Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Rafaela C.R. Hell"'
A human TRPV1 genetic variant within the channel gating domain regulates pain sensitivity in rodents
Autor:
Shufang He, Vanessa O. Zambelli, Pritam Sinharoy, Laura Brabenec, Yang Bian, Freeborn Rwere, Rafaela C.R. Hell, Beatriz Stein Neto, Barbara Hung, Xuan Yu, Meng Zhao, Zhaofei Luo, Chao Wu, Lijun Xu, Katrin J. Svensson, Stacy L. McAllister, Creed M. Stary, Nana-Maria Wagner, Ye Zhang, Eric R. Gross
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 3 (2023)
Pain signals are relayed to the brain via a nociceptive system, and in rare cases, this nociceptive system contains genetic variants that can limit the pain response. Here, we questioned whether a human transient receptor potential vanilloid 1 (TRPV1
Externí odkaz:
https://doaj.org/article/37d0f51fb16d49a8b7cc88f9c3a78b93
A human TRPV1 genetic variant within the channel gating domain regulates pain sensitivity in rodents
Autor:
Shufang He, Vanessa O. Zambelli, Pritam Sinharoy, Laura Brabenec, Yang Bian, Freeborn Rwere, Rafaela C.R. Hell, Beatriz Stein Neto, Barbara Hung, Xuan Yu, Meng Zhao, Zhaofei Luo, Chao Wu, Lijun Xu, Katrin J. Svensson, Stacy L. McAllister, Creed M. Stary, Nana-Maria Wagner, Ye Zhang, Eric R. Gross
Publikováno v:
The Journal of clinical investigation.
Pain signals are relayed to the brain via a nociceptive system, and in rare situations, this nociceptive system contains genetic variants that can limit pain response. Here we questioned whether a human transient receptor potential vanilloid 1 (TRPV1
Autor:
Alexandre Leite Rodrigues de Oliveira, Mateus Vidigal de Castro, Gustavo Ferreira Simões, Rafaela C.R. Hell, André Luis Bombeiro
Publikováno v:
Neuroscience letters. 647
MHC-I molecules are involved in the antigenic presentation of cytosol-derived peptides to CD8T lymphocytes. In the nervous system, MHC-I expression is low to absent, occurring only during certain phases of development and aging or after injuries. The
Autor:
Gerluza Aparecida Borges Silva, Suzana C. C. C. Miranda, Rafaela C.R. Hell, Alfredo M. Goes, José B. Alves, M. D. Martins
Publikováno v:
Archives of Oral Biology. 56:1-15
Objective This study investigated the in vitro effects of a chitosan-gelatin scaffold on growth and osteogenic differentiation of rat bone marrow mesenchymal stem cells (BMMSCs) in three-dimensional (3D) cultures and evaluated the biomaterial biocomp
Autor:
Natalia M. Breyner, Luiza Carvalho, Inácio N. Peixoto Filho, Carolina B. Machado, Patricia Valério, Marivalda M. Pereira, Alfredo M. Goes, Rafaela C.R. Hell
Publikováno v:
Cells Tissues Organs. 191:119-128
Cartilage tissue has a poor capacity for self-repair, especially in the case of severe cartilage damage due to trauma or age-related degeneration. Cell-based tissue engineering using scaffolds has provided an option for the repair of cartilage tissue
Autor:
Rafaela C.R. Hell, Alexandre Leite Rodrigues de Oliveira, Miriam Maria Silva Costa, Alfredo M. Goes
Publikováno v:
Neurobiology of Disease, Vol 33, Iss 2, Pp 290-300 (2009)
The present study proposed to graft mesenchymal stem cells (MSCs), which continuously produce BDNF, into the spinal cord ventral horn, after ventral root avulsion. Neurotrophin expression was naturally achieved by culturing MSCs in an undifferentiate
Autor:
Alexandre Leite Rodrigues de Oliveira, Sheila C. Victorio, Rafaela C.R. Hell, Luciana Politti Cartarozzi
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 9, Iss 1, p 88 (2012)
Journal of Neuroinflammation, Vol 9, Iss 1, p 88 (2012)
Background The histocompatibility complex (MHC) class I expression in the central nervous system (CNS) regulates synaptic plasticity events during development and adult life. Its upregulation may be associated with events such as axotomy, cytokine ex
Autor:
Marivalda M. Pereira, Caryne M. Bertollo, Natália de Melo Ocarino, Alfredo M. Goes, Rogéria Serakides, Jankerle Neves Boeloni, Cristiane Rodrigues Correa, Juneo Freitas Silva, Rafaela C.R. Hell
Publikováno v:
Pathology, research and practice. 209(1)
The objective of this study was to verify the osteogenic potential of the bone marrow mesenchymal stem cells (MSCs) of ovariectomized and non-ovariectomized female rats with hypo- and hyperthyroidism. Sixty two-month-old female rats were assigned to
Autor:
Rafaela C.R. Hell, Rogéria Serakides, Natália de Melo Ocarino, Alfredo M. Goes, Jankerle Neves Boeloni, Juneo Freitas Silva
Publikováno v:
Arquivos Brasileiros de Endocrinologia & Metabologia, Volume: 55, Issue: 5, Pages: 339-344, Published: JUN 2011
Arquivos Brasileiros de Endocrinologia & Metabologia v.55 n.5 2011
Arquivos Brasileiros de Endocrinologia & Metabologia
Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
instacron:SBEM
Arquivos Brasileiros de Endocrinologia & Metabologia v.55 n.5 2011
Arquivos Brasileiros de Endocrinologia & Metabologia
Sociedade Brasileira de Endocrinologia e Metabologia (SBEM)
instacron:SBEM
OBJETIVO: O objetivo deste estudo foi avaliar o efeito da T3 na expressão da osteocalcina, osteopontina e colágeno I durante a diferenciação osteogênica das células-tronco mesenquimais (CTM). MATERIAIS E MÉTODOS: As células da medula óssea d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eeb4746f4f93e1e8a208fbaeb15a807
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302011000500007&lng=en&tlng=en
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27302011000500007&lng=en&tlng=en
Autor:
N.M. Ocarino, Renato L. Santos, Alfredo M. Goes, Rafaela C.R. Hell, Rogéria Serakides, Jankerle Neves Boeloni, Juneo Freitas Silva
Publikováno v:
Acta physiologica (Oxford, England). 205(2)
Aim: To examine whether physical activity increases osteogenic differentiation of bone marrow mesenchymal stem cells (BMMSCs) from adult rats compared with young rats. Methods: Eighteen female Wistar rats were divided into three groups and the follow