Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Rafael Pazinatto, Aguiar"'
Autor:
Rafael Pazinatto Aguiar, Lígia Mendes Soares, Mark Varney, Adrian Newman-Tancredi A, Humberto Milani, Jos Prickaerts, Rúbia Maria Weffort de Oliveira
Publikováno v:
Neurobiology of Aging, 124, 52-59. Elsevier Science
5-HT1A serotonin receptors may play a role in cognitive function changes related to advanced age. Here, we investigated the effects of acute and repeated treatment with NLX-101 (F15599), a postsynaptic 5-HT1A receptor-biased agonist, and F13714, a pr
Autor:
Luiz Alexandre Marques Wiirzler, Rafael Pazinatto Aguiar, Ciomar Aparecida Bersani-Amado, Carlos Alberto Velázquez-Martínez, Roberto Kenji Nakamura Cuman
Publikováno v:
Acta Scientiarum. Health Sciences, Vol 38, Iss 2 (2016)
Genome-wide gene expression profiling of cancers has consistently identified the FOXM1 as one of the most commonly upregulated genes in cancer cells that plays an essential role in the regulation of a wide spectrum of biological processes, including
Externí odkaz:
https://doaj.org/article/35df46ba4b6e4db8a652a40a7b597bb4
Autor:
Adrian Newman-Tancredi, Jos Prickaerts, Rafael Pazinatto Aguiar, Rúbia Maria Weffort de Oliveira
Publikováno v:
Progress in Neuro-Psychopharmacology & Biological Psychiatry, 109:110210. Elsevier Science
Cerebral ischemia due to stroke or cardiac arrest greatly affects daily functioning and the quality of life of patients and has a high socioeconomic impact due to the surge in their prevalence. Advances in the identification of an effective pharmacot
Autor:
Danielle Lazarin Bidóia, Karlos Eduardo Pianoski, Alisson Felipe Oliveira, Samara Mendes de Souza Melo, Davana S. Gonçalves, Franciele Queiroz Ames, Fávero Reisdorfer Paula, Fernanda A. Rosa, Hélito Volpato, Rafael Pazinatto Aguiar, Celso Vataru Nakamura, Sidnei Moura, Davi F. Back, Ciomar Aparecida Bersani-Amado, Michael J. V. da Silva, Andrey P. Jacomini
Publikováno v:
Bioorganicmedicinal chemistry. 28(12)
The inflammatory response is the reaction of living tissue to an injury of a foreign nature, such as infection and irritants, and occurs as part of the body's natural defence response. Compounds capable of inhibiting cyclooxygenase (COX) enzymes, esp
Autor:
Rafael Pazinatto, Aguiar, Lígia Mendes, Soares, Erika, Meyer, Fernanda Canova, da Silveira, Humberto, Milani, Adrian, Newman-Tancredi, Mark, Varney, Jos, Prickaerts, Rúbia M Weffort, Oliveira
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 99
Pharmacological interventions that selectively activate serotonin 5-hydroxytryptramine-1A (5-HT
Autor:
Luiz Alexandre Marques Wiirzler, Fahad S. Aldawsari, Rodrigo Aguayo-Ortiz, Arno G. Siraki, Carlos A. Velázquez-Martínez, José L. Medina-Franco, Rafael Pazinatto Aguiar, Naif Aljuhani, Roberto Kenji Nakamura Cuman
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:1411-1415
Resveratrol is a natural compound with a plethora of activities as well as limitations. We recently reported a series of resveratrol-salicylate analogs with potential chemopreventive activity. Herein, we report the anti-inflammatory and antioxidant p
Autor:
Humberto Milani, Lígia Mendes Soares, Erika Meyer, Rafael Pazinatto Aguiar, Adrian Newman-Tancredi, Rúbia Maria Weffort de Oliveira, Mark A. Varney, Jos Prickaerts, Fernanda Canova da Silveira
Publikováno v:
Progress in Neuro-Psychopharmacology & Biological Psychiatry, 99:109832. Elsevier Science
Pharmacological interventions that selectively activate serotonin 5-hydroxytryptramine-1A (5-HT1A) heteroreceptors may prevent or attenuate the consequences of brain ischemic episodes. The present study investigated whether the preferential 5-HT1A po
Autor:
Saulo Euclides Silva-Filho, Francielli Maria de Souza Silva-Comar, Rafael Pazinatto Aguiar, Gabriel Fernando Esteves Cardia, Heitor Augusto Otaviano Cavalcante, Luiz Alexandre Marques Wiirzler, Roberto Kenji Nakamura Cuman, Ciomar Aparecida Bersani-Amado, Nancy Sayuri Uchida, Expedito Leite Silva, Tânia Cristina Alexandrino Becker
Publikováno v:
The American journal of Chinese medicine. 45(3)
To investigate the hepatoprotective effect of Cymbopogon citratus or lemongrass essential oil (LGO), it was used in an animal model of acute liver injury induced by acetaminophen (APAP). Swiss mice were pretreated with LGO (125, 250 and 500[Formula:
Autor:
Ricardo Alexandre Spironello, Saulo Euclides Silva-Filho, Rafael Pazinatto Aguiar, Roberto Kenji Nakamura Cuman, Ciomar Aparecida Bersani-Amado, Eurica M. Nogami, Francielli Maria de Souza Silva-Comar, Rilson Jose do Pinho
Publikováno v:
British Journal of Pharmaceutical Research. 4:2126-2135
Aims: Liver diseases have become one of the major causes of morbidity and mortality all over the world. This study investigated the hepatoprotective and antioxidant effect of rosemary essential oil (REO) and ginger essential oil (GEO), against parace