Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Rafael P. Morganti"'
Autor:
Camila B Mendes-Silverio, Luiz O S Leiria, Rafael P Morganti, Gabriel F Anhê, Sisi Marcondes, Fabíola Z Mónica, Gilberto De Nucci, Edson Antunes
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e47223 (2012)
Background and aimsNitric oxide-independent soluble guanylyl cyclase (sGC) activators reactivate the haem-oxidized enzyme in vascular diseases. This study was undertaken to investigate the anti-platelet mechanisms of the haem-independent sGC activato
Externí odkaz:
https://doaj.org/article/518b0629fd4b4823871dcd9188f75a26
Publikováno v:
European Journal of Pharmacology. 645:158-164
The soluble guanylyl cyclase is expressed in airway smooth muscle, and agents that stimulate this enzyme activity cause airway smooth muscle relaxation and bronchodilation. The compound 5-Cyclopropyl-2-[1-(2-fluoro-benzyl)-1H-pyrazolo[3,4-b]pyridin-3
Autor:
Gilberto De Nucci, Sergio Lilla, Sisi Marcondes, Ferid Murad, Edson Antunes, Marcia H. M. Cardoso, Rafael P. Morganti
Publikováno v:
European Journal of Pharmacology. 627:229-234
Reactive oxygen species have an important role in the control of platelet activity. Superoxide anion (O(2)(-)) is a free radical that can be converted into other reactive oxygen species such as peroxynitrite (ONOO(-)) that is formed from the reaction
Autor:
Sisi Marcondes, Irene Lorand-Metze, Gilberto De Nucci, Edson Antunes, Marcia H. M. Cardoso, Fernanda G. Pereira, Rafael P. Morganti
Publikováno v:
Platelets. 21:260-269
Alterations in platelet aggregation in septic conditions are well established. However, little is known about the effects of lipopolysaccharide (LPS) on platelet adhesion. We have therefore investigated the effects of LPS in human platelet adhesion,
Autor:
Edson Antunes, Rafael P. Morganti, Cleber E. Teixeira, Haroldo A. Toque, Fernanda B.M. Priviero, G. De Nucci
Publikováno v:
British Journal of Pharmacology. 154:787-796
Background and purpose: Phosphodiesterase type-5 (PDE5) inhibitors constitute a novel and important therapeutic option for the treatment of pulmonary hypertension. The effects of the PDE5 inhibitors sildenafil, tadalafil and vardenafil on rabbit isol
Autor:
Paulo A. Baldasso, Gilberto De Nucci, Rafael P. Morganti, Edson Antunes, Sergio Marangoni, Sisi Marcondes
Publikováno v:
Platelets. 19:432-439
Septic shock was formerly recognized as a consequence of Gram-negative bacteraemia, but at present the incidence of Gram-positive sepsis seems to be more relevant, contributing for more than 50% of cases. Staphylococcal aureus can induce toxic shock
Autor:
Helena Serra Azul Monteiro, A. M. C. Martins, Sergio Marangoni, Fabiana Vieira Fonseca, Rafael P. Morganti, Marcos H. Toyama, Edson Antunes, Daniela de Oliveira Toyama
Publikováno v:
The Protein Journal. 25:183-192
In this article we investigated the platelet aggregating activity of whole crotoxin and its subunits isolated from Crotalus durissus cascavella venom. During the purification protocols of the venom, using HPLC molecular exclusion, we detected the pre
Autor:
Maria Elisa Lopes-Pires, Edson Antunes, Sisi Marcondes, Rafael P. Morganti, André Luis Casarin
Publikováno v:
Life sciences. 89(21-22)
Aims Excessive production of nitric oxide (NO) and reactive oxygen species (ROS) in sepsis modulates different cell functions. Since the sepsis severity is associated with the degree of platelet activation, we decided to investigate the role of syste
Autor:
Priscila F. Monteiro, Gláucia C. Mello, Lineu Baldissera-Jr, Edson Antunes, Rafael P. Morganti
Publikováno v:
Pulmonary pharmacologytherapeutics. 23(4)
There is considerable evidence that platelet activation occurs in allergic airways diseases. In this study we aimed to investigate platelet adhesion to immobilized fibrinogen and intracellular calcium levels in a rat model of allergic inflammation. M
Autor:
Ricardo Aparicio, Alexandre Holanda Sampaio, Kyria S. Nascimento, Daniela de Oliveira Toyama, Enilton A. Camargo, Edson Antunes, Fabiana Vieira Fonseca, Simone C.B. Oliveira, Rafael P. Morganti, Benildo Sousa Cavada, Marcos H. Toyama, Celso Shiniti Nagano, Luís Otávio Saggion Beriam, Eudismar Vale Nunes
Publikováno v:
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
BMC Biochemistry, Vol 9, Iss 1, p 16 (2008)
BMC Biochemistry
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
BMC Biochemistry, Vol 9, Iss 1, p 16 (2008)
BMC Biochemistry
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Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51d35044c73f42e042a35490c48757f6