Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Rafal, Tokarz"'
Autor:
Santiago Sanchez-Vicente, Rafal Tokarz
Publikováno v:
Pathogens, Vol 12, Iss 11, p 1371 (2023)
Co-infections are a poorly understood aspect of tick-borne diseases. In the United States alone, nineteen different tick-borne pathogens have been identified. The majority of these agents are transmitted by only two tick species, Ixodes scapularis an
Externí odkaz:
https://doaj.org/article/73a10651897a40b6b649f63c6ed3bdaa
Autor:
André A. Grassmann, Rafal Tokarz, Caroline Golino, Melissa A. McLain, Ashley M. Groshong, Justin D. Radolf, Melissa J. Caimano
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 5 (2023)
The RNA polymerase alternative σ factor RpoS in Borrelia burgdorferi (Bb), the Lyme disease pathogen, is responsible for programmatic-positive and -negative gene regulation essential for the spirochete’s dual-host enzootic cycle. RpoS is expressed
Externí odkaz:
https://doaj.org/article/7011e835d2e8466aab6aa4a0dd6c4517
Autor:
Matthew J. Cummings, Barnabas Bakamutumaho, Adam Price, Nicholas Owor, John Kayiwa, Joyce Namulondo, Timothy Byaruhanga, Moses Muwanga, Christopher Nsereko, Stephen Sameroff, Rafal Tokarz, Wai Wong, Shivang S. Shah, Michelle H. Larsen, W. Ian Lipkin, Julius J. Lutwama, Max R. O’Donnell
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-15 (2022)
Abstract Background The global burden of sepsis is concentrated in sub-Saharan Africa, where severe infections disproportionately affect young, HIV-infected adults and high-burden pathogens are unique. In this context, poor understanding of sepsis im
Externí odkaz:
https://doaj.org/article/733096a2fb53498da73010f99b9ffb32
Autor:
Komal Jain, Teresa Tagliafierro, Adriana Marques, Santiago Sanchez-Vicente, Alper Gokden, Brian Fallon, Nischay Mishra, Thomas Briese, Vishal Kapoor, Stephen Sameroff, Cheng Guo, Luis A. Marcos, Linden Hu, W. Ian Lipkin, Rafal Tokarz
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Inadequate sensitivity has been the primary limitation for implementing high-throughput sequencing for studies of tick-borne agents. Here we describe the development of TBDCapSeq, a sequencing assay that uses hybridization capture probes tha
Externí odkaz:
https://doaj.org/article/dbd846340ea64ae88cdea56825636c91
Autor:
Nischay Mishra, Xi Huang, Shreyas Joshi, Cheng Guo, James Ng, Riddhi Thakkar, Yongjian Wu, Xin Dong, Qianlin Li, Richard S. Pinapati, Eric Sullivan, Adrian Caciula, Rafal Tokarz, Thomas Briese, Jiahai Lu, W. Ian Lipkin
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-7 (2021)
Mishra, Huang et al. identify 29 linear SARS-CoV-2 epitopes that are immunoreactive with the plasma from individuals who had asymptomatic, mild, or severe SARS-CoV-2 infections. This study suggests the possibility of using these peptides to discrimin
Externí odkaz:
https://doaj.org/article/d6d4997c661440319c0d9efbc22cb7b2
Autor:
Santiago Sanchez-Vicente, Komal Jain, Teresa Tagliafierro, Alper Gokden, Vishal Kapoor, Cheng Guo, Elizabeth J. Horn, W. Ian Lipkin, Rafal Tokarz
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Assay sensitivity can be a limiting factor in the use of PCR as a tool for the detection of tick-borne pathogens in blood. We evaluated the performance of Tick-borne disease Capture Sequencing Assay (TBDCapSeq), a capture sequencing assay targeting t
Externí odkaz:
https://doaj.org/article/21e8c0f369f441f1abb92ad80a172945
Publikováno v:
Parasites & Vectors, Vol 13, Iss 1, Pp 1-4 (2020)
Abstract Background Metagenomic studies have revealed the presence of a filarial nematode in Ixodes scapularis. The phylogeny of this agent, and its potential for human infection, are unknown. Methods We used existing metagenomic data from I. scapula
Externí odkaz:
https://doaj.org/article/9c270e5ae416480783a2c78f1f870158
Autor:
Matthew J. Cummings, Barnabas Bakamutumaho, Komal Jain, Adam Price, Nicholas Owor, John Kayiwa, Joyce Namulondo, Timothy Byaruhanga, Moses Muwanga, Christopher Nsereko, Irene Nayiga, Stephen Kyebambe, Xiaoyu Che, Stephen Sameroff, Rafal Tokarz, Wai Wong, Thomas S. Postler, Michelle H. Larsen, W. Ian Lipkin, Julius J. Lutwama, Max R. O'Donnell
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 93:79-85
Autor:
Stephen Sameroff, Rafal Tokarz, Roxanne Albertha Charles, Komal Jain, Alexandra Oleynik, Xiaoyu Che, Karla Georges, Christine V. Carrington, W. Ian Lipkin, Chris Oura
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract Ticks are vectors of a wide variety of pathogens that are implicated in mild to severe disease in humans and other animals. Nonetheless, the full range of tick-borne pathogens is unknown. Viruses, in particular, have been neglected in discov
Externí odkaz:
https://doaj.org/article/0713cb275449466293e3219211c4a4d6
Autor:
Stephen Sameroff, Rafal Tokarz, Marko Vucelja, Komal Jain, Alexandra Oleynik, Marko Boljfetić, Linda Bjedov, Rachel A. Yates, Josip Margaletić, Christopher A. L. Oura, Walter Ian Lipkin, Lidija Cvetko Krajinović, Alemka Markotić
Publikováno v:
Viruses, Vol 14, Iss 5, p 929 (2022)
Tick-borne diseases are a serious threat to both public and veterinary health. In this study, we used high-throughput sequencing to characterize the virome of three tick species implicated in the spread of vector-borne disease throughout Croatia. Ten
Externí odkaz:
https://doaj.org/article/9f528aed9f844df69b025d92ceb4a95f