Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Rafael Leite Dantas"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background Restoring impaired peripheral immune tolerance is the primary challenge in treating autoimmune diseases. Our previous research demonstrated the effectiveness of small spleen peptides (SSPs), a fraction of low molecular weight prot
Externí odkaz:
https://doaj.org/article/ac3f29972f4c485e93914cd061931059
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 469 (2024)
Restoring peripheral immune tolerance is crucial for addressing autoimmune diseases. An ancient mechanism in maintaining the balance between inflammation and tolerance is the ratio of extracellular ATP (exATP) and adenosine. Our previous research dem
Externí odkaz:
https://doaj.org/article/d85ba9c30ede4d819acc0fbc3ca87f5a
Autor:
Jana Freff, Lisa Bröker, Rafael Leite Dantas, Kathrin Schwarte, Judith Bühlmeier, Isabelle Kraft, Anke Hinney, Ulrike Buhlmann, Volker Arolt, Udo Dannlowski, Georg Romer, Bernhard T. Baune, Johannes Hebebrand, Manuel Föcker, Judith Alferink
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Anorexia nervosa (AN) is a severe eating disorder characterized by excessive weight loss and lack of recognition of the seriousness of the current low body weight. Individuals with AN frequently exhibit an enhanced inflammatory state and altered bloo
Externí odkaz:
https://doaj.org/article/05ff4e4197cd49989916aa982b7bb3eb
Publikováno v:
Molecular Therapy: Oncolytics, Vol 17, Iss , Pp 190-204 (2020)
Recently, we showed that infection of primary lung tumor-bearing mice with oncolytic influenza A viruses (IAVs) led to strong virus-induced tumor cell lysis but also to restoration of immune competence of innate immune cells. Murine B16-F10 melanoma
Externí odkaz:
https://doaj.org/article/d458c465ae544720b1c71af883fcb757
Autor:
Rafael Leite Dantas, Jana Freff, Oliver Ambrée, Eva C. Beins, Andreas J. Forstner, Udo Dannlowski, Bernhard T. Baune, Stefanie Scheu, Judith Alferink
Publikováno v:
Cells, Vol 10, Iss 4, p 941 (2021)
Affective disorders (AD) including major depressive disorder (MDD) and bipolar disorder (BD) are common mood disorders associated with increased disability and poor health outcomes. Altered immune responses characterized by increased serum levels of
Externí odkaz:
https://doaj.org/article/40351825b9c341c38eb4ff1acff058e0
Autor:
Evelyn Gaffal, Andrea M. Kemter, Stefanie Scheu, Rafael Leite Dantas, Jens Vogt, Bernhard Baune, Thomas Tüting, Andreas Zimmer, Judith Alferink
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 2, p 475 (2020)
Contact hypersensitivity (CHS) is an established animal model for allergic contact dermatitis. Dendritic cells (DCs) play an important role in the sensitization phase of CHS by initiating T cell responses to topically applied haptens. The cannabinoid
Externí odkaz:
https://doaj.org/article/3587b93e7ffe49518d7fe3f17d8a0de6
Autor:
Tanja Schied, Dörthe Masemann, Viktor Wixler, Yvonne Boergeling, Veronika Lührmann, Igor Z. Zaytsev, Stephan Ludwig, Georg Varga, Rafael Leite Dantas
Publikováno v:
Mol Ther
The major challenge in the treatment of autoimmune diseases is the restoration of the impaired peripheral immune tolerance that always accompanies the development of such diseases. Here, we show that small splenic peptides (SSPs) of whole spleen extr
Autor:
Jana Freff, Eva C. Beins, Lisa Bröker, Kathrin Schwarte, Rafael Leite Dantas, Carlo Maj, Volker Arolt, Udo Dannlowski, Markus M. Nöthen, Bernhard T. Baune, Andreas J. Forstner, Judith Alferink
Publikováno v:
Journal of affective disorders. 310
Chemokines and their receptors regulate inflammatory processes in major depressive disorder (MDD). Here, we characterize the expression pattern of the C-C chemokine receptor 4 (CCR4) and its ligands CCL17 and CCL22 in MDD and its clinical relevance i
Autor:
Johannes Roth, Ulrich Dobrindt, Rafael Leite Dantas, Viktor Wixler, Georg Varga, Haleluya Wami, Stephan Ludwig, Thomas J. Vogl, Dominik Bettenworth, Toni Weinhage
Publikováno v:
The Journal of Pathology. 251:388-399
Recently, we established a doxycycline-inducible human tumor necrosis factor alpha (TNFα)-transgenic mouse line, ihTNFtg. Non-induced young and elderly mice showed low but constitutive expression of hTNFα due to promoter leakiness. The persistently
Autor:
Stefanie Scheu, Evelyn Gaffal, Bernhard T. Baune, Andrea M. Kemter, Judith Alferink, Jens Vogt, Andreas Zimmer, Thomas Tüting, Rafael Leite Dantas
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 2
International Journal of Molecular Sciences, Vol 21, Iss 2, p 475 (2020)
Volume 21
Issue 2
International Journal of Molecular Sciences, Vol 21, Iss 2, p 475 (2020)
Contact hypersensitivity (CHS) is an established animal model for allergic contact dermatitis. Dendritic cells (DCs) play an important role in the sensitization phase of CHS by initiating T cell responses to topically applied haptens. The cannabinoid