Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Rafaela Sachetto Fernandes"'
Autor:
Gabriela Dias Noske, Yun Song, Rafaela Sachetto Fernandes, Rod Chalk, Haitem Elmassoudi, Lizbé Koekemoer, C. David Owen, Tarick J. El-Baba, Carol V. Robinson, The COVID Moonshot Consortium, Glaucius Oliva, Andre Schutzer Godoy
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
The Main protease of SARS-CoV-2 is key for viral replication, but its maturation process is still not completely understood. Here, the authors not only reveal unique details from the first step of maturation, but also demonstrate how different classe
Externí odkaz:
https://doaj.org/article/42ae45687cae484c842b30be8eac947b
Autor:
Leonardo Paiva Farias, Juliana Vitoriano-Souza, Lucas Esteves Cardozo, Leonardo Dos Reis Gama, Youvika Singh, Patrícia Aoki Miyasato, Giulliana Tessarin Almeida, Dunia Rodriguez, Mayra Mara Ferrari Barbosa, Rafaela Sachetto Fernandes, Tereza Cristina Barbosa, Almiro Pires da Silva Neto, Eliana Nakano, Paulo Lee Ho, Sergio Verjovski-Almeida, Helder Imoto Nakaya, Robert Alan Wilson, Luciana Cezar de Cerqueira Leite
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
In spite of several decades of research, an effective vaccine against schistosomiasis remains elusive. The radiation-attenuated (RA) cercarial vaccine is still the best model eliciting high protection levels, although the immune mechanisms have not y
Externí odkaz:
https://doaj.org/article/86e46c7f65814a33929f2c9a4e253239
Autor:
Mohammad Sadraeian, Fabio Francisco Pinto Junior, Marcela Miranda, Juliana Galinskas, Rafaela Sachetto Fernandes, Edgar Ferreira da Cruz, Libing Fu, Le Zhang, Ricardo Sobhie Diaz, Gustavo Cabral-Miranda, Francisco Eduardo Gontijo Guimarães
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 683 (2022)
Different light-based strategies have been investigated to inactivate viruses. Herein, we developed an HIV-based pseudotyped model of SARS-CoV-2 (SC2) to study the mechanisms of virus inactivation by using two different strategies; photoinactivation
Externí odkaz:
https://doaj.org/article/a2ef4f5dac0c47e7b33282b158a205e1
Autor:
Rafaela Sachetto Fernandes, Tereza Cristina Barbosa, Mayra Mara Ferrari Barbosa, Patrícia Aoki Miyasato, Eliana Nakano, Luciana Cezar Cerqueira Leite, Leonardo Paiva Farias
Publikováno v:
Parasites & Vectors, Vol 10, Iss 1, Pp 1-13 (2017)
Abstract Background Schistosoma mansoni venom allergen-like protein (SmVAL) is a gene family composed of 29 members divided into group 1 encoding proteins potentially secreted, and group 2 encoding intracellular components. Some members were found to
Externí odkaz:
https://doaj.org/article/6289e7a3a15f48fcaf70b2516a03626d
Autor:
Rafaela Sachetto Fernandes
Publikováno v:
Biblioteca Digital de Teses e Dissertações da USPUniversidade de São PauloUSP.
A esquistossomose é uma doença causada por trematódeos do gênero Schistosoma. Dentre os genes identificados no transcriptoma do parasita, membros da família gênica SmVAL (Schistosoma mansoni Venom Allergen-Like) foram apontados como candidatos
Autor:
Andre Schutzer Godoy, Aline Minalli Nakamura, Alice Douangamath, Yun Song, Gabriela Dias Noske, Victor Oliveira Gawriljuk, Rafaela Sachetto Fernandes, Humberto D. Muniz Pereira, Ketllyn Irene Zagato Oliveira, Daren Fearon, Alexandre Dias, Tobias Krojer, Michael Fairhead, Alisa Powell, Louise Dunnet, Jose Brandao-Neto, Rachael Skyner, Rod Chalk, Frank von Delft, Dávid Bajusz, Miklós Bege, Anikó Borbás, György Miklós Keserű, Glaucius Oliva
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19). The NSP15 endoribonuclease enzyme, known as NendoU, is highly conserved and plays a critical role in the ability of the virus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa19458d20abf8b20e94d12cf6d7b5e8
https://doi.org/10.1101/2022.09.26.509485
https://doi.org/10.1101/2022.09.26.509485
Autor:
Gabriela Dias Noske, Ellen de Souza Silva, Mariana Ortiz de Godoy, Isabela Dolci, Rafaela Sachetto Fernandes, Rafael Victório Carvalho Guido, Peter Sjö, Glaucius Oliva, Andre Schutzer Godoy
SARS-CoV-2 is the causative agent of COVID-19. Mpro is the main viral protease, with a critical role in replication and, therefore, an attractive target for antiviral drug discovery. The clinically approved drug nirmatrelvir from Pfizer, and the clin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::702b82e61353f62666f51b0295c9b5cf
https://doi.org/10.1101/2022.08.31.506107
https://doi.org/10.1101/2022.08.31.506107
Autor:
Gabriela Dias Noske, Ellen de Souza Silva, Mariana Ortiz de Godoy, Isabela Dolci, Rafaela Sachetto Fernandes, Rafael Victório Carvalho Guido, Peter Sjö, Glaucius Oliva, Andre Schutzer Godoy
Publikováno v:
Journal of Biological Chemistry. 299:103004
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ecd04d631a7c2a8f42470cc01aec8d3
https://doi.org/10.1016/j.jbc.2023.103004
https://doi.org/10.1016/j.jbc.2023.103004
Autor:
Uriel Enrique Aquino Ruiz, Igor Andrade Santos, Victória Riquena Grosche, Rafaela Sachetto Fernandes, Andre Schutzer de Godoy, Jhoan David Aguillón Torres, Marjorie Caroline Liberato Cavalcanti Freire, Nathalya Cristina de Moraes Roso Mesquita, Marco Guevara-Vega, Nilson Nicolau-Junior, Robinson Sabino-Silva, Tiago Wilson Patriarca Mineo, Glaucius Oliva, Ana Carolina Gomes Jardim
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
The Chikungunya virus (CHIKV) causes Chikungunya fever, a disease characterized by symptoms such as arthralgia/polyarthralgia. Currently, there are no antiviral approved against CHIKV, emphasizing the need to develop novel therapies. The imidazonapht
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aa7d87c0783d14566348c5e27f9ec83
https://doi.org/10.1016/j.virusres.2022.199029
https://doi.org/10.1016/j.virusres.2022.199029