Výsledky vyhledávání - "Raffo-Romero A"

Akademický článek

Inhibition of furin in CAR macrophages directs them toward a proinflammatory phenotype and enhances their antitumor activities

Autor: Lydia Ziane-Chaouche, Antonella Raffo-Romero, Nawale Hajjaji, Firas Kobeissy, Donna Pinheiro, Soulaimane Aboulouard, Adeline Cozzani, Suman Mitra, Isabelle Fournier, Dasa Cizkova, Michel Salzet, Marie Duhamel

Publikováno v: Cell Death and Disease, Vol 15, Iss 12, Pp 1-16 (2024)

Abstract Chimeric antigen receptor (CAR)-T-cell therapy has revolutionized cellular immunotherapy, demonstrating remarkable efficacy in hematological cancers. However, its application in solid tumors faces significant challenges, including limited T-

Externí odkaz: https://doaj.org/article/05aeac0709be4a5ba789061c3074d13d

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Akademický článek

A co-culture system of macrophages with breast cancer tumoroids to study cell interactions and therapeutic responses

Autor: Raffo-Romero, Antonella, Ziane-Chaouche, Lydia, Salomé-Desnoulez, Sophie, Hajjaji, Nawale, Fournier, Isabelle, Salzet, Michel, Duhamel, Marie

Publikováno v: In Cell Reports Methods 17 June 2024 4(6)

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Akademický článek

Heimdall, an alternative protein issued from a ncRNA related to kappa light chain variable region of immunoglobulins from astrocytes: a new player in neural proteome

Autor: Alice Capuz, Sylvain Osien, Tristan Cardon, Mélodie Anne Karnoub, Soulaimane Aboulouard, Antonella Raffo-Romero, Marie Duhamel, Dasa Cizkova, Marco Trerotola, David Devos, Firas Kobeissy, Fabien Vanden Abeele, Amélie Bonnefond, Isabelle Fournier, Franck Rodet, Michel Salzet

Publikováno v: Cell Death and Disease, Vol 14, Iss 8, Pp 1-23 (2023)

Abstract The dogma “One gene, one protein” is clearly obsolete since cells use alternative splicing and generate multiple transcripts which are translated into protein isoforms, but also use alternative translation initiation sites (TISs) and ter

Externí odkaz: https://doaj.org/article/c1f0c4f332644e5aa7a4c789a3d99d88

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Akademický článek

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Akademický článek

Astrocytes express aberrant immunoglobulins as putative gatekeeper of astrocytes to neuronal progenitor conversion

Publikováno v: Cell Death and Disease, Vol 14, Iss 4, Pp 1-16 (2023)

Abstract Using multi-omics analyses including RNAseq, RT-PCR, RACE-PCR, and shotgun proteomic with enrichment strategies, we demonstrated that newborn rat astrocytes produce neural immunoglobulin constant and variable heavy chains as well as light ch

Externí odkaz: https://doaj.org/article/4a879d4e7d604bcc8c22d0f2991b82bb

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Akademický článek

Establishment and characterization of canine mammary tumoroids for translational research

Autor: Antonella Raffo-Romero, Soulaimane Aboulouard, Emmanuel Bouchaert, Agata Rybicka, Dominique Tierny, Nawale Hajjaji, Isabelle Fournier, Michel Salzet, Marie Duhamel

Publikováno v: BMC Biology, Vol 21, Iss 1, Pp 1-19 (2023)

Abstract Background Cancer heterogeneity is a main obstacle for the development of effective therapies, as its replication in in vitro preclinical models is challenging. Around 96% of developed drugs are estimated to fail from discovery to the clinic

Externí odkaz: https://doaj.org/article/ed36d527f98a4f21a823d059c58969d4

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