Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Rafael M. Rezende"'
Autor:
Hadi Abou-El-Hassan, Rafael M. Rezende, Saef Izzy, Galina Gabriely, Taha Yahya, Bruna K. Tatematsu, Karl J. Habashy, Juliana R. Lopes, Gislane L. V. de Oliveira, Amir-Hadi Maghzi, Zhuoran Yin, Laura M. Cox, Rajesh Krishnan, Oleg Butovsky, Howard L. Weiner
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Traumatic brain injury (TBI) is a leading cause of morbidity and mortality. The innate and adaptive immune responses play an important role in the pathogenesis of TBI. Gamma-delta (γδ) T cells have been shown to affect brain immunopatholog
Externí odkaz:
https://doaj.org/article/6a5a1b424fcc41eabd0e3bb1b781dd2c
Autor:
Hadi Abou-El-Hassan, Joshua D. Bernstock, Joshua I. Chalif, Taha Yahya, Rafael M. Rezende, Howard L. Weiner, Saef Izzy
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
The neuroimmunology of traumatic brain injury (TBI) has recently gained recognition as a crucial element in the secondary pathophysiological consequences that occur following neurotrauma. Both immune cells residing within the central nervous system (
Externí odkaz:
https://doaj.org/article/2ea49716601344ab965324de08bf8528
Autor:
Rafael M. Rezende, Laura M. Cox, Thais G. Moreira, Shirong Liu, Selma Boulenouar, Fyonn Dhang, Danielle S. LeServe, Brenda N. Nakagaki, Juliana R. Lopes, Bruna K. Tatematsu, Luisa Lemos, Julia Mayrink, Eduardo L. C. Lobo, Lydia Guo, Marilia G. Oliveira, Chantal Kuhn, Howard L. Weiner
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-21 (2023)
Abstract Background Gamma-delta (γδ) T cells are a major cell population in the intestinal mucosa and are key mediators of mucosal tolerance and microbiota composition. Little is known about the mechanisms by which intestinal γδ T cells interact
Externí odkaz:
https://doaj.org/article/ebed5f4b59324144aeb29e2ce77e641f
Autor:
Thais G. Moreira, Davide Mangani, Laura M. Cox, Jeffrey Leibowitz, Eduardo. L. C. Lobo, Mariana A. Oliveira, Christian D. Gauthier, Brenda N. Nakagaki, Valerie Willocq, Anya Song, Lydia Guo, David C. A. Lima, Gopal Murugaiyan, Oleg Butovsky, Galina Gabriely, Ana C. Anderson, Rafael M. Rezende, Ana Maria C. Faria, Howard L. Weiner
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Dendritic cells initiate and regulate adaptive immunity and differ according to gut anatomical location. Here the authors show that DC residing in the upper and lower intestines show differential PD-L1 and XCR1 expression and drive specific T cell re
Externí odkaz:
https://doaj.org/article/f3a9efe8e82843f4aa28ca11b29546aa
Autor:
Luciana P. Tavares, Thayse R. Brüggemann, Rafael M. Rezende, Marina G. Machado, R. Elaine Cagnina, Ashley E. Shay, Cristiana C. Garcia, Julie Nijmeh, Mauro M. Teixeira, Bruce D. Levy
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT Influenza A virus (IAV) infections are a leading cause of mortality worldwide. Excess mortality during IAV epidemics and pandemics is attributable to secondary bacterial infections, particularly pneumonia caused by Streptococcus pneumoniae.
Externí odkaz:
https://doaj.org/article/3a864d6cb7fe4807bf4973222976c38d
Autor:
Thais G. Moreira, Kimble T. F. Matos, Giovana S. De Paula, Thais M. M. Santana, Raquel G. Da Mata, Fernando C. Pansera, Andre S. Cortina, Marcelle G. Spinola, Clare M. Baecher-Allan, Gerson D. Keppeke, Jules Jacob, Vaseem Palejwala, Karen Chen, Saef Izzy, Brian C. Healey, Rafael M. Rezende, Rogerio A. Dedivitis, Kunwar Shailubhai, Howard L. Weiner
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/ad921884fc424e0688f770608f9a93f2
Autor:
Galina Gabriely, Duanduan Ma, Shafiuddin Siddiqui, Linqing Sun, Nathaniel P. Skillin, Hadi Abou-El-Hassan, Thais G. Moreira, Dustin Donnelly, Andre P. da Cunha, Mai Fujiwara, Lena R. Walton, Amee Patel, Rajesh Krishnan, Stuart S. Levine, Brian C. Healy, Rafael M. Rezende, Gopal Murugaiyan, Howard L. Weiner
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103347- (2021)
Summary: Myeloid suppressor cells promote tumor growth by a variety of mechanisms which are not fully characterized. We identified myeloid cells (MCs) expressing the latency-associated peptide (LAP) of TGF-β on their surface and LAPHi MCs that stimu
Externí odkaz:
https://doaj.org/article/cd2b4250e05d4e979dda9bd8430b32ec
Autor:
Thais G. Moreira, Kimble T. F. Matos, Giovana S. De Paula, Thais M. M. Santana, Raquel G. Da Mata, Fernando C. Pansera, Andre S. Cortina, Marcelle G. Spinola, Clare M. Baecher-Allan, Gerson D. Keppeke, Jules Jacob, Vaseem Palejwala, Karen Chen, Saef Izzy, Brian C. Healey, Rafael M. Rezende, Rogerio A. Dedivitis, Kunwar Shailubhai, Howard L. Weiner
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundImmune hyperactivity is an important contributing factor to the morbidity and mortality of COVID-19 infection. Nasal administration of anti-CD3 monoclonal antibody downregulates hyperactive immune responses in animal models of autoimmunity
Externí odkaz:
https://doaj.org/article/b1a9e151506d41928c312969f7c3db27
Autor:
Rafael M. Rezende, Amanda J. Lanser, Stephen Rubino, Chantal Kuhn, Nathaniel Skillin, Thais G. Moreira, Shirong Liu, Galina Gabriely, Bruna A. David, Gustavo B. Menezes, Howard L. Weiner
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Many immune functions have been reported for γδ T cells, including the regulation of antibody responses. Here the authors show that CXCR5+ γδ T cells release Wnt ligands to initiate the T follicular helper cell differentiation program and promote
Externí odkaz:
https://doaj.org/article/5adbc105176d41f49ebebc1453323bb6
Autor:
BRENDA N. NAKAGAKI, MARIA A. FREITAS-LOPES, ÉRIKA CARVALHO, RAQUEL CARVALHO-GONTIJO, HORTÊNCIA M. CASTRO-OLIVEIRA, RAFAEL M. REZENDE, DENISE C. CARA, MÔNICA M. SANTOS, RODRIGO PESTANA LOPES, BRUNA A. DAVID, GUSTAVO B. MENEZES
Publikováno v:
Anais da Academia Brasileira de Ciências, Iss 0 (2017)
ABSTRACT Resident and circulating immune cells have been extensively studied due to their almost ubiquitous role in cell biology. Despite their classification under the “immune cell department”, it is becoming increasingly clear that these cells
Externí odkaz:
https://doaj.org/article/72399394402d4373ae12a21f05a38e5e