Engineered interleukin-6-derived cytokines recruit artificial receptor complexes and disclose CNTF signaling via the OSMR

Autor: Rafii, Puyan, Cruz, Patricia Rodrigues, Ettich, Julia, Seibel, Christiane, Padrini, Giacomo, Wittich, Christoph, Lang, Alexander, Petzsch, Patrick, Köhrer, Karl, Moll, Jens M., Floss, Doreen M., Scheller, Jürgen

Publikováno v: In Journal of Biological Chemistry May 2024 300(5)

Synthetic receptor platform to identify loss-of-function single nucleotide variants and designed mutants in the death receptor Fas/CD95

Autor: Minafra, Anna Rita, Rafii, Puyan, Mossner, Sofie, Bazgir, Farhad, Floss, Doreen M., Moll, Jens M., Scheller, Jürgen

Publikováno v: In Journal of Biological Chemistry

Exploring the landscape of synthetic IL‐6‐type cytokines.

Autor: Scheller, Jürgen, Ettich, Julia, Wittich, Christoph, Pudewell, Silke, Floss, Doreen M., Rafii, Puyan

Publikováno v: FEBS Journal; May2024, Vol. 291 Issue 10, p2030-2050, 21p

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Interleukin‐11 receptor is an alternative α‐receptor for interleukin‐6 and the chimeric cytokine IC7.

Autor: Weitz, Hendrik T.¹ (AUTHOR), Ettich, Julia¹ (AUTHOR), Rafii, Puyan¹ (AUTHOR), Wittich, Christoph¹ (AUTHOR), Schultz, Laura¹ (AUTHOR), Frank, Nils C.¹ (AUTHOR), Heise, Denise¹ (AUTHOR), Krusche, Matthias¹ (AUTHOR), Lokau, Juliane² (AUTHOR), Garbers, Christoph² (AUTHOR), Behnke, Kristina¹ (AUTHOR), Floss, Doreen M.¹ (AUTHOR), Kolmar, Harald^3,4 (AUTHOR), Moll, Jens M.¹ (AUTHOR), Scheller, Jürgen¹ (AUTHOR) jscheller@uni-duesseldorf.de

Publikováno v: FEBS Journal. Oct2024, p1. 14p. 6 Illustrations.