Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Rafia A, Baba"'
Autor:
Rafia A. Baba, Hilal A. Mir, Taseem A. Mokhdomi, Hina F. Bhat, Ajaz Ahmad, Firdous A. Khanday
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
P66Shc and Rac1 proteins are responsible for tumor-associated inflammation, particularly in brain tumors characterized by elevated oxidative stress and increased reactive oxygen species (ROS) production. Quercetin, a natural polyphenolic flavonoid, i
Externí odkaz:
https://doaj.org/article/98ef9c3e76304a92a4a0e9c96a529767
Autor:
Shahid M. Baba, Zafar A. Shah, Khushboo Javaid, Arshad A. Pandith, Javeed Rasool, Sajad A. Geelani, Rafia A. Baba, Shajrul Amin, Gul Mohammad
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Background: Methylenetetrahydrofolate reductase (MTHFR) gene is a crucial regulator of folate metabolism and its two prominent polymorphic variants C677T and A1298C lead to decreased MTHFR enzyme activity.Aim of the Study: We planned this case–cont
Externí odkaz:
https://doaj.org/article/80348a6e5e6f40b49d6ebac4a423e07a
Autor:
Tahir Mohiuddin Malla, Zafar Amin Shah, Aashiq Hussain Bhat, Manzoor Ahmad Malik, Rafia Anjum Baba, Roohi Rasool, Javaid Rasool, Sozi Ashaq, Faizanul Haq
Publikováno v:
Gene. 856
Evidence suggests that ETV6/RUNX1 translocation in pediatric acute lymphocytic leukemia shows geographical variation. Therefore, the present study aimed at unveiling the incidence of ETV6/RUNX1 fusion in pediatric acute lymphocytic leukemia cases of
Publikováno v:
Canadian Journal of Clinical Nutrition. :78-106
Autor:
Muneesa Bashir, Khurshid Iqbal Andrabi, Rafia A. Baba, Firdous A. Khanday, Sehar Saleem Bhat, Umar Mushtaq, Hina F. Bhat, Arif Ali Parray
Publikováno v:
NeuroMolecular Medicine. 16:137-149
We have previously shown the involvement of p66shc in mediating apoptosis. Here, we demonstrate the novel mechanism of β-Amyloid-induced toxicity in the mammalian cells. β-Amyloid leads to the phosphorylation of p66shc at the serine 36 residue and
Autor:
Rafia A. Baba, Hina F. Bhat, Lateef A. Wani, Muneesa Bashir, Mudasir M. Wani, Sumyra K. Qadri, Firdous A. Khanday
Publikováno v:
Disease Markers, Vol 32, Iss 4, Pp 273-279 (2012)
The expression of E3B1/ABI-1 protein and its role in cancer progression and prognosis are largely unknown in the majority of solid tumors. In this study, we examined the expression pattern of E3B1/ABI-1 protein in histologically confirmed cases of es
Autor:
Hina F. Bhat, Rafia A. Baba, Safder Saeed, Firdous A. Khanday, Deeba Kirmani, Mudassir Maqbool Wani, Muneesa Bashir, Khursheed Alam Wani, Nisar A Wani
Publikováno v:
Biomarkers. 16:31-36
We studied the expression of α1-syntrophin (SNTA1) protein in histologically confirmed esophageal, stomach, lung, colon, rectal and breast cancerous tissue samples. Our results suggest a significant decrease in the expression level of SNTA1 protein
Autor:
Sehar Saleem Bhat, Taseem A. Mokhdomi, Firdous A. Khanday, Deeba Kirmani, Arif Ali Parray, Umar Mushtaq, Hina F. Bhat, Mudassir Maqbool Wani, Sanaullah Kuchay, Rafia A. Baba, Lateef A. Wani
Publikováno v:
Cancer investigation. 32(8)
Expression analysis of MKK6 protein in solid tumors has never been investigated. Here, we report systematic analysis of MKK6 protein in different types of human tumor samples using western blotting and immunofluorescence techniques. We observed signi
Publikováno v:
British Journal of Cancer
Background: Alpha-1-syntrophin (SNTA1) has been implicated in the activation of Rac1. However, the underlying mechanism has not yet been explored. Here, we show that a novel complex, involving SNTA1, P66shc, and Grb2 proteins, is involved in Rac1 act
Autor:
Deeba Kirmani, Mohammad Afzal Zargar, Nisar A Wani, Khurshid Iqbal Andrabi, Firdous A. Khanday, Hina F. Bhat, Sameer Naqash, Rouf Hamza, Rafia A. Baba, Muneesa Bashir
Publikováno v:
Cell Communication and Signaling : CCS
Cell Communication and Signaling, Vol 8, Iss 1, p 13 (2010)
Cell Communication and Signaling, Vol 8, Iss 1, p 13 (2010)
Members of Shc (src homology and collagen homology) family, p46shc, p52shc, p66shc have known to be related to cell proliferation and carcinogenesis. Whereas p46shc and p52shc drive the reaction forward, the role of p66shc in cancers remains to be un