Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Rafael S, Floriano"'
Autor:
Henrique Roman-Ramos, Álvaro R. B. Prieto-da-Silva, Humberto Dellê, Rafael S. Floriano, Lourdes Dias, Stephen Hyslop, Raphael Schezaro-Ramos, Denis Servent, Gilles Mourier, Jéssica Lopes de Oliveira, Douglas Edgard Lemes, Letícia V. Costa-Lotufo, Jane S. Oliveira, Milene Cristina Menezes, Regina P. Markus, Paulo Lee Ho
Publikováno v:
Toxins, Vol 16, Iss 4, p 164 (2024)
Coralsnakes (Micrurus spp.) are the only elapids found throughout the Americas. They are recognized for their highly neurotoxic venom, which is comprised of a wide variety of toxins, including the stable, low-mass toxins known as three-finger toxins
Externí odkaz:
https://doaj.org/article/fd3e0d560549473e91b837667bb67b21
Autor:
Pamella G. Gutierres, Diego R. Pereira, Nataly L. Vieira, Lilian F. Arantes, Nelson J. Silva, Kristian A. Torres-Bonilla, Stephen Hyslop, Karen Morais-Zani, Rosa M. B. Nogueira, Edward G. Rowan, Rafael S. Floriano
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Varespladib (VPL) was primarily developed to treat inflammatory disturbances associated with high levels of serum phospholipase A2 (PLA2). VPL has also demonstrated to be a potential antivenom support agent to prevent PLA2-dependent effects produced
Externí odkaz:
https://doaj.org/article/34f61b212fb147f69bb0d5fa3473d38b
Autor:
Jocimar de Souza, Isadora C.F. Oliveira, Edson H. Yoshida, Nathalia M. Cantuaria, José C. Cogo, Kristian A. Torres-Bonilla, Stephen Hyslop, Nelson J. Silva Junior, Rafael S. Floriano, José María Gutiérrez, Yoko Oshima-Franco
Publikováno v:
Toxicon. 214:54-61
Autor:
Matheus Z. Gaspar, Ana C. Yabunaka, Rosimeire Silva-Carvalho, Charles U. Nascimento, Rejane B. Brinholi, Elisangela O. Silva, Juliana R. Gerez, Nelson J. Silva, Kristian A. Torres-Bonilla, Stephen Hyslop, Francis L. Pacagnelli, Rafael S. Floriano
Publikováno v:
Cardiovascular Toxicology.
Autor:
Rosimeire Silva-Carvalho, Matheus Z. Gaspar, Luiz H.B. Quadros, Luís G.G. Lobo, Rogério Giuffrida, Cecília L. Santarém, Elisangela O. Silva, Juliana R. Gerez, Nelson J. Silva, Stephen Hyslop, Bruno Lomonte, Rafael S. Floriano
Publikováno v:
Toxicon : official journal of the International Society on Toxinology. 213
In this work, we reported the efficacy of a combination of Brazilian therapeutic coralsnake antivenom (CAV) and varespladib (phospholipase A
Autor:
Pamella G. Gutierres, Diego R. Pereira, Nataly L. Vieira, Lilian F. Arantes, Nelson J. Silva, Kristian A. Torres-Bonilla, Stephen Hyslop, Karen Morais-Zani, Rosa M. B. Nogueira, Edward G. Rowan, Rafael S. Floriano
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 12 (2022)
Frontiers in Pharmacology, Vol 12 (2022)
Varespladib (VPL) was primarily developed to treat inflammatory disturbances associated with high levels of serum phospholipase A2 (PLA2). VPL has also demonstrated to be a potential antivenom support agent to prevent PLA2-dependent effects produced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c7e357e7d9f10a7b59d78f69a916b6
https://strathprints.strath.ac.uk/79312/1/Gutierres_etal_FP_2021_Action_of_Varespladib_LY_315920_a_phospholipase_A2_inhibitor_on_the_enzymatic_coagulant_and_haemorrhagic_activities.pdf
https://strathprints.strath.ac.uk/79312/1/Gutierres_etal_FP_2021_Action_of_Varespladib_LY_315920_a_phospholipase_A2_inhibitor_on_the_enzymatic_coagulant_and_haemorrhagic_activities.pdf
Autor:
Rosimeire, Silva-Carvalho, Matheus Z, Gaspar, Luiz H B, Quadros, Luís G G, Lobo, Letícia M, Rogério, Najla T S, Santos, Maria C, Zerbinatti, Cecília L, Santarém, Elisangela O, Silva, Juliana R, Gerez, Nelson J, Silva, Bruno, Lomonte, Edward G, Rowan, Rafael S, Floriano
Publikováno v:
Toxicology letters. 356
In this study, we investigated the action of varespladib (VPL) alone or in combination with a coral snake antivenom (CAV) on the local and systemic effects induced by Micrurus corallinus venom in rats. Adult male Wistar rats were exposed to venom (1.
Autor:
Rafael J, Borges, Fábio F, Cardoso, Carlos A H, Fernandes, Thiago R, Dreyer, Delkia S, de Moraes, Rafael S, Floriano, Léa, Rodrigues-Simioni, Marcos R M, Fontes
Publikováno v:
Biochimica et biophysica acta. General subjects. 1861(1 Pt)
One of the main challenges in snakebite envenomation treatment is the development of stable, versatile and efficient anti-venom therapies. Local myotoxicity in accidents involving snakes from the Bothrops genus is still a consequence of serum therapy
Publikováno v:
Toxicology research. 3(6)
The cucurbituril family of drug delivery vehicles have been examined for their tissue specific toxicity using ex vivo models. Cucurbit[6]uril (CB[6]), cucurbit[7]uril (CB[7]) and the linear cucurbituril-derivative Motor2 were examined for their neuro