Výsledky vyhledávání - "Rafael Nepomuceno"

Akademický článek

Evidence Linking PPARG Genetic Variants with Periodontitis and Type 2 Diabetes Mellitus in a Brazilian Population

Autor: Thamiris Cirelli, Ingra G. Nicchio, Diego G. Bussaneli, Bárbara R. Silva, Rafael Nepomuceno, Silvana R. P. Orrico, Joni A. Cirelli, Letícia H. Theodoro, Silvana P. Barros, Raquel M. Scarel-Caminaga

Publikováno v: International Journal of Molecular Sciences, Vol 24, Iss 7, p 6760 (2023)

The peroxisome proliferator-activated receptor gamma (PPARG) gene encodes a transcription factor involved in the regulation of complex metabolic and inflammatory diseases. We investigated whether single nucleotide polymorphisms (SNPs) and haplotypes

Externí odkaz: https://doaj.org/article/932f8067a8dd4a9b989ae24bf4732041

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Akademický článek

Polymorphisms in Genes of Lipid Metabolism Are Associated with Type 2 Diabetes Mellitus and Periodontitis, as Comorbidities, and with the Subjects’ Periodontal, Glycemic, and Lipid Profiles

Autor: Ingra G. Nicchio, Thamiris Cirelli, Rafael Nepomuceno, Marco A. R. Hidalgo, Carlos Rossa, Joni A. Cirelli, Silvana R. P. Orrico, Silvana P. Barros, Letícia H. Theodoro, Raquel M. Scarel-Caminaga

Publikováno v: Journal of Diabetes Research, Vol 2021 (2021)

Background. Type 2 diabetes mellitus (T2DM) and periodontitis (P) commonly occur as comorbidities, but the commonalities in the genetic makeup of affected individuals is largely unknown. Since dyslipidemia is a frequent condition in these individuals

Externí odkaz: https://doaj.org/article/b4a6fc968bc64dd3ab8be41afed9a66c

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Akademický článek

Expression Profile of Genes Potentially Associated with Adequate Glycemic Control in Patients with Type 2 Diabetes Mellitus

Autor: Sâmia Cruz Tfaile Corbi, Alliny Souza Bastos, Rafael Nepomuceno, Thamiris Cirelli, Raquel Alves dos Santos, Catarina Satie Takahashi, Cristiane S. Rocha, Silvana Regina Perez Orrico, Claudia V. Maurer-Morelli, Raquel Mantuaneli Scarel-Caminaga

Publikováno v: Journal of Diabetes Research, Vol 2017 (2017)

Despite increasing research in type 2 diabetes mellitus (T2D), there are few studies showing the impact of the poor glycemic control on biological processes occurring in T2D. In order to identify potential genes related to poorly/well-controlled pati

Externí odkaz: https://doaj.org/article/196c20bd76ba40bf8a38aa0ba8fd4128

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Akademický článek

Dyslipidemia rather than Type 2 Diabetes Mellitus or Chronic Periodontitis Affects the Systemic Expression of Pro- and Anti-Inflammatory Genes

Autor: Rafael Nepomuceno, Bárbara Scoralick Villela, Sâmia Cruz Tfaile Corbi, Alliny De Souza Bastos, Raquel Alves Dos Santos, Catarina Satie Takahashi, Silvana Regina Perez Orrico, Raquel Mantuaneli Scarel-Caminaga

Publikováno v: Mediators of Inflammation, Vol 2017 (2017)

A high percentage of type 2 diabetes mellitus (T2D) patients are also affected by dyslipidemia and chronic periodontitis (CP), but no studies have determined the gene expression in patients that are simultaneously affected by all three diseases. We i

Externí odkaz: https://doaj.org/article/fbf88dc2283043d79c63987c742ce045

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Genetic polymorphisms in theInterleukins IL1B, IL4,andIL6are associated with concomitant periodontitis and type 2 diabetes mellitus in Brazilian patients

Autor: Silvana Regina Perez Orrico, Ana Cláudia S. Rios, Silvana P. Barros, Rafael Nepomuceno, Joni Augusto Cirelli, Letícia Helena Theodoro, Thamiris Cirelli, Raquel M. Scarel-Caminaga

Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Made available in DSpace on 2020-12-12T02:14:24Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01 Objective: To assess whether single nucleotide polymorphisms (SNPs) in the IL10, IL1A, IL1B, IL4, TNFA, IL6, OPG, RANK, and RANKL genes, “c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12ef946b8258f2b925e92631fd7d5592
https://doi.org/10.1111/jre.12784

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Polymorphisms and haplotypes in the Interleukin 17 Alfa gene: potential effect of smoking habits in the association with periodontitis and type 2 diabetes mellitus

Autor: Silvana P. Barros, Rafael Nepomuceno, Silvana Regina Perez Orrico, Thamiris Cirelli, Marco Antonio Rimachi Hidalgo, Letícia Helena Theodoro, Ingra Gagno Nicchio, Bárbara Roque da Silva, Joni Augusto Cirelli, Raquel M. Scarel-Caminaga

Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Made available in DSpace on 2021-06-25T10:52:08Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-02-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Few

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60ff84eba35242c3dcd65f4532c4f3d7

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Association of type 2 diabetes mellitus and periodontal disease susceptibility with genome-wide association–identified risk variants in a Southeastern Brazilian population

Autor: Silvana Regina Perez Orrico, Letícia Helena Theodoro, Thamiris Cirelli, Joni Augusto Cirelli, Silvana P. Barros, Rafael Nepomuceno, Raquel M. Scarel-Caminaga, Jéssica Marina Goveia

Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Made available in DSpace on 2021-06-25T10:48:21Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01 Objective: Genome-wide association studies (GWAS) and literature have identified polymorphisms in the KCNJ11, HNF1A, IRS1, TCF7L2, CDKAL1, CD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4911f384b16742644f1199c74dc0f06

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Validation in a Brazilian population of gene markers of periodontitis previously investigated by GWAS and bioinformatic studies

Autor: Kari E. North, Silvana Regina Perez Orrico, Thamiris Cirelli, Carlos Rossa, Mariaelisa Graff, Raquel M. Scarel-Caminaga, Silvana P. Barros, Rafael Nepomuceno, Joni Augusto Cirelli

Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Made available in DSpace on 2021-06-25T10:34:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-05-01 Background: Bioinformatic tools and genome-wide association studies (GWAS) have led to comprehensive identification of single nucleotide poly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e180dcc7fa4f75ed434f4db924b1a76
https://pubmed.ncbi.nlm.nih.gov/32909266

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Functional haplotype in the Interleukin8 (CXCL8) gene is associated with type 2 Diabetes Mellitus and Periodontitis in Brazilian population

Autor: Joni Augusto Cirelli, Silvana P. Barros, Rafael Nepomuceno, Silvana Regina Perez Orrico, Thamiris Cirelli, Bárbara Roque da Silva, Letícia Helena Theodoro, Raquel M. Scarel-Caminaga

Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Made available in DSpace on 2020-12-12T02:21:28Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-11-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Back

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d79285972de04cec0fd7afa1eee934c4
https://pubmed.ncbi.nlm.nih.gov/32905938

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Polymorphisms and haplotypes in the Interleukin 17 Alfa gene: potential effect of smoking habits in the association with periodontitis and type 2 diabetes mellitus

Autor: Marco A, Rimachi Hidalgo, Thamiris, Cirelli, Bárbara Roque, da Silva, Ingra Gagno, Nicchio, Rafael, Nepomuceno, Silvana R P, Orrico, Joni A, Cirelli, Letícia Helena, Theodoro, Silvana P, Barros, Raquel M, Scarel-Caminaga

Publikováno v: Molecular biology reports. 48(2)

Few studies evaluate interrelationships between periodontitis (P) and Type 2 Diabetes Mellitus (T2DM). The aim of this study is to investigate the genetic susceptibility to periodontitis alone, or concomitant with T2DM (as comorbidities), analyzing s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::711032d417d63991b1b576ea6530f51b
https://pubmed.ncbi.nlm.nih.gov/33559820

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