Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Raffaele, Frazzi"'
Autor:
Raffaele Frazzi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
The epigenetic layer of regulation has become increasingly relevant in the research focused on tumor suppressors. KLF4 is a well-described zinc-finger transcription factor, mainly known for its role in the acquisition of cell pluripotency. Here we re
Externí odkaz:
https://doaj.org/article/e5481fc512b44b6383c01c8234ae265b
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Most of our transcribed RNAs are represented by non-coding sequences. Long non-coding RNAs (lncRNAs) are transcripts with no or very limited protein coding ability and a length >200nt. They can be epigenetically modified. N6-methyladenosine (m6A), N1
Externí odkaz:
https://doaj.org/article/f2b46296da6d4308be844e79cd71e6be
Autor:
Raffaele Frazzi
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Background The evasion from apoptosis is a common strategy adopted by most tumors, and inhibitors of apoptosis proteins (IAPs) are among the most studied molecular and therapeutic targets. BIRC3 (cellular IAP2) and BIRC5 (survivin) are two o
Externí odkaz:
https://doaj.org/article/7a68d2c7f6cb44dfbedf2c3e4dbdbc23
Publikováno v:
BioTechniques, Vol 64, Iss 2, Pp 45-51 (2018)
FTA® technologies provide the most reliable method for DNA extraction. Although FTA technologies have been widely used for genetic analysis, there is no literature on their use for epigenetic analysis yet. We present for the first time, a simple met
Externí odkaz:
https://doaj.org/article/97355d8a672d4552ab195f0016ae6cc3
Autor:
Raffaele Frazzi
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Mammalian silent information regulator 1 (SIRT1) is reported to play a role in cancers of the secretory organs, including thyroid, pancreatic endocrine, and ovarian tumors [1, 2, 3, 4]. A recent meta-analysis conducted on 37 selected studies of human
Externí odkaz:
https://doaj.org/article/2364328fe7564ddd99b008a673de5530
Publikováno v:
Biochimica et biophysica acta. Reviews on cancer. 1877(6)
SPART is a gene coding for a multifunctional protein called spartin, localized in various organelles of human cells. Mutations in the coding region are responsible for a hereditary form of spastic paraplegia called Troyer syndrome while the epigeneti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b9e71e1a21de6ac0c39feed8266a31
https://pubmed.ncbi.nlm.nih.gov/36195276
https://pubmed.ncbi.nlm.nih.gov/36195276
Autor:
Francesco Bertoni, Francesco Merli, Mariaelena Pistoni, Laura Canovi, Vincenza Ylenia Cusenza, Luciano Cascione, Raffaele Frazzi
Publikováno v:
Oncology Reports
Promoter methylation represents one of the major epigenetic mechanisms responsible for the regulation of gene expression. Hypomethylating drugs are currently approved for the treatment of myelodysplastic syndromes and acute myeloid leukemia, and some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a6e7a33c6ea30553c8d466c2c032759
https://doi.org/10.3892/or.2021.8221
https://doi.org/10.3892/or.2021.8221
Autor:
Maria Paola Bonasoni, Federica Alessandrini, Raffaele Frazzi, F P Busardò, Adriano Tagliabracci, Eva Montanari, Federico Mocchegiani, Raffaele Giorgetti
Publikováno v:
Forensic Toxicology. 37:507-516
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c84f6467f120f6f4fe66c1db30b530af
https://doi.org/10.1007/s11419-019-00478-x
https://doi.org/10.1007/s11419-019-00478-x
Autor:
Raffaele Frazzi, Manuela Guardi
Publikováno v:
Molecules, Vol 22, Iss 6, p 885 (2017)
Resveratrol (RSV) is a well known chemopreventive molecule featuring anti-cancer properties. Our paper describes the main molecular targets of RSV linked to its antiproliferative activity on lymphoma and leukemia experimental models. It discusses fur
Externí odkaz:
https://doaj.org/article/37951de7d86145a0b9d269127a01d727
Autor:
Vincenza Ylenia Cusenza, Alessandra Bisagni, Monia Rinaldini, Raffaele Frazzi, Chiara Cattani
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 4732, p 4732 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 4732, p 4732 (2021)
The cytogenetic and molecular assessment of deletions, amplifications and rearrangements are key aspects in the diagnosis and therapy of cancer. Not only the initial evaluation and classification of the disease, but also the follow-up of the tumor re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e582ffd90c64ffc0f650c1cb0f969d
https://pubmed.ncbi.nlm.nih.gov/33946969
https://pubmed.ncbi.nlm.nih.gov/33946969