Výsledky vyhledávání - "Rafaela de Oliveira Benatti"

Akademický článek

Identification of common and divergent gene expression signatures in patients with venous and arterial thrombosis using data from public repositories.

Autor: Bidossessi Wilfried Hounkpe, Rafaela de Oliveira Benatti, Benilton de Sá Carvalho, Erich Vinicius De Paula

Publikováno v: PLoS ONE, Vol 15, Iss 8, p e0235501 (2020)

STRENGTHS AND LIMITATIONS OF THIS STUDY:Our results represent the first comparison of venous and arterial thrombosis at the transcriptomic level.Our main result was the demonstration that immunothrombosis pathways are important to the pathophysiology

Externí odkaz: https://doaj.org/article/fcdd06665cf44d12bbfddbdeaaf75d45

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Identification of common and divergent gene expression signatures in patients with venous and arterial thrombosis using data from public repositories

Autor: Erich Vinicius De Paula, Rafaela de Oliveira Benatti, Bidossessi Wilfried Hounkpe, Benilton S. Carvalho

Publikováno v: PLoS ONE, Vol 15, Iss 8, p e0235501 (2020)
PLoS ONE

Cardiovascular disease (CVD) and venous thromboembolism (VTE) figure among the main causes of morbidity and mortality in modern societies. Although associated with distinct pathogenic mechanisms, epidemiological, experimental and clinical trial data

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::735e219485c957bb1b2facd5f4dc5b78
https://doaj.org/article/fcdd06665cf44d12bbfddbdeaaf75d45

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Role of innate immunity-triggered pathways in the pathogenesis of Sickle Cell Disease: a meta-analysis of gene expression studies

Autor: Magnun N. N. Santos, Sara Teresinha Olalla Saad, Marina Pereira Colella, Maiara Marx Luz Fiusa, Fernando Ferreira Costa, Rafaela de Oliveira Benatti, Bidossessi Wilfried Hounkpe, Loredana Nilkenes Gomes da Costa, Erich Vinicius De Paula

Publikováno v: Scientific Reports

Despite the detailed characterization of the inflammatory and endothelial changes observed in Sickle Cell Disease (SCD), the hierarchical relationship between elements involved in the pathogenesis of this complex disease is yet to be described. Meta-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd7b1887b0da0a3af166820c13365f2c
https://doi.org/10.1038/srep17822

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On the Links between Arterial and Venous Thrombosis: A Comparative Genomic Analysis of Cardiovascular Disease and Venous Thromboembolism

Autor: Benilton S. Carvalho, Rafaela de Oliveira Benatti, Bidossessi Wilfried Hounkpe, Erich Vinicius De Paula

Publikováno v: Blood. 132:3807-3807

Background: The formation of thrombi inside arteries and veins is a process that underlies the pathogenesis of the most important causes of morbidity and mortality in the modern world: namely cardiovascular diseases (CVD), a term encompassing acute m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6ac6bffd2be17e04533dabc3d00ebdab
https://doi.org/10.1182/blood-2018-99-110719

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Maternal high-fat diet consumption modulates hepatic lipid metabolism and microRNA-122 (miR-122) and microRNA-370 (miR-370) expression in offspring

Autor: Marcio Alberto Torsoni, Licio A. Velloso, Marciane Milanski, Laís Angélica de Paula Simino, Arine M. Melo, Adriana Souza Torsoni, Fernanda Oliveira Borges, Rafaela de Oliveira Benatti, Letícia M. Ignacio-Souza

Publikováno v: The British journal of nutrition. 111(12)

Maternal consumption of a high-fat diet (HFD) during pregnancy and lactation is closely related to hepatic lipid accumulation, insulin resistance and increased serum cytokine levels in offspring and into their adulthood. MicroRNA (miRNA) have been im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86c9c5fa0e8c5ed9253c04225375fe37
https://pubmed.ncbi.nlm.nih.gov/24666709

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Hypothalamic endoplasmic reticulum stress and insulin resistance in offspring of mice dams fed high-fat diet during pregnancy and lactation

Autor: Licio A. Velloso, Adriana Souza Torsoni, Caroline Okino, Rafaela de Oliveira Benatti, Arine M. Melo, Marcio Alberto Torsoni, Letícia M. Ignacio-Souza, Marciane Milanski

Publikováno v: Metabolism: clinical and experimental. 63(5)

Objective The goal of this study was to determine the presence early of markers of endoplasmic reticulum stress (ERS) and insulin resistance in the offspring from dams fed HFD (HFD-O) or standard chow diet (SC-O) during pregnancy and lactation. Mater

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20f0d90dffb2204c97b7f8d039f2317b
https://pubmed.ncbi.nlm.nih.gov/24636055

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A Meta-Analysis of Gene Expression Studies Highlights the Role of Innate Immunity in the Pathogenesis of Sickle Cell Disease and Reveals Novel Potential Regulators at the Transcriptomic Level

Autor: Magnun N. N. Santos, Maiara Marx Luz Fiusa, Erich Vinicius De Paula, Sara Terezinha Olalla Saad, Rafaela de Oliveira Benatti, Marina Pereira Colella, Fernando Ferreira Costa, Bidossessi Wilfried Hounkpe, Loredana Nilkenes Gomes da Costa

Publikováno v: Blood. 126:4578-4578

Sickle cell disease (SCD) is characterized by chronic inflammation and multisystem tissue damage. Despite the detailed characterization of the inflammatory changes observed in these patients, the precise identity of their critical triggers, as well a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::82358164dfdf4c9abb0f403a19aed295
https://doi.org/10.1182/blood.v126.23.4578.4578

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