Sodium oxybate for the maintenance of abstinence in alcohol-dependent patients: An international, multicenter, randomized, double-blind, placebo-controlled trial.

Autor: Guiraud J; Department of Psychiatry, Amsterdam Neuroscience, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; D&A Pharma, Paris, France., Addolorato G; Alcohol Use Disorder and Alcohol Related Disease Unit, Department of Internal Medicine and Gastroenterology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.; Internal Medicine Unit, Columbus-Gemelli Hospital, Department of Internal Medicine and Gastroenterology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy., Antonelli M; Internal Medicine Unit, Columbus-Gemelli Hospital, Department of Internal Medicine and Gastroenterology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy., Aubin HJ; French Institute of Health and Medical Research (Inserm), Centre de Recherche en Epidémiologie et Santé des Populations (CESP), Universite Paris-Saclay, Villejuif, France.; Addiction Research and Treatment Center, Paul Brousse Hospital, Paris-Sud University, Villejuif, France., de Bejczy A; Section of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Goteborg, Sweden., Benyamina A; Addiction Research and Treatment Center, Paul Brousse Hospital, Paris-Sud University, Villejuif, France., Cacciaglia R; Laboratorio Farmaceutico CT, San Remo, Italy., Caputo F; Department of Internal Medicine, SS. Annunziata Hospital, Cento (Ferrara), University of Ferrara, Italy.; Centre for the Study and Treatment of Alcohol-Related Diseases, Department of Translational Medicine, University of Ferrara, Ferrara, Italy., Dematteis M; Department of Addiction Medicine, Grenoble-Alpes University Hospital, and Faculty of Medicine, Grenoble Alpes University, France., Ferrulli A; Department of Endocrinology, Nutrition and Metabolic Diseases, IRCCS MultiMedica, Milan, Italy.; Department of Biomedical Sciences for Health, University of Milan, Milan, Italy., Goudriaan AE; Department of Psychiatry, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.; Arkin, Department of Research and Quality of Care, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands., Gual A; Psychiatry Department, Neurosciences Institute, Hospital Clinic, IDIBAPS, Barcelona, Spain., Lesch OM; University Clinic of Psychiatry and Psychotherapy, Department of Social Psychiatry, Medical University of Vienna, Austria., Maremmani I; Santa Chiara University Hospital, University of Pisa, Italy., Mirijello A; Department of Medical Sciences, IRCCS Casa Sollievo della Sofferenza General Hospital, San Giovanni Rotondo (FG), Italy., Nutt DJ; Centre for Neuropsychopharmacology, Imperial College London, United Kingdom., Paille F; Department of Addiction Treatment, University Hospital, Vandoeuvre-lès-Nancy, France., Perney P; Addiction Medicine, CHU Nîmes, France., Poulnais R; D&A Pharma, Paris, France., Raffaillac Q; D&A Pharma, Paris, France., Rehm J; Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.; Department of Psychiatry, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.; Clinical Psychology & Psychotherapy Technical University Dresden, Dresden, Germany.; Department of International Health Projects, Institute for Leadership and Health Management, I.M. Sechenov First Moscow State Medical University, Moscow, Russia., Rolland B; SUAL, HCL, CH Le Vinatier; Univ Lyon; UCBL; INSERM U1028; CNRS UMR5292, Centre de Recherche en Neuroscience de Lyon (CRNL), Bron, France., Rotondo C; Centro di Riferimento Alcologico della Regione Lazio (CRARL), Dipartimento di Salute Mentale, Roma, Italy., Scherrer B; Bruno Scherrer Conseil, Saint Arnoult en Yvelines, France., Simon N; Aix Marseille Univ, APHM, INSERM, IRD, SESSTIM, Hop Sainte Marguerite, Department of Clinical Pharmacology, CAP-TV, Marseille, France., Skala K; Department of Child and Adolescent Psychiatry, Medical University of Vienna, Austria., Söderpalm B; Laboratorio Farmaceutico CT, San Remo, Italy., Somaini L; Addiction Treatment Center, Local Health Unit, ASL Biella, Italy., Sommer WH; Medical Faculty, Institute of Psychopharmacology, Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany.; Institute of Psychopharmacology, Central Institute of Mental Health, Heidelberg University, Mannheim, Germany., Spanagel R; Institute of Psychopharmacology, Central Institute of Mental Health, Heidelberg University, Mannheim, Germany., Vassallo GA; Department of Internal Medicine, Barone Lombardo Hospital, Canicattì, Italy., Walter H; Santa Chiara University Hospital, University of Pisa, Italy., van den Brink W; Department of Psychiatry, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.

Publikováno v: Journal of psychopharmacology (Oxford, England) [J Psychopharmacol] 2022 Oct; Vol. 36 (10), pp. 1136-1145. Date of Electronic Publication: 2022 Jul 07.

Baseline severity and the prediction of placebo response in clinical trials for alcohol dependence: A meta-regression analysis to develop an enrichment strategy.

Autor: Scherrer B; Bruno Scherrer Conseil, Saint Arnoult en Yvelines, France., Guiraud J; Department of Psychiatry, Amsterdam Neuroscience, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; DA Pharma, Paris, France., Addolorato G; Alcohol Use Disorder and Alcohol Related Disease Unit, Department of Internal Medicine and Gastroenterology, Fondazione Policlinico Universitario A.Gemelli IRCCS, Rome, Italy.; Internal Medicine Unit, Department of Internal Medicine and Gastroenterology, Columbus-Gemelli Hospital, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy., Aubin HJ; Centre de Recherche en Epidémiologie et Santé des Populations (CESP), French Institute of Health and Medical Research (Inserm), Paris, France.; Addiction Research and Treatment Center, Paul Brousse Hospital, Paris-Sud University, Villejuif, France., de Bejczy A; Section of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Benyamina A; Addiction Research and Treatment Center, Paul Brousse Hospital, Paris-Sud University, Villejuif, France., van den Brink W; Department of Psychiatry, Amsterdam Neuroscience, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Caputo F; Department of Translational Medicine, University of Ferrara, Ferrara, Italy.; Department of Translational Medicine, Center for the Study and Treatment of Alcohol-Related Diseases, University of Ferrara, Ferrara, Italy.; Department of Translational Medicine, Center for the Study and Treatment of Chronic Inflammatory Bowel Diseases (IBD) and Gastroenterological Manifestations of Rare Diseases, University of Ferrara, Ferrara, Italy.; Department of Internal Medicine, Santissima Annunziata Hospital, Cento (Ferrara), University of Ferrara, Ferrara, Italy., Dematteis M; Department of Addiction Medicine, Faculty of Medicine, Grenoble Alpes University Hospital, Grenoble Alpes University, Grenoble, France., Goudriaan AE; Department of Psychiatry, Amsterdam Neuroscience, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.; Department of Research and Quality of Care, Arkin, Amsterdam, The Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands., Gual A; Psychiatry Department, Neurosciences Institute, Hospital Clinic, IDIBAPS, Barcelona, Spain., Kiefer F; Medical Faculty Mannheim, Central Institute of Mental Health, Institute of Psychopharmacology, University of Heidelberg, Heidelberg, Germany.; Bethania Hospital for Psychiatry, Psychosomatics, and Psychotherapy, Greifswald, Germany., Leggio L; Clinical Psychoneuroendocrinology and Neuropsychopharmacology Section, Translational Addiction Medicine Branch, National Institute on Drug Abuse Intramural Research Program and National Institute on Alcohol Abuse and Alcoholism Division of Intramural Clinical and Basic Research, National Institutes of Health, Baltimore and Bethesda, Maryland, USA.; Medication Development Program, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, Maryland, USA.; Department of Behavioral and Social Sciences, Center for Alcohol and Addiction Studies, Brown University, Providence, Rhode Island, USA.; Division of Addiction Medicine, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.; Department of Neuroscience, Georgetown Medical Center, Washington, District of Columbia, USA., Lesch OM; Department of Social Psychiatry, University for Psychiatry and Psychotherapy, Vienna, Austria., Maremmani I; Santa Chiara University Hospital, University of Pisa, Pisa, Italy., Nutt DJ; Centre for Neuropsychopharmacology, Imperial College London, London, UK., Paille F; Department of Addiction Treatment, University Hospital, Vandoeuvre-lès-Nancy, France., Perney P; Addiction Medicine, Hospital Grau-du-Roi, Nimes, France., Poulnais R; DA Pharma, Paris, France., Raffaillac Q; DA Pharma, Paris, France., Rehm J; Centre for Addiction and Mental Health, Institute for Mental Health Policy Research, Toronto, Ontario, Canada.; Department of Psychiatry, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.; Clinical Psychology and Psychotherapy, Technical University Dresden, Dresden, Germany.; Department of International Health Projects, Institute for Leadership and Health Management, I.M. Sechenov First Moscow State Medical University, Moscow, Russia., Rolland B; UCBL, INSERM U1028, CNRS UMR5292, Centre de Recherche en Neuroscience de Lyon (CRNL), Univ Lyon, Bron, France., Simon N; Department of Clinical Pharmacology, CAP-TV, Aix Marseille Univ, APHM, INSERM, IRD, SESSTIM, Hop Sainte Marguerite, Marseille, France., Söderpalm B; Section of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Sommer WH; Medical Faculty Mannheim, Central Institute of Mental Health, Institute of Psychopharmacology, University of Heidelberg, Heidelberg, Germany.; Central Institute of Mental Health, Institute of Psychopharmacology, Heidelberg University, Mannheim, Germany., Walter H; Department of Social Psychiatry, University for Psychiatry and Psychotherapy, Vienna, Austria., Spanagel R; Central Institute of Mental Health, Institute of Psychopharmacology, Heidelberg University, Mannheim, Germany.

Publikováno v: Alcoholism, clinical and experimental research [Alcohol Clin Exp Res] 2021 Sep; Vol. 45 (9), pp. 1722-1734. Date of Electronic Publication: 2021 Aug 21.

Helpful or Harmful? The Therapeutic Potential of Medications with Varying Degrees of Abuse Liability in the Treatment of Substance Use Disorders.

Autor: Martins, Bradford, Rutland, Will, De Aquino, Joao P., Kazer, Benjamin L., Funaro, Melissa, Potenza, Marc N., Angarita, Gustavo A.

Publikováno v: Current Addiction Reports; Dec2022, Vol. 9 Issue 4, p647-659, 13p

Advances in Alcohol Use Disorder Treatment

Advances in Alcohol Use Disorder Treatment, Volume 178 in the International Review in Neurobiology series, presents a comprehensive exploration of emerging therapies and approaches in the field. Topics in this new release include Introduction: Curren