Zobrazeno 1 - 10
of 1 100
pro vyhledávání: '"Rafik M"'
Autor:
Rania El Hosary, Mahmoud H. Teaima, Mohamed El-Nabarawi, Yousra Yousry, Mahmoud Eltahan, Ahmed Bakr, Hussein Aboelela, Rehab Abdelmonem, Rafik M. Nassif
Publikováno v:
Saudi Pharmaceutical Journal, Vol 32, Iss 1, Pp 101912- (2024)
Objective: This study aimed to extract and separate the organic coloring agent known as Curcumin from the rhizomes of Curcuma longa, and then to create Spanlastics that were loaded with curcumin using the ethanol injection technique. The optimized Sp
Externí odkaz:
https://doaj.org/article/cd06f1c47007430085535a299554af45
Autor:
Maen Abdelrahim, Abdullah Esmail, Godsfavour Umoru, Kiersten Westhart, Ala Abudayyeh, Ashish Saharia, Rafik M. Ghobrial
Publikováno v:
Current Oncology, Vol 29, Iss 6, Pp 4267-4273 (2022)
Systemic combination therapy of immune checkpoint inhibitors and vascular endothelial growth factors have provided the basis for improved outcomes in select patients with unresectable or metastatic hepatocellular carcinoma. However, for patients with
Externí odkaz:
https://doaj.org/article/22cd82424e3848c59978206e5cdc5e83
Autor:
Maen Abdelrahim, Hadeel Al-Rawi, Abdullah Esmail, Jiaqiong Xu, Godsfavour Umoru, Fahad Ibnshamsah, Ala Abudayyeh, David Victor, Ashish Saharia, Robert McMillan, Ebtesam Al Najjar, Doaa Bugazia, Maryam Al-Rawi, Rafik M. Ghobrial
Publikováno v:
Current Oncology, Vol 29, Iss 5, Pp 3585-3594 (2022)
Background: The management of cholangiocarcinoma is continually reviewed on a current evidence basis to develop practice guidelines and consensus statements. However, the standardized treatment guidelines are still unclear for cholangiocarcinoma pati
Externí odkaz:
https://doaj.org/article/6e6e02d14cb8444d9a1263a635cb1dc4
Autor:
Mou Wen, Yuanlin Ying, Xiang Xiao, Preston R. Arnold, Guangchuan Wang, Xiufeng Chu, Rafik M. Ghobrial, Xian C. Li
Publikováno v:
JCI Insight, Vol 7, Iss 23 (2022)
BRD4 is a bromodomain extraterminal domain family member and functions primarily as a chromatin reader regulating genes involved in cell-fate decisions. Here, we bred Brd4fl/fl Ox40-Cre mice in which Brd4 was conditionally deleted in OX40-expressing
Externí odkaz:
https://doaj.org/article/b49ac9ddcb264861b53b11e0e8ad3b0f
Autor:
Ahmed Uosef, Arijita Subuddhi, Annie Lu, Henry V. Ubelaker, Christof Karmonik, Jarek Wosik, Rafik M. Ghobrial, Malgorzata Kloc
Publikováno v:
Journal of Magnetic Resonance Open, Vol 12, Iss , Pp 100085- (2022)
Gadolinium-based MRI contrast agent Dotarem is commonly used in the clinic. Free Gd3+ is very toxic. Because the crystallographic radius of Gd3+ and Ca2+ is very similar, Gd3+ can compete with Ca2+ in the regulations of cellular functions. Gadolinium
Externí odkaz:
https://doaj.org/article/132a4f1e0d9e46dfaadd38988576dc94
Autor:
Maen Abdelrahim, Abdullah Esmail, Jiaqiong Xu, Godsfavour Umoru, Hadeel Al-Rawi, Ashish Saharia, Ala Abudayyeh, David Victor, Robert McMillan, Sudha Kodali, Rafik M. Ghobrial
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundCholangiocarcinoma management is constantly being updated in view of existing evidence in order to establish practice guidelines and consensus statements. However, the available treatment guidelines to optimize outcomes for cholangiocarcino
Externí odkaz:
https://doaj.org/article/ceaf7288193c4b56bffd364946f83ee9
Publikováno v:
African Journal of Urology, Vol 27, Iss 1, Pp 1-8 (2021)
Abstract Background The aim of this work is to study the role of non-contrast MRI in pre-surgical evaluation of renal masses in renal impairment patients as confirmed by both intraoperative and histopathological findings. Intraoperative and histopath
Externí odkaz:
https://doaj.org/article/86953ab3b0bd4602a489edfe7463f5f9
Autor:
Malgorzata Kloc, Ahmed Uosef, Arijita Subuddhi, Jacek Z. Kubiak, Rafal P. Piprek, Rafik M. Ghobrial
Publikováno v:
Biology, Vol 11, Iss 8, p 1121 (2022)
This review introduces the subject of senescence, aging, and the formation of senescent multinucleated giant cells. We define senescence and aging and describe how molecular and cellular senescence leads to organismal senescence. We review the latest
Externí odkaz:
https://doaj.org/article/33063bae3eae4de5b9c846ae14190341
Publikováno v:
Transplantation Reports, Vol 3, Iss 4, Pp 21-28 (2018)
Chronic rejection of transplanted organs remains an unresolved issue in clinical organ transplantation. The macrophages play a crucial role in the development of chronic rejection. We showed previously that macrophage-specific deletion of RhoA or Rho
Externí odkaz:
https://doaj.org/article/4c97714d7f1b4401bd402f27afe3268a
Autor:
Priyanka Chanana, Ahmed Uosef, Nicole Vaughn, Martha Suarez-Villagran, Rafik M. Ghobrial, Malgorzata Kloc, Jarek Wosik
Publikováno v:
Cells, Vol 11, Iss 5, p 757 (2022)
Magnetic resonance imaging (MRI) is widely used in diagnostic medicine. MRI uses the static magnetic field to polarize nuclei spins, fast-switching magnetic field gradients to generate temporal and spatial resolution, and radiofrequency (RF) electrom
Externí odkaz:
https://doaj.org/article/bd31fa091042406ab78905f8448ab32f