Výsledky vyhledávání - "Rafal Fudala"

Akademický článek

Photophysical Characterization and In Vitro Evaluation of α-Mangostin-Loaded HDL Mimetic Nano-Complex in LN-229 Glioblastoma Spheroid Model

Autor: Ammar Kapic, Nirupama Sabnis, Akpedje S. Dossou, Jose Chavez, Luca Ceresa, Zygmunt Gryczynski, Rafal Fudala, Rob Dickerman, Bruce A. Bunnell, Andras G. Lacko

Publikováno v: International Journal of Molecular Sciences, Vol 25, Iss 13, p 7378 (2024)

Cytotoxic activity has been reported for the xanthone α-mangostin (AMN) against Glioblastoma multiforme (GBM), an aggressive malignant brain cancer with a poor prognosis. Recognizing that AMN’s high degree of hydrophobicity is likely to limit its

Externí odkaz: https://doaj.org/article/6df530a7c23e48dba91237e10c1a0b0e

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Mannose-functionalization of reconstituted high-density lipoprotein nanoparticles improves payload delivery and enhances M2-to-M1 phenotype reprogramming of RAW 264.7 macrophages polarized by B16-F10 melanoma cells

Autor: Akpedje S. Dossou, Morgan E. Mantsch, Nirupama Sabnis, Rance E. Berg, Rafal Fudala, Andras G. Lacko

Publikováno v: Frontiers in Drug Delivery, Vol 3 (2023)

The targeting and conversion of the immunosuppressive (M2) tumor-associated macrophages (TAMs) to an immunostimulatory (M1) phenotype can induce tumor regression in advanced melanoma. We have previously characterized and reported the ability of recon

Externí odkaz: https://doaj.org/article/5ff5550d4dbd4be3b81c0f0a7d67127a

Zobrazit plný text záznamu

Akademický článek

Mannose-Coated Reconstituted Lipoprotein Nanoparticles for the Targeting of Tumor-Associated Macrophages: Optimization, Characterization, and In Vitro Evaluation of Effectiveness

Autor: Akpedje S. Dossou, Morgan E. Mantsch, Ammar Kapic, William L. Burnett, Nirupama Sabnis, Jeffery L. Coffer, Rance E. Berg, Rafal Fudala, Andras G. Lacko

Publikováno v: Pharmaceutics, Vol 15, Iss 6, p 1685 (2023)

Reconstituted high-density lipoprotein nanoparticles (rHDL NPs) have been utilized as delivery vehicles to a variety of targets, including cancer cells. However, the modification of rHDL NPs for the targeting of the pro-tumoral tumor-associated macro

Externí odkaz: https://doaj.org/article/a3561ba120124d11868c3fd6d86ea3e6

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Novel Use of Hypoxia-Inducible Polymerizable Protein to Augment Chemotherapy for Pancreatic Cancer

Autor: Andrew Gdowski, Hamed Hayatshahi, Rafal Fudala, Rohan Joshi, Jin Liu, Jamboor K. Vishwanatha, Rohan Jeyarajah, Paul Guzik, Amalendu P. Ranjan

Publikováno v: Pharmaceutics, Vol 14, Iss 1, p 128 (2022)

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive malignancies and is the fourth leading cause of cancer-related deaths in the United States. Unfortunately, 80–85% of patients are diagnosed with unresectable, advanced stage tumo

Externí odkaz: https://doaj.org/article/d6f5db35a60d47868cc43803e8a15a02

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

No Difference in Myosin Kinetics and Spatial Distribution of the Lever Arm in the Left and Right Ventricles of Human Hearts

Autor: Divya Duggal, S. Requena, Janhavi Nagwekar, Sangram Raut, Ryan Rich, Hriday Das, Vipul Patel, Ignacy Gryczynski, Rafal Fudala, Zygmunt Gryczynski, Cheavar Blair, Kenneth S. Campbell, Julian Borejdo

Publikováno v: Frontiers in Physiology, Vol 8 (2017)

The systemic circulation offers larger resistance to the blood flow than the pulmonary system. Consequently, the left ventricle (LV) must pump blood with more force than the right ventricle (RV). The question arises whether the stronger pumping actio

Externí odkaz: https://doaj.org/article/b17fdee6dfc149008598a180de7cc148

Zobrazit plný text záznamu

Akademický článek

Long-lived bright red emitting azaoxa-triangulenium fluorophores.

Autor: Badri P Maliwal, Rafal Fudala, Sangram Raut, Rutika Kokate, Thomas J Sørensen, Bo W Laursen, Zygmunt Gryczynski, Ignacy Gryczynski

Publikováno v: PLoS ONE, Vol 8, Iss 5, p e63043 (2013)

The fluorescence lifetimes of most red emitting organic probes are under 4 nanoseconds, which is a limiting factor in studying interactions and conformational dynamics of macromolecules. In addition, the nanosecond background autofluorescence is a si

Externí odkaz: https://doaj.org/article/7e16835107f64f7ea4ef417c3e35cc61

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání