Zobrazeno 1 - 10
of 423
pro vyhledávání: '"Rafael Yuste"'
Publikováno v:
iScience, Vol 27, Iss 10, Pp 110884- (2024)
Summary: The propagation of action potentials along axons is traditionally considered reliable due to the high safety factor for axonal spike transmission. However, numerical simulations suggest that high-frequency spikes could fail to invade distal
Externí odkaz:
https://doaj.org/article/34e50ac66b3440ffbfd09a6061adc99d
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Neuronal ensembles are groups of neurons with correlated activity associated with sensory, motor, and behavioral functions. To explore how ensembles encode information, we investigated responses of visual cortical neurons in awake mice using
Externí odkaz:
https://doaj.org/article/f7903cc08f6d42b38a200bd05bed6276
Autor:
Alison Hanson, Raphael Reme, Noah Telerman, Wataru Yamamoto, Jean-Christophe Olivo-Marin, Thibault Lagache, Rafael Yuste
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract The ability to record every spike from every neuron in a behaving animal is one of the holy grails of neuroscience. Here, we report coming one step closer towards this goal with the development of an end-to-end pipeline that automatically tr
Externí odkaz:
https://doaj.org/article/7ed8df33156b42bdb39368c4bb5b7ac4
Autor:
Christian Hansel, Rafael Yuste
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Synaptic connectivity defines groups of neurons that engage in correlated activity during specific functional tasks. These co-active groups of neurons form ensembles, the operational units involved in, for example, sensory perception, motor coordinat
Externí odkaz:
https://doaj.org/article/b38ff46f159545bcb4e5288873eca146
Autor:
Nicola Masala, Manuel Mittag, Eleonora Ambrad Giovannetti, Darik A O'Neil, Fabian J Distler, Peter Rupprecht, Fritjof Helmchen, Rafael Yuste, Martin Fuhrmann, Heinz Beck, Michael Wenzel, Tony Kelly
Publikováno v:
eLife, Vol 13 (2024)
Genetically encoded calcium indicators (GECIs) such as GCaMP are invaluable tools in neuroscience to monitor neuronal activity using optical imaging. The viral transduction of GECIs is commonly used to target expression to specific brain regions, can
Externí odkaz:
https://doaj.org/article/b8900cde3cd141bbb3eac8eba698eaf9
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102543- (2023)
Summary: Neuronal ensembles are coordinated groups of neurons that serve as functional building blocks of neural circuits. Here, we present PatMap, a computational toolbox for identifying pattern-completion neurons, key trigger cells capable of react
Externí odkaz:
https://doaj.org/article/83f536bda84f475a87471998706b889b
Autor:
Wataru Yamamoto, Rafael Yuste
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102453- (2023)
Summary: The introduction of calcium imaging has rendered cnidarians, such as Hydra vulgaris, valuable model organisms for investigating neuronal activity and behavior. Here, we present a comprehensive protocol to image and manipulate neuronal activi
Externí odkaz:
https://doaj.org/article/888fba7ec29e4e999855f8ace55812df
Autor:
M. Angeles Rabadan, Estanislao Daniel De La Cruz, Sneha B. Rao, Yannan Chen, Cheng Gong, Gregg Crabtree, Bin Xu, Sander Markx, Joseph A. Gogos, Rafael Yuste, Raju Tomer
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Advances in 3D neuronal cultures have allowed unprecedented access to the mechanisms underlying brain diseases. This work describes the novel Modular Neuronal Network (MoNNet) system, which enables more complex studies of cortical neuronal ensemble d
Externí odkaz:
https://doaj.org/article/934a266f6252418989d515f45d582f77
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The authors present a geneticallyencoded voltage indicator to specifically measure subthreshold membrane potentials. They combine two-photon imaging of voltage and calcium to map epileptic seizures progression through cortical circuits.
Externí odkaz:
https://doaj.org/article/437f4492fe8d4f6cbe8858e62aeeda9f
Autor:
Jonathan R. Lovas, Rafael Yuste
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101504- (2022)
Summary: The remarkable regenerative abilities of the small cnidarian Hydra vulgaris include the capacity to reassemble itself after dissociation into individual cells. Here, we present a robust protocol for the dissociation and reaggregation of Hydr
Externí odkaz:
https://doaj.org/article/787541bee3cd4e39b470214ce3c78c25