Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Rafael Leite Morais"'
Autor:
Gabriel R. Estrela, Frederick Wasinski, Marcos F. Gregnani, Leandro C. Freitas-Lima, Adriano C. Arruda, Rafael Leite Morais, Denise MAC Malheiros, Niels O. S. Camara, João Bosco Pesquero, Michael Bader, Carlos Castilho Barros, Ronaldo Carvalho Araújo
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Cisplatin is a highly effective chemotherapeutic agent. However, its use is limited by nephrotoxicity. Enalapril is an angiotensin I-converting enzyme inhibitor used for the treatment of hypertension, mainly through the reduction of angiotensin II fo
Externí odkaz:
https://doaj.org/article/02b001a1ddfe41de95c51396dd191ae7
Autor:
Cynthia Silva, Bartolomeo, Robertha Mariana Rodrigues, Lemes, Rafael Leite, Morais, Gabriela Cruz, Pereria, Tamires Alves, Nunes, Angelica Jardim, Costa, Rui Monteiro, de Barros Maciel, Carla Torres, Braconi, Juliana Terzi, Maricato, Luiz Mario Ramos, Janini, Liria Hiromi, Okuda, Kil Sun, Lee, Carla Máximo, Prado, Rodrigo Portes, Ureshino, Roberta Sessa, Stilhano
Publikováno v:
Life Sciences. 308:120930
This study evaluated SARS-CoV-2 replication in human cell lines derived from various tissues and investigated molecular mechanisms related to viral infection susceptibility and replication.SARS-CoV-2 replication in BEAS-2B and A549 (respiratory tract
Autor:
João Bosco Pesquero, Clovis R. Nakaie, Rafael Leite Morais, Michael Bader, Jair R. Chagas, Natalia Alenina, Marcelo A. Mori, Adriana K. Carmona, Aline M Hilzendeger, Mihail Todiras, Bruna Visniauskas, Ronaldo C. Araujo
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 312:H437-H445
Obesity is assumed to be a major cause of human essential hypertension; however, the mechanisms responsible for weight-related increase in blood pressure (BP) are not fully understood. The prevalence of hypertension induced by obesity has grown over
Autor:
Vinicius Duval da Silva, Natália Fontana Nicoletti, Nelson Pires Ferreira, Maria M. Campos, Jacques Sénécal, Réjean Couture, Fernanda Bueno Morrone, Marcelo Ricardo Roxo, João Bosco Pesquero, Rafael Leite Morais
Publikováno v:
Molecular Neurobiology. 54:7869-7882
This study investigated the role of kinins and their receptors in malignant brain tumors. As a first approach, GL-261 glioma cells were injected (2 × 105 cells in 2 μl/2 min) into the right striatum of adult C57/BL6 wild-type, kinin B1 and B2 recep
Autor:
Suma I. Shimuta, Rosana I. Reis, Clovis R. Nakaie, Dulce Elena Casarini, Rafael Leite Morais, Paola Bianchi Guimarães, Erika Costa de Alvarenga, Alice T. Ferreira, Edgar J. Paredes-Gamero, Michael Bader, João Bosco Pesquero, Regiane A. Sabatini, Renan Paulo Martin, Jorge L. Pesquero, Adriana K. Carmona, Edson Lucas dos Santos, Miriam Galvonas Jasiulionis, Suzana M. Oliveira, Claudio M. Costa-Neto, Paula D. Siqueira, Luis Gustavo de Deus Teixeira
Publikováno v:
Hypertension. 57:965-972
Angiotensin (Ang) I–converting enzyme (ACE) is involved in the control of blood pressure by catalyzing the conversion of Ang I into the vasoconstrictor Ang II and degrading the vasodilator peptide bradykinin. Human ACE also functions as a signal tr
Autor:
Volkmar Gross, Ronaldo C. Araujo, Mihail Todiras, Michael Bader, Adriana K. Carmona, Andrey Ch. da Costa Goncalves, Fatimunnisa Qadri, Clovis R. Nakaie, Aline M Hilzendeger, João Bosco Pesquero, Dulce Elena Casarini, Rafael Leite Morais, Ralph Plehm
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 88(9)
Leptin is a hormone related to metabolism. It also influences blood pressure, but the mechanisms triggered in this process are not yet elucidated. Angiotensin-I converting enzyme (ACE) regulates cardiovascular functions and recently has been associat
Autor:
Vicencia Sales, Rafael Leite Morais, Rafael Filippelli-Silva, João Bosco Pesquero, Elton Dias da Silva, Marcelo A. Mori, Michael Bader
Publikováno v:
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
Rafael L Morais,1 Elton D Silva,1 Vicência M Sales,1 Rafael Filippelli-Silva,1 Marcelo A Mori,1 Michael Bader,2 João B Pesquero1 1Department of Biophysics, Universidade Federal de São Paulo, São Paulo, Brazil; 2Max-Delbrück Center for Molecular