Soft, stretchable, epidermal sensor with integrated electronics and photochemistry for measuring personal UV exposures.

Autor: Yunzhou Shi, Megan Manco, Dominique Moyal, Gil Huppert, Hitoshi Araki, Anthony Banks, Hemant Joshi, Richard McKenzie, Alex Seewald, Guy Griffin, Ellora Sen-Gupta, Donald Wright, Philippe Bastien, Florent Valceschini, Sophie Seité, John A Wright, Roozbeh Ghaffari, John Rogers, Guive Balooch, Rafal M Pielak

Publikováno v: PLoS ONE, Vol 13, Iss 1, p e0190233 (2018)

Excessive ultraviolet (UV) radiation induces acute and chronic effects on the skin, eye and immune system. Personalized monitoring of UV radiation is thus paramount to measure the extent of personal sun exposure, which could vary with environment, li

Externí odkaz: https://doaj.org/article/b75866e468d74892ae75348592c2f7bd

Direct single molecule measurement of TCR triggering by agonist pMHC in living primary T cells

Autor: Geoff P O'Donoghue, Rafal M Pielak, Alexander A Smoligovets, Jenny J Lin, Jay T Groves

Publikováno v: eLife, Vol 2 (2013)

T cells discriminate between self and foreign antigenic peptides, displayed on antigen presenting cell surfaces, via the TCR. While the molecular interactions between TCR and its ligands are well characterized in vitro, quantitative measurements of t

Externí odkaz: https://doaj.org/article/8c0ff3c12269470290cd9d2c204f613a

Analysis of bacteria using zero volt paper spray

Autor: Soumabha Bag, Rafal M. Pielak, Christopher J. Pulliam, R. Graham Cooks, Pu Wei, Dalton T. Snyder

Publikováno v: Analytical Methods. 8:1770-1773

The application of zero volt paper spray to the discrimination between species of bacteria is demonstrated here. While absolute signal intensities of representative lipids from bacterial membranes were three orders of magnitude lower than for convent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f7eab748281350516875e642df74b776
https://doi.org/10.1039/c6ay00063k

Early T cell receptor signals globally modulate ligand:receptor affinities during antigen discrimination

Autor: Nicole C. Fay, Shalini T. Low-Nam, Geoff P. O’Donoghue, Rafal M. Pielak, Jenny J. Lin, Jay T. Groves, Katherine N. Alfieri

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, vol 114, iss 46

Significance Antigen discrimination by T cells is based on subtle differences in binding of the T cell receptor (TCR) for its peptide major histocompatibility complex (pMHC) ligand. While such binding characteristics are readily mapped with great pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e663e557ce350908ed09021d4e7e129
https://pubmed.ncbi.nlm.nih.gov/29087297

Soft, stretchable, epidermal sensor with integrated electronics and photochemistry for measuring personal UV exposures

Autor: Hitoshi Araki, Richard McKenzie, Guive Balooch, Philippe Bastien, Rafal M. Pielak, John A. Rogers, Megan Manco, Gil Huppert, Alex Seewald, Yunzhou Shi, Dominique Moyal, Ellora Sen-Gupta, Donald E. Wright, John A. Wright, Sophie Seite, Guy Griffin, Anthony Banks, Roozbeh Ghaffari, Joshi Hemant, Florent Valceschini

Publikováno v: PLoS ONE
PLoS ONE, Vol 13, Iss 1, p e0190233 (2018)

Excessive ultraviolet (UV) radiation induces acute and chronic effects on the skin, eye and immune system. Personalized monitoring of UV radiation is thus paramount to measure the extent of personal sun exposure, which could vary with environment, li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f04a47ff34a25a3b1a0e94447bd6a0d
https://pubmed.ncbi.nlm.nih.gov/29293664