TFEB Overexpression, Not mTOR Inhibition, Ameliorates RagCS75Y Cardiomyopathy

Autor: Xiaolei Xu, Linghui Lu, Alexey V. Dvornikov, Xueying Lin, Xiao Ma, Maengjo Kim, Timothy M. Olson, Yonghe Ding, Ping Zhu

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 5494, p 5494 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 11

A de novo missense variant in Rag GTPase protein C (RagCS75Y) was recently identified in a syndromic dilated cardiomyopathy (DCM) patient. However, its pathogenicity and the related therapeutic strategy remain unclear. We generated a zebrafish RragcS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df655d7bd880cc01bb7cf2647f6272a1
https://www.mdpi.com/1422-0067/22/11/5494