Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Rafeeq P.H. Ahmed"'
Autor:
Ingrid F. Dos Santos, Charuhas V. Thakar, Rafeeq P.H. Ahmed, Sihame Amlal, Sulaiman Sheriff, Hassane Amlal
Publikováno v:
American Journal of Physiology-Renal Physiology. 316:F743-F757
Chronic adenine feeding is extensively used to develop animal models of chronic renal failure with metabolic features resembling those observed in humans. However, the mechanism by which adenine induces renal failure is poorly understood. In this stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a101792a2baeec1563e9d5921a2f582a
https://doi.org/10.1152/ajprenal.00142.2018
https://doi.org/10.1152/ajprenal.00142.2018
Autor:
Perwez Alam, Raghav Pandey, Michelle L. Nieman, Mohammed Arif, Yigang Wang, Sakthivel Sadayappan, Bryan D. Maliken, Rafeeq P.H. Ahmed, Bereket Haile, Miso Rokvic, Onur Kanisicak, Arghya Paul
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Myocardial infarction results in a large‐scale cardiomyocyte loss and heart failure due to subsequent pathological remodeling. Whereas zebrafish and neonatal mice have evident cardiomyocyte expansion following injury, adult mammalian car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5635155296460dfb0347b01b9b7c28e3
https://doi.org/10.1161/jaha.119.012089
https://doi.org/10.1161/jaha.119.012089
Publikováno v:
Nanoscale. 8:7371-7376
A nanocomposite hydrogel with photocrosslinkable micro-porous networks and a nanoclay component was successfully prepared to control the release of growth factor-rich stem cell secretome. The proven pro-angiogenic and cardioprotective potential of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5039932129b93ea5c72f5cd1d0641784
https://doi.org/10.1039/c5nr07806g
https://doi.org/10.1039/c5nr07806g
Publikováno v:
Circulation Research. 123
Rationale: Stem cells are constantly exposed to biomechanical and biochemical signals when transplanted in a continuously beating cardiac environment for treatment. Here, we postulated that an in vitro miniaturized beating cardiac microenvironment ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010925d39d27b93d1f35cafea03292d1
https://doi.org/10.1161/res.123.suppl_1.339
https://doi.org/10.1161/res.123.suppl_1.339
Autor:
Arghya Paul, Perwez Alam, Aparna R. Chakravarti, Settimio Pacelli, Andras Czirok, Saman Modaresi, Rafeeq P.H. Ahmed, Samik Bagchi
INTRODUCTION: Stem cell-based therapies represent a valid approach to restore cardiac function due to their beneficial effect in reducing scar area formation and promoting angiogenesis. However, their translation into the clinic is limited by the poo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c81deb41abb52dc9229fe440a2b8b80f
https://europepmc.org/articles/PMC6774647/
https://europepmc.org/articles/PMC6774647/
Autor:
Shujia Jiang, Raghav Pandey, Perwez Alam, Arghya Paul, Mohammed Arif, Rafeeq P.H. Ahmed, Sakthivel Sadayappan
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 95(12)
An innovative approach for cardiac regeneration following injury is to induce endogenous cardiomyocyte (CM) cell cycle re-entry. In the present study, CMs from adult rat hearts were isolated and transfected with cel-miR-67 (control) and rno-miR-210.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bec96454dd2a88720b33d33f20806d38
https://pubmed.ncbi.nlm.nih.gov/28948298
https://pubmed.ncbi.nlm.nih.gov/28948298
Publikováno v:
Cardiovascular regenerative medicine. 3
Cardiovascular disease has been the biggest killer in the United States for decades, with almost a million new cases each year. Even though mammalian rodent neonatal cardiomyocytes show proliferative potential for up to 5 days, adult cardiomyocytes l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbdf0b138f0f25be57c5b42db62ce6f2
https://pubmed.ncbi.nlm.nih.gov/28111633
https://pubmed.ncbi.nlm.nih.gov/28111633
Autor:
Settimio Pacelli, Jonathan Whitlow, Aparna R. Chakravarti, Saheli Samanta, Saman Modaresi, Johnson Rajasingh, Rafeeq P.H. Ahmed, Francisca M. Acosta, Arghya Paul
Nanodiamonds (NDs) represent an emerging class of carbon nanomaterials that possess favorable physical and chemical properties to be used as multifunctional carriers for a variety of bioactive molecules. Here we report the synthesis and characterizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33757cd92236e4dc629eff43b28f846
http://hdl.handle.net/11573/1043515
http://hdl.handle.net/11573/1043515
Publikováno v:
Stem Cells and Development. 21:1769-1778
In continuation of a previous work that transgene expression of sonic hedgehog promoted neo-vascularization via netrin-1 release, the current study was aimed at assessing the anti-apoptotic and pro-angiogenic role of netrin-1 transgene overexpression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2dda1896bd073d309f8a1af9036ccd8
https://doi.org/10.1089/scd.2011.0475
https://doi.org/10.1089/scd.2011.0475
Autor:
Shujia Jiang, Muhammad Ashraf, Rafeeq P.H. Ahmed, Longhu Li, Stephanie Buccini, Husnain Kh Haider
Publikováno v:
Circulation Research. 109:60-70
Rationale: Skeletal myoblasts (SMs) with inherent myogenic properties are better candidates for reprogramming to pluripotency. Objective: To reprogram SMs to pluripotency and show that reprogrammed SMs (SiPS) express embryonic gene and microRNA profi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa4def9cc4bc4c40a4bb921109daf04c
https://doi.org/10.1161/circresaha.110.240010
https://doi.org/10.1161/circresaha.110.240010