In this approach, a slow addition of the boronate ester was critical in suppressing the formation of a h...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40be8ddbf78969dbc3a076f21249dfd2
https://doi.org/10.1021/acs.oprd.8b00210
https://doi.org/10.1021/acs.oprd.8b00210
Autor:
Feng Xichun, Michael Fichtner, Miguel Gonzalez, Dan Campos, Hannah Murnen, Robert John Maguire, Shelly X. Li, Jason Mustakis, Song-yuan Zheng, Chris. R. Voss, Steven M. Guinness, Steve Hoagland, Baolin Wu, J. Christopher McWilliams, Hui Kim, Lu Jiangping, Bryan Feyock, Matthew Johnson, Evan Sohodski, Bryan Li, Sun Xingfang, Raggon Jeffrey W
Publikováno v:
Organic Process Research & Development. 22:707-720
Anhydrous tert-butyl hydroperoxide (TBHP) is a powerful oxidizing agent in many chemical transformations. Despite the versatility in organic reactions, the use of anhydrous TBHP has been greatly limited because of safety concerns over its shipping, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de8ae7ae001a6a7d95d0e2a719120519
https://doi.org/10.1021/acs.oprd.8b00083
https://doi.org/10.1021/acs.oprd.8b00083
Autor:
Thuy-Trinh Nguyen, Xiaoping Cao, Usa Reilly, Fengwei Liu, Jianmin Sun, Dave R. Bill, Karl Granskog, Yue Shen, Wilcox Glenn Ernest, Cheryl Myers Hayward, Michael Coutant, Daniel W. Widlicka, Bin Li, Magee Thomas Victor, Peter W. Rose, Thomas Andrew Brandt, Rainville Joseph Philip, Wei Liu, Richard A. Buzon, Haijian Dou, Mark Edward Flanagan, Bryan Li, Raggon Jeffrey W
Publikováno v:
Organic Process Research & Development. 16:788-797
Process development and the multikilogram synthesis of a novel azetidinyl ketolide antibiotic is described. Starting with clarithromycin, the eight-step synthesis features several telescoped operations and direct isolations, which results in a signif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecd0809c7fb8f8951638555baa51fa62
https://doi.org/10.1021/op300064b
https://doi.org/10.1021/op300064b