Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Rafael Lazo Gómez"'
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 10 (2023)
Externí odkaz:
https://doaj.org/article/6e9687f0e02e432694bf829bfb8d3625
Autor:
José Manuel Albisua Aguilar, Francisco Ortega Vallado, Orlando Carrillo Torres, Rafael Lazo Gómez, María Elena Pinto Segura
Publikováno v:
Acta Médica Grupo Ángeles. 21:134-139
Autor:
Rafael Lazo-Gómez, Ricardo Tapia
Publikováno v:
Translational Neurodegeneration
Translational Neurodegeneration, Vol 6, Iss 1, Pp 1-14 (2017)
Translational Neurodegeneration, Vol 6, Iss 1, Pp 1-14 (2017)
Background Excitotoxicity is a mechanism of foremost importance in the selective motor neuron degeneration characteristic of motor neuron disorders. Effective therapeutic strategies are an unmet need for these disorders. Polyphenols, such as querceti
Publikováno v:
Neuropharmacology. 82:101-107
In the spinal cord neuronal activity is controlled by the balance between excitatory and inhibitory neurotransmission, mediated mainly by the neurotransmitters glutamate and GABA/glycine, respectively. Alterations of this equilibrium have been associ
Autor:
Rafael Lazo-Gómez, Ricardo Tapia
Publikováno v:
Frontiers in Neuroscience, Vol 10 (2016)
Frontiers in Neuroscience
Frontiers in Neuroscience
Motor neuron degeneration is the pathological hallmark of motor neuron diseases, a group of neurodegenerative disorders clinically manifested as muscle fasciculations and hyperreflexia, followed by paralysis, respiratory failure and death. Ample evid
Publikováno v:
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 8 (2014)
Frontiers in Cellular Neuroscience, Vol 8 (2014)
Motor neuron physiology and development depend on a continuous and tightly regulated trophic support from a variety of cellular sources. Trophic factors guide the generation and positioning of motor neurons during every stage of the developmental pro
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 7 (2013)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, characterized by the progressive loss of motor neurons. The cause of this selective neuronal death is unknown, but transcriptional dysregulation is recently emerging as an impo