Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Raffaella De Paolo"'
Autor:
Raffaella De Paolo, Samanta Sarti, Sara Bernardi, Francesco Cucco, Andrea Tavosanis, Letizia Pitto, Laura Poliseno
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-5 (2023)
Abstract BRAFV600E comes as two main splicing variants. The well-studied ref isoform and the recently discovered X1 isoform are co-expressed in cancer cells and differ in terms of 3’UTR length and sequence, as well as C-term protein sequence. Here,
Externí odkaz:
https://doaj.org/article/daac89a5bbd643da9e7559100aa226dd
Autor:
Andrea Marranci, Antonella Prantera, Simona Masotti, Raffaella De Paolo, Caterina Baldanzi, Maurizio S. Podda, Serena Mero, Marianna Vitiello, Cinzia Franchin, Mariavittoria Laezza, Laura Comelli, Giorgio Arrigoni, Tiziana Cervelli, Giovanna Del Pozzo, Laura Poliseno
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-7 (2023)
Abstract In human cells BRAF oncogene is invariably expressed as a mix of two coding transcripts: BRAF-ref and BRAF-X1. These two mRNA isoforms, remarkably different in the sequence and length of their 3′UTRs, are potentially involved in distinct p
Externí odkaz:
https://doaj.org/article/0521849920fd4c4590c3cca047953758
Autor:
Samanta Sarti, Raffaella De Paolo, Chiara Ippolito, Angela Pucci, Letizia Pitto, Laura Poliseno
Publikováno v:
Biology Open, Vol 9, Iss 11 (2020)
Here, we present miniCoopR-I, an inducible upgrade of the constitutive miniCoopR vector. We developed miniCoopR-I-sponge-204 and miniCoopR-I-pre-miR-204 vectors and we successfully tested them for their ability to achieve time- (embryo/juvenile/adult
Externí odkaz:
https://doaj.org/article/d02bdc6d4afd43768f3c049f1dfbcdf9
Autor:
Silvia Pietrobono, Raffaella De Paolo, Domenico Mangiameli, Andrea Marranci, Ilaria Battisti, Cinzia Franchin, Giorgio Arrigoni, Davide Melisi, Laura Poliseno, Barbara Stecca
Publikováno v:
The Journal of biological chemistry. 298(9)
Despite recent advances in the development of BRAF kinase inhibitors (BRAFi) for BRAF-mutant melanomas, development of resistance remains a major clinical problem. In addition to genetic alterations associated with intrinsic resistance, several adapt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea4923c57a36cacbfaff14b1dac6b300
https://pubmed.ncbi.nlm.nih.gov/35944584
https://pubmed.ncbi.nlm.nih.gov/35944584
Autor:
Chiara Ippolito, Laura Poliseno, Angela Pucci, Letizia Pitto, Samanta Sarti, Raffaella De Paolo
Publikováno v:
Biology Open
article-version (VoR) Version of Record
Biology Open, Vol 9, Iss 11 (2020)
article-version (VoR) Version of Record
Biology Open, Vol 9, Iss 11 (2020)
Here, we present miniCoopR-I, an inducible upgrade of the constitutive miniCoopR vector. We developed miniCoopR-I-sponge-204 and miniCoopR-I-pre-miR-204 vectors and we successfully tested them for their ability to achieve time- (embryo/juvenile/adult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd15be55a78cb0cf87abd9e4205ed6d
http://europepmc.org/articles/PMC7657466
http://europepmc.org/articles/PMC7657466
Autor:
Marcella Fiengo, Rita Marino, Takashi Kondo, Sylvie Maiella, Antonio Emidio Fortunato, Fernanda Langellotto, Raffaella De Paolo, Stephen W. Wilson, Giulia Fasano, Filomena Ristoratore, Lorella M.T. Canzoniero, Valeria Nittoli, Alessandra Gentile, Paolo Sordino, Ugo Coppola, Francesco Aniello, Aldo Donizetti, Denis Duboule, Immacolata Porreca
Publikováno v:
Gene: X, Vol 2, Iss, Pp-(2019)
Gene X
Gene X
The paired-type homeodomain transcription factor Uncx is involved in multiple processes of embryogenesis in vertebrates. Reasoning that zebrafish genes uncx4.1 and uncx are orthologs of mouse Uncx, we studied their genomic environment and development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eb6fca69c1e7c12dac8cc68fb4c4334
https://doi.org/10.1016/j.gene.2019.100011
https://doi.org/10.1016/j.gene.2019.100011