Phagocytosis and Epithelial Cell Invasion by Crohn’s Disease-Associated Adherent-Invasive Escherichia coli Are Inhibited by the Anti-inflammatory Drug 6-Mercaptopurine

Autor: Federica Migliore, Raffaella Macchi, Paolo Landini, Moira Paroni

Publikováno v: Frontiers in Microbiology, Vol 9 (2018)

Adherent-invasive Escherichia coli (AIEC) strains are overrepresented in the dysbiotic microbiota of Crohn’s disease (CD) patients, and contribute to the onset of the chronic inflammation typical of the disease. However, the effects of anti-inflamm

Externí odkaz: https://doaj.org/article/9ee563f48c334a74be9ff064169edeb1

From Food Waste to Innovative Biomaterial: Sea Urchin-Derived Collagen for Applications in Skin Regenerative Medicine

Autor: C. Ferrario, Albana Pulaj, M. Daniela Candia Carnevali, Raffaella Macchi, Tiziana Martinello, Chiara Gomiero, Paolo Landini, Michela Sugni, Graziano Colombo, Francesco Bonasoro, Marco Vincenzo Patruno, Moira Paroni, Luca Melotti, Francesco Rusconi

Publikováno v: Marine Drugs
Marine Drugs, Vol 18, Iss 414, p 414 (2020)
Volume 18
Issue 8

Collagen-based skin-like scaffolds (CBSS) are promising alternatives to skin grafts to repair wounds and injuries. In this work, we propose that the common marine invertebrate sea urchin represents a promising and eco-friendly source of native collag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1ae3a59e5c1ddb52f8eb892fa62b44e
http://europepmc.org/articles/PMC7460064

Crystal structure of YeaZ from Pseudomonas aeruginosa

Autor: Mario Milani, Davide Vecchietti, Giovanni Bertoni, Ruggero Rusmini, Silvia Ferrara, Raffaella Macchi

Publikováno v: Biochemical and biophysical research communications
470 (2016): 460–465. doi:10.1016/j.bbrc.2016.01.008
info:cnr-pdr/source/autori:Vecchietti D, Ferrara S, Rusmini R, Macchi R, Milani M, Bertoni G/titolo:Crystal structure of YeaZ from Pseudomonas aeruginosa/doi:10.1016%2Fj.bbrc.2016.01.008/rivista:Biochemical and biophysical research communications (Print)/anno:2016/pagina_da:460/pagina_a:465/intervallo_pagine:460–465/volume:470

The Pseudomonas aeruginosa PA3685 locus encodes a conserved protein that shares 49% sequence identity with Escherichia coli YeaZ, which was recently reported as involved in the biosynthesis of threonylcarbamoyl adenosine (t(6)A), a universal modified

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c393000b97ec0073643c667b97934007
https://doi.org/10.1016/j.bbrc.2016.01.008

The small RNA ReaL: a novel regulatory element embedded in the Pseudomonas aeruginosa quorum sensing networks

Autor: Sara, Carloni, Raffaella, Macchi, Sara, Sattin, Silvia, Ferrara, Giovanni, Bertoni

Publikováno v: Environmental microbiology. 19(10)

The small RNA ReaL of the opportunistic pathogen Pseudomonas aeruginosa has been characterized. Our results indicate that ReaL contributes to P. aeruginosa virulence. In the Galleria mellonella infection model, reaL gene deletion resulted in decrease

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6b0b1115c7e6322c8b1f2e12d4713666
https://pubmed.ncbi.nlm.nih.gov/28799693

Characterization of the last step of the aerobic phenylacetic acid degradation pathway

Autor: Juan Nogales, José Luis García, Eduardo Díaz, Dagania Barzaghi, Cristina Fernández, Giovanni Bertoni, Raffaella Macchi, Federico Franchi

Publikováno v: Microbiology. 153:357-365

Phenylacetic acid (PA) degradation in bacteria involves an aerobic hybrid pathway encoded by the paa gene cluster. It is shown here that succinyl-CoA is one of the final products of this pathway in Pseudomonas putida and Escherichia coli. Moreover, i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5908295ac5cbff136c722fb155598d3e
https://doi.org/10.1099/mic.0.2006/002444-0