Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Raffaele, Malinverni"'
Autor:
Frédégonde About, Stéphanie Bibert, Emmanuelle Jouanguy, Bertrand Nalpas, Lazaro Lorenzo, Vimel Rattina, Mohammed Zarhrate, Sylvain Hanein, Mona Munteanu, Beat Müllhaupt, David Semela, Nasser Semmo, Jean-Laurent Casanova, Ioannis Theodorou, Philippe Sultanik, Thierry Poynard, Stanislas Pol, Pierre-Yves Bochud, Aurélie Cobat, Laurent Abel, The Swiss Hepatitis C Cohort Study Group, The French ANRS HC EP 26 Genoscan Study Group, Francesco Negro, Antoine Hadengue, Laurent Kaiser, Laura Rubbia-Brandt, Darius Moradpour, Cristina Cellerai, Martin Rickenbach, Andreas Cerny, Gladys Martinetti, Jean-François Dufour, Meri Gorgievski, Virginie Masserey Spicher, Markus Heim, Hans Hirsch, Beat Helbling, Stephan Regenass, Raffaele Malinverni, Guenter Dollenmaier, Gieri Cathomas
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Despite the astonishing progress in treating chronic hepatitis C virus (HCV) infection with direct-acting antiviral agents, liver fibrosis remains a major health concern in HCV infected patients, in particular due to the treatment cost and insufficie
Externí odkaz:
https://doaj.org/article/6902600e7fc6453da39b73b597e71e52
Autor:
Isabelle Morard, Sophie Clément, Alexandra Calmy, Alessandra Mangia, Andrea Cerny, Andrea De Gottardi, Meri Gorgievski, Markus Heim, Raffaele Malinverni, Darius Moradpour, Beat Müllhaupt, David Semela, Stéphanie Pascarella, Pierre-Yves Bochud, Franco Negro, Swiss Hepatitis C Cohort Study Group
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106424 (2014)
BACKGROUND:The CCR5 receptor, expressed on Th1 cells, may influence clinical outcomes of HCV infection. We explored a possible link between a CCR5 32-base deletion (CCR5delta32), resulting in the expression of a non-functioning receptor, and clinical
Externí odkaz:
https://doaj.org/article/eae7ad7ec51d41b483460d277f819dc6
Autor:
Christian M Lange, Daiki Miki, Hidenori Ochi, Hans-Dieter Nischalke, Jörg Bojunga, Stéphanie Bibert, Kenichi Morikawa, Jérôme Gouttenoire, Andreas Cerny, Jean-François Dufour, Meri Gorgievski-Hrisoho, Markus H Heim, Raffaele Malinverni, Beat Müllhaupt, Francesco Negro, David Semela, Zoltan Kutalik, Tobias Müller, Ulrich Spengler, Thomas Berg, Kazuaki Chayama, Darius Moradpour, Pierre-Yves Bochud, Hiroshima Liver Study Group, Swiss Hepatitis C Cohort Study Group
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64053 (2013)
Vitamin D insufficiency has been associated with the occurrence of various types of cancer, but causal relationships remain elusive. We therefore aimed to determine the relationship between genetic determinants of vitamin D serum levels and the risk
Externí odkaz:
https://doaj.org/article/e963bbb7a51b4bcb81c9113e0b0e6429
Autor:
Lorenz Kuske, Armand Mensen, Beat Müllhaupt, Francesco Negro, David Semela, Darius Moradpour, Pierre Jean Malé, Markus H Heim, Raffaele Malinverni, Andreas Cerny, Jean-Francois Dufour
Publikováno v:
Swiss Medical Weekly, Vol 142, Iss 3132 (2012)
BACKGROUND AND AIM: Hepatocellular carcinoma (HCC) is the most frequent form of primary liver cancer and chronic infection with hepatitis C virus is one of the main risk factors for HCC. This study analyses the characteristics of the patients with ch
Externí odkaz:
https://doaj.org/article/0c90c0d537934fba9b052d581aa6c2d9
Autor:
Christian M Lange, Stephanie Bibert, Zoltan Kutalik, Philippe Burgisser, Andreas Cerny, Jean-Francois Dufour, Andreas Geier, Tilman J Gerlach, Markus H Heim, Raffaele Malinverni, Francesco Negro, Stephan Regenass, Klaus Badenhoop, Jörg Bojunga, Christoph Sarrazin, Stefan Zeuzem, Tobias Müller, Thomas Berg, Pierre-Yves Bochud, Darius Moradpour, Swiss Hepatitis C Cohort Study Group
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40159 (2012)
BACKGROUND:To perform a comprehensive study on the relationship between vitamin D metabolism and the response to interferon-α-based therapy of chronic hepatitis C. METHODOLOGY/PRINCIPAL FINDINGS:Associations between a functionally relevant polymorph
Externí odkaz:
https://doaj.org/article/6c54a69ff3b44210aa78d7d2749f4188
Autor:
Ulrich Spengler, Alexander N.R. Weber, Christoph Sarrazin, Stephan H. Bohm, Raffaele Malinverni, Lisa Wang, Jens Rasenack, Thomas Berg, Clair M. Gardiner, V Knop, Souhayla El Maadidi, Sabine Dickhöfer, Cliona O'Farrelly, Peter Buggisch, Tim Waterboer, Hartwig Klinker, Manfred Wiese, Bernd Möller, Michael Pawlita, D Deichsel, Elsbeth Probst-Müller, Pierre-Yves Bochud, Holger Hinrichsen, Janett Fischer, Manu Sharma
Publikováno v:
Gut. 66:1829-1837
Objective As pathogen sensors, Toll-like receptors (TLR) play a role in the first defence line during HCV infection. However, the impact of the DNA sensor TLR9 on the natural course of HCV infection is unknown. To address this, TLR9 promoter polymorp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::247ca03ad0acffe9b24b13cab6df1444
https://doi.org/10.1136/gutjnl-2015-310239
https://doi.org/10.1136/gutjnl-2015-310239
Autor:
Rosa Zampino, David Semela, Laura Rubbia-Brandt, Le Adinolfi, Nicola Coppola, Darius Moradpour, Beat Müllhaupt, Sophie Clément, Giovanni Cenderello, Francesco Negro, Heiner Wedemeyer, Nasser Semmo, Nicolas Goossens, Raffaele Malinverni, Markus H. Heim, Maria Stanzione, Gaia Trincucci, C. De Vito, Roberta D'Ambrosio, Alessandra Mangia, Francisco Barrera
Publikováno v:
Journal of Viral Hepatitis (2018)
It remains unclear whether hepatitis B virus (HBV) infection may modify the severity of viral steatosis in patients coinfected with chronic hepatitis C virus (HCV). We examined the influence of coinfection with HBV on prevalence of steatosis in chron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::409fe8f01249eb3e5c670ccc5ceea049
https://www.ncbi.nlm.nih.gov/pubmed/29532619
https://www.ncbi.nlm.nih.gov/pubmed/29532619
Autor:
F. Negro, Darius Moradpour, Stanislas Pol, Beat Müllhaupt, David R. Booth, Pierre-Yves Bochud, David Semela, Philippe Halfon, Thierry Poynard, Jacob George, Vijayaprakash Suppiah, Andrew H. Talal, Sina Rüeger, Laurent Argiro, M. Bourlière, Ira M. Jacobson, Bertrand Nalpas, Jean-François Dufour, Raffaele Malinverni, Markus H. Heim, A. Cerny, Etienne Patin, Laurent Abel, Zoltán Kutalik
Publikováno v:
Gut
ObjectiveThe natural course of chronic hepatitis C varies widely. To improve the profiling of patients at risk of developing advanced liver disease, we assessed the relative contribution of factors for liver fibrosis progression in hepatitis C. Desig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53b0aa29a3908db4d400f35991bd4a2
Autor:
Stéphanie Bibert, Andreas Cerny, Meri Gorgievski, Thomas Berg, Jean Villard, Emeline Gauthiez, David Semela, Jacob George, Nasser Semmo, Beat Müllhaupt, Vincent Aubert, Sina Rüeger, Zoltán Kutalik, Francesco Negro, Darius Moradpour, Ines Habfast-Robertson, Raffaele Malinverni, Markus H. Heim, Pierre-Yves Bochud
Publikováno v:
Liver International, Vol. 37, No 10 (2017) pp. 1431-1445
While hepatitis C exemplifies the role of host genetics in infectious diseases outcomes, there is no comprehensive overview of polymorphisms influencing spontaneous and/or treatment-induced hepatitis C virus clearance. We performed a systematic revie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73e7938032930fbd461e2c3ed0c1effa
https://archive-ouverte.unige.ch/unige:93774
https://archive-ouverte.unige.ch/unige:93774
Autor:
Bertrand Nalpas, Stanislas Pol, Tillman Gerlach, Thierry Poynard, Hans H. Hirsch, Raffaele Malinverni, Stephan Regenass, Stéphanie Bibert, Markus H. Heim, Nicolas Goossens, Guenter Dollenmaier, Pierre-Yves Bochud, Etienne Patin, Gladys Martinetti, Laurent Abel, L. Kuske, Beat Müllhaupt, Andreas Cerny, Meri Gorgiewski, Darius Moradpour, Julien Guergnon, Ioannis Theodorou, Marc Bourlière, Jean-François Dufour, Zoltán Kutalik, Francesco Negro
Publikováno v:
Hepatology (Baltimore Md.)
Hepatology, Vol. 55, No 2 (2012) pp. 384-94
Hepatology, Vol. 55, No 2 (2012) pp. 384-94
Genetic polymorphisms near IL28B are associated with spontaneous and treatment-induced clearance of hepatitis C virus (HCV), two processes that require the appropriate activation of the host immune responses. Intrahepatic inflammation is believed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffd42d433bb422b1f7fc8030fa85228e