Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Rafael Melani"'
Autor:
Luis F. Schachner, Christopher Mullen, Wilson Phung, Joshua D. Hinkle, Michelle Irwin Beardsley, Tracy Bentley, Peter Day, Christina Tsai, Siddharth Sukumaran, Tomasz Baginski, Danielle DiCara, Nicholas J. Agard, Matthieu Masureel, Joshua Gober, Adel M. ElSohly, Rafael Melani, John E. P. Syka, Romain Huguet, Michael T. Marty, Wendy Sandoval
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The heterogeneity inherent in today’s biotherapeutics, especially as a result of heavy glycosylation, can affect a molecule’s safety and efficacy. Characterizing this heterogeneity is crucial for drug development and quality assessment,
Externí odkaz:
https://doaj.org/article/1f51a60ae7254824a781e70ff1592428
This standard protocol details how to make a standard mix of proteins for tracking LC-MS performance and illustrates how to configure an instrument for high-quality data collection. This protocol was developed with support from the National Institute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::113942ec7d1256eaad7ff8b2a5e19d43
https://doi.org/10.17504/protocols.io.bt27nqhn
https://doi.org/10.17504/protocols.io.bt27nqhn
Describes the CZE-MS/MS data acquisition procedure for top-down proteomics samples using the Thermo Scientific Orbitrap Eclipse Tribrid mass spectrometer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eecd719359ba94ac05ba2c660efaec7b
https://doi.org/10.17504/protocols.io.btxdnpi6
https://doi.org/10.17504/protocols.io.btxdnpi6
Describes the LC-MS/MS data acquisition procedure for top-down proteomics samples using the Thermo Scientific Orbitrap Eclipse Tribrid mass spectrometer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af7ed9649988003c0fad27279e8c7d0c
https://doi.org/10.17504/protocols.io.bttknnkw
https://doi.org/10.17504/protocols.io.bttknnkw
Describes the LC-MS/MS data acquisition procedure for top-down proteomics samples.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a4761c0d3437941d99e68cecd7e3089
https://doi.org/10.17504/protocols.io.bnh9mb96
https://doi.org/10.17504/protocols.io.bnh9mb96