Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Rafaela Scalco Ferreira"'
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Akademický článek
Study of the correlation between blood cholinesterases activity, urinary dialkyl phosphates, and the frequency of micronucleated polychromatic erythrocytes in rats exposed to disulfoton
Autor: Mariane Gonçalves Santos, Ricardo Vilela Vitor, Maurício Gustavo Nakamura, Luana de Souza Morelini, Rafaela Scalco Ferreira, Alexandre Giusti Paiva, Luciana Azevedo, Vanessa Bergamin Boralli Marques, Isarita Martins, Eduardo Costa Figueiredo
Publikováno v: Brazilian Journal of Pharmaceutical Sciences, Vol 49, Iss 1, Pp 149-154 (2013)
Organophosphates (OPs) are widely used as pesticides, and its urinary metabolites as well as the blood cholinesterases (ChEs) activity have been reported as possible biomarkers for the assessment of this pesticide exposure. Moreover, the OPs can indu
Externí odkaz: https://doaj.org/article/0fcda4a9be40410496a17637cfb554c2
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2
Overview of cisplatin-induced neurotoxicity and ototoxicity, and the protective agents
Autor: Neife Aparecida Guinaim dos Santos, Rafaela Scalco Ferreira, Antonio Cardozo dos Santos
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Cisplatin has dramatically improved the survival rate of cancer patients, but it has also increased the prevalence of hearing and neurological deficits in this population. Cisplatin induces ototoxicity, peripheral (most prevalent) and central (rare)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::217b3c46618512f8b970e2990bc011f7
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3
A synthetic snake-venom-based tripeptide (Glu-Val-Trp) protects PC12 cells from MPP + toxicity by activating the NGF-signaling pathway
Autor: Carolina P. Bernardes, Rafaela Scalco Ferreira, Eduardo Maffud Cilli, Suely Vilela Sampaio, Adélia Cristina Oliveira Cintra, Neife Aparecida Guinaim dos Santos, Norival A. Santos-Filho, Antonio Cardozo dos Santos, Flávia Malvestio Sisti
Publikováno v: Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2018-11-26T22:38:12Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-06-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Con
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84820fd1fe44bfa719347762a8f28e5b
https://doi.org/10.1016/j.peptides.2018.04.012
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4
Caffeic Acid Phenethyl Ester (CAPE) Protects PC12 Cells from Cisplatin-Induced Neurotoxicity by Activating the NGF-Signaling Pathway
Autor: Laís Silva Fernandes, Nádia Maria Martins, Antonio Cardozo dos Santos, Neife Aparecida Guinaim dos Santos, Rafaela Scalco Ferreira
Publikováno v: Neurotoxicity Research. 34:32-46
Cisplatin is a highly effective chemotherapeutic drug that is toxic to the peripheral nervous system. Findings suggest that axons are early targets of the neurotoxicity of cisplatin. Although many compounds have been reported as neuroprotective, ther
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::157a4b270e7f902aaa4a58f4c25e35be
https://doi.org/10.1007/s12640-017-9849-z
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5
Caffeic Acid Phenethyl Ester (CAPE) protects PC12 cells against cisplatin-induced neurotoxicity by activating the AMPK/SIRT1, MAPK/Erk, and PI3k/Akt signaling pathways
Autor: Rafaela Scalco Ferreira, Andréia Cristina Karklin Fontana, Lilian do Amaral, Antonio Cardozo dos Santos, Carolina P. Bernardes, Neife Aparecida Guinaim dos Santos, Flávia Malvestio Sisti
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Peripheral sensory neuropathy (PSN) is a well-known side effect of cisplatin characterized by axonal damage. In the early stage of neurotoxicity, cisplatin affects proteins that modulate neurite outgrowth and neuroplasticity, without inducing mitocho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07beeb4cbab14b1cc4f576a77d29c5a9
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6
Peripheral sensory neuropathy induced by cisplatin: study of the mechanisms of neurotoxicity of cisplatin and the protective effect of caffeic acid phenethyl ester (CAPE) on PC12 cells
Autor: Rafaela Scalco Ferreira
Publikováno v: Biblioteca Digital de Teses e Dissertações da USP
Universidade de São Paulo (USP)
instacron:USP
Cisplatina é um agente quimioterápico altamente eficaz utilizado no tratamento de vários tipos de câncer. No entanto, seu uso clínico é limitado por ser o mais neurotóxico entre os derivados de platina. A neuropatia sensorial periférica induz
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16745e4116795967b0c534207f1c2ff8
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7
The neuroprotection of cannabidiol against MPP + -induced toxicity in PC12 cells involves trkA receptors, upregulation of axonal and synaptic proteins, neuritogenesis, and might be relevant to Parkinson's disease
Autor: Rafaela Scalco Ferreira, Antonio Cardozo dos Santos, Flávia Malvestio Sisti, Nádia Maria Martins, Laís Silva Fernandes, Regina Helena Costa Queiroz, Neife Aparecida Guinaim dos Santos
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Cannabidiol (CBD) is a non-psychoactive constituent of Cannabis sativa with potential to treat neurodegenerative diseases. Its neuroprotection has been mainly associated with anti-inflammatory and antioxidant events; however, other mechanisms might b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::154ff935ee6b2c60cc31609bc54b8c0d
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8
Caffeic acid phenethyl ester (CAPE) protects PC12 cells from MPP+ toxicity by inducing the expression of neuron-typical proteins
Autor: Rafaela Scalco Ferreira, Roberto de Barros Silva, Flávia Malvestio Sisti, Antonio Cardozo dos Santos, Nádia Maria Martins, Neife Aparecida Guinaim dos Santos
Publikováno v: NeuroToxicology. 45:131-138
Neurite loss is an early event in neurodegenerative diseases; therefore, the regeneration of the network of neurites constitutes an interesting strategy of treatment for such disorders. Neurotrophic factors play a critical role in neuronal regenerati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebde9f0578b369db1b29b1f69e04b040
https://doi.org/10.1016/j.neuro.2014.09.007
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9
The cannabinoid beta-caryophyllene (BCP) induces neuritogenesis in PC12 cells by a cannabinoid-receptor-independent mechanism
Autor: Nádia Maria Martins, Flávia Malvestio Sisti, Neife Aparecida Guinaim dos Santos, Osvaldo de Freitas, Laís Silva Fernandes, Antonio Cardozo dos Santos, Rafaela Scalco Ferreira
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Beta-caryophyllene (BCP) is a phytocannabinoid whose neuroprotective activity has been mainly associated with selective activation of cannabinoid-type-2 (CB2) receptors, inhibition of microglial activation and decrease of inflammation. Here, we addre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e49b03a84200a6770ff54d429f506d6
https://pubmed.ncbi.nlm.nih.gov/27871898
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10
High concentration of trichlorfon (1mM) disrupts axonal cytoskeleton and decreases the expression of plasticity-related proteins in SH-SY5Y cells
Autor: Antonio Cardozo dos Santos, Rafaela Scalco Ferreira, Laís Silva Fernandes, Neife Aparecida Guinaim dos Santos, Guilherme Luz Emerick
Publikováno v: Toxicology in vitro : an international journal published in association with BIBRA. 39
Some organophosphorus compounds (OPs) induce a neurodegenerative disorder known as organophosphate-induced delayed neuropathy (OPIDN), which is related to irreversible inhibition of neuropathy target esterase (NTE) and impairment of neurite outgrowth
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47d4a05c7332cf16b49a5ffd64a03d0a
https://pubmed.ncbi.nlm.nih.gov/27939611
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