Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Raffael Júnio Araújo de Castro"'
Autor:
Raffael Júnio Araújo de Castro, Clara Luna Marina, Aude Sturny-Leclère, Christian Hoffmann, Pedro Henrique Bürgel, Sarah Sze Wah Wong, Vishukumar Aimanianda, Hugo Varet, Ruchi Agrawal, Anamélia Lorenzetti Bocca, Alexandre Alanio
Publikováno v:
PLoS Pathogens, Vol 19, Iss 11, p e1011841 (2023)
Macrophages play a key role in disseminated cryptococcosis, a deadly fungal disease caused by Cryptococcus neoformans. This opportunistic infection can arise following the reactivation of a poorly characterized latent infection attributed to dormant
Externí odkaz:
https://doaj.org/article/8451a509f1124967828dec79d6589389
Autor:
Raffael Júnio Araújo de Castro, Marco Túlio Aidar Mariano Rêgo, Fabiana S. Brandão, Ana Laura Alfonso Pérez, Janice Lisboa De Marco, Marcio José Poças-Fonseca, Connie Nichols, J. Andrew Alspaugh, Maria Sueli S. Felipe, Alexandre Alanio, Anamélia Lorenzetti Bocca, Larissa Fernandes
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT Cryptococcus neoformans is an opportunistic fungal pathogen known for its remarkable ability to infect and subvert phagocytes. This ability provides survival and persistence within the host and relies on phenotypic plasticity. The viable but
Externí odkaz:
https://doaj.org/article/504b6a0303ed44faaefaa6fd3e93a753
Autor:
Lucas de Oliveira Las-Casas, Clara Luna Freitas Marina, Raffael Júnio Araújo de Castro, Luísa Coutinho Coelho, Sônia Nair Báo, G. Sybren de Hoog, Vânia Aparecida Vicente, Larissa Fernandes, Anamelia Lorenzetti Bocca
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Chromoblastomycosis (CBM) is a chronic cutaneous and subcutaneous mycosis caused by black, dimorphic, and filamentous fungi of the Herpothrichiellaceae family, such as species of the genus Fonsecaea. These fungi can switch between the saprophytic for
Externí odkaz:
https://doaj.org/article/8ac2f3e6d3954d0a8cf9f8babe1d1a0a
Autor:
Maria José Chiabai, Juliana Franco Almeida, Mariana Gabriela Dantas de Azevedo, Suelen Soares Fernandes, Vanessa Bastos Pereira, Raffael Júnio Araújo de Castro, Márcio Sousa Jerônimo, Isabel Garcia Sousa, Leonora Maciel de Souza Vianna, Anderson Miyoshi, Anamelia Lorenzetti Bocca, Andrea Queiroz Maranhão, Marcelo Macedo Brigido
Publikováno v:
BMC Biotechnology, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Anti-Tumor Necrosis Factor-alpha therapy has become clinically important for treating inflammatory bowel disease. However, the use of conventional immunotherapy requires a systemic exposure of patients and collateral side effects.
Externí odkaz:
https://doaj.org/article/0ec68aed5e3847a9b7f0506a0a7468e0
Autor:
Isaque Medeiros Siqueira, Marcel Wüthrich, Mengyi Li, Huafeng Wang, Lucas de Oliveira Las-Casas, Raffael Júnio Araújo de Castro, Bruce Klein, Anamelia Lorenzetti Bocca
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 6, p e0008386 (2020)
Chromoblastomycosis (CBM) is a chronic worldwide subcutaneous mycosis, caused by several dimorphic, pigmented dematiaceous fungi. It is difficult to treat patients with the disease, mainly because of its recalcitrant nature. The correct activation of
Externí odkaz:
https://doaj.org/article/8f16882f50844610b56bd1b0b734593c
Autor:
Paulo Henrique de Holanda Veloso Júnior, Karina Smidt Simon, Raffael Júnio Araújo de Castro, Luísa Coutinho Coelho, Fabián Andres Hurtado Erazo, Adolfo Carlos Barros de Souza, Rogério Coutinho das Neves, Viviane Furlan Lozano, Elizabeth Ferroni Schwartz, Aldo Henrique Tavares, Márcia Renata Mortari, Ana Paula Junqueira-Kipnis, Ildinete Silva-Pereira, Anamelia Lorenzetti Bocca
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 118, Iss , Pp - (2019)
Antimicrobial peptides (AMPs) are small molecules with microbicidal and immunoregulatory activities. In this study we evaluated the anti-inflammatory and antimicrobial activities of peptides ToAP3 and ToAP4, AMPs from the venom of the Brazilian scorp
Externí odkaz:
https://doaj.org/article/0ffb0ee4301a46d782215b0c99a0c77a
Autor:
Raffael Júnio Araújo de Castro, Isaque Medeiros Siqueira, Márcio Sousa Jerônimo, Angelina Maria Moreschi Basso, Paulo Henrique de Holanda Veloso Junior, Kelly Grace Magalhães, Luiza Chaves Leonhardt, Stephan Alberto Machado de Oliveira, Pedro Henrique Bürgel, Aldo Henrique Tavares, Anamélia Lorenzetti Bocca
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Fonsecaea pedrosoi is the main etiologic agent of chromoblastomycosis (CBM), one of the most prevalent subcutaneous mycosis in tropical and subtropical countries. CBM is a poorly characterized chronic infection that commonly starts after transcutaneo
Externí odkaz:
https://doaj.org/article/9b113ed1e4574eb18fd6510cd60abaed
Autor:
Isaque Medeiros Siqueira, Raffael Júnio Araújo de Castro, Luiza Chaves de Miranda Leonhardt, Márcio Sousa Jerônimo, Aluízio Carlos Soares, Tainá Raiol, Christiane Nishibe, Nalvo Almeida, Aldo Henrique Tavares, Christian Hoffmann, Anamelia Lorenzetti Bocca
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 3, p e0005461 (2017)
A common theme across multiple fungal pathogens is their ability to impair the establishment of a protective immune response. Although early inflammation is beneficial in containing the infection, an uncontrolled inflammatory response is detrimental
Externí odkaz:
https://doaj.org/article/a0c719b8bdaf4932a5f0f69279af272d
Autor:
Andréia Biolchi Mayer, Henrique de Oliveira Amaral, Danilo Gustavo Rodrigues de Oliveira, Gabriel Avohay Alves Campos, Priscilla Galante Ribeiro, Solange Cristina Rego Fernandes, Adolfo Carlos Barros de Souza, Raffael Júnio Araújo de Castro, Anamélia Lorenzetti Bocca, Márcia Renata Mortari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d32ec9d31597405f135dbe6a2a80bd83
https://doi.org/10.2139/ssrn.4388019
https://doi.org/10.2139/ssrn.4388019
Cryptococcus neoformans Secretes Small Molecules That Inhibit IL-1β Inflammasome-Dependent Secretion
Autor:
Joshua D. Nosanchuk, Aldo Henrique Tavares, Patrícia Albuquerque, Paulo Henrique de Holanda Veloso Janior, Robin C. May, Carolina Coelho, Arturo Casadevall, Pedro Henrique Viana Saavedra, Raffael Júnio Araújo de Castro, Ernesto S. Nakayasu, Clara Luna Marina, Pedro Henrique Bürgel, Stephan Alberto Machado de Oliveira, Heino M. Heyman, Anamélia Lorenzetti Bocca, Radames J. B. Cordero
Publikováno v:
Mediators of Inflammation
Mediators of Inflammation, Vol 2020 (2020)
Mediators of Inflammation, Vol 2020 (2020)
Cryptococcus neoformans is an encapsulated yeast that causes disease mainly in immunosuppressed hosts. It is considered a facultative intracellular pathogen because of its capacity to survive and replicate inside phagocytes, especially macrophages. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d53b2c263acae106b1124c8d39abd30a
http://europepmc.org/articles/PMC7748918
http://europepmc.org/articles/PMC7748918