Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Rafael L. Rovina"'
1
Akademický článek
IL-6 deletion decreased REV-ERBα protein and influenced autophagy and mitochondrial markers in the skeletal muscle after acute exercise
Autor: Ana P. Pinto, Vitor R. Muñoz, Alisson L. da Rocha, Rafael L. Rovina, Gustavo D. Ferrari, Luciane C. Alberici, Fernando M. Simabuco, Giovana R. Teixeira, José R. Pauli, Leandro P. de Moura, Dennys E. Cintra, Eduardo R. Ropelle, Ellen C. Freitas, Donato A. Rivas, Adelino S. R. da Silva
Publikováno v: Frontiers in Immunology, Vol 13 (2022)
Interleukin 6 (IL-6) acts as a pro and anti-inflammatory cytokine, has an intense correlation with exercise intensity, and activates various pathways such as autophagy and mitochondrial unfolded protein response. Also, IL-6 is interconnected to circa
Externí odkaz: https://doaj.org/article/c7e31ad4f3744cd9b15f46520e235d68
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2
Akademický článek
One Bout of Aerobic Exercise Can Enhance the Expression of Nr1d1 in Oxidative Skeletal Muscle Samples
Autor: Rafael L. Rovina, Alisson L. da Rocha, Bruno B. Marafon, José R. Pauli, Leandro P. de Moura, Dennys E. Cintra, Eduardo R. Ropelle, Adelino S. R. da Silva
Publikováno v: Frontiers in Physiology, Vol 12 (2021)
The nuclear receptor subfamily 1, group D member 1 (Nr1d1), plays a role in the skeletal muscle’s oxidative capacity, mitochondrial biogenesis, atrophy genes, and muscle fiber size. In light of the effects of physical exercise, the present study in
Externí odkaz: https://doaj.org/article/2339bd6decdc4da2858ccab9a1b54994
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3
Genetic deletion of IL‐6 increases CK‐MB, a classic cardiac damage marker, and decreases UPRmt genes after exhaustive exercise
Autor: Rafael L. Rovina, Ana P. Pinto, Vitor R. Muñoz, Alisson L. da Rocha, Macario A. Rebelo, Giovana R. Teixeira, Maria Eduarda A. Tavares, José R. Pauli, Leandro P. de Moura, Dennys E. Cintra, Eduardo R. Ropelle, Adelino S. R. da Silva
Publikováno v: Cell Biochemistry and Function. 40:369-378
The intensity, duration, type of contraction, and muscle damage influence interleukin-6 (IL-6) response to acute exercise. However, in response to an exhaustive exercise session, the upregulation of IL-6 in the serum and heart is associated with an i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab2d841ba212ee88c5d1c440f563b209
https://doi.org/10.1002/cbf.3701
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6
Impact of Different Physical Exercises on the Expression of Autophagy Markers in Mice
Autor: Ana P. Pinto, Dennys E. Cintra, Lilian Eslaine Costa Mendes da Silva, Leandro Pereira de Moura, Adelino Sanchez Ramos da Silva, Alisson L. da Rocha, Vitor Rosetto Muñoz, Bruno B. Marafon, Rafael L. Rovina, José Rodrigo Pauli, Eduardo R. Ropelle
Publikováno v: International Journal of Molecular Sciences
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
International Journal of Molecular Sciences, Vol 22, Iss 2635, p 2635 (2021)
Volume 22
Issue 5
Although physical exercise-induced autophagy activation has been considered a therapeutic target to enhance tissue health and extend lifespan, the effects of different exercise models on autophagy in specific metabolic tissues are not completely unde
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83e7a894cf927c685fb9d1c4339837d1
http://europepmc.org/articles/PMC7962017
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7
Role of interleukin-6 in inhibiting hepatic autophagy markers in exercised mice
Autor: Fernando Moreira Simabuco, Eike B. Kohama, Elisa Cabrera, Eduardo R. Ropelle, Leandro Pereira de Moura, Rafael L. Rovina, Carlos Roberto Bueno Júnior, José Rodrigo Pauli, Ana P. Pinto, Bruno B. Marafon, Adelino Sanchez Ramos da Silva, Alisson L. da Rocha, Dennys E. Cintra
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Background Based on the crosstalk of inflammation with apoptosis, autophagy, and endoplasmic reticulum (ER) stress, the main objective of this study was to explore the role of interleukin-6 (IL-6) on genes and proteins related to these phenomena in t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc83934ea60fc4b26347477f60a392de
https://pubmed.ncbi.nlm.nih.gov/32259772
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8
Moderate, but Not Excessive, Training Attenuates Autophagy Machinery in Metabolic Tissues
Autor: Adelino Sanchez Ramos da Silva, Donato A. Rivas, Giovana R. Teixeira, Rafael L. Rovina, José Rodrigo Pauli, Allice Santos Cruz Veras, Ana P. Pinto, Alisson L. da Rocha, Gustavo P. Morais, Leandro Pereira de Moura, Dennys E. Cintra, Bruno B. Marafon, Eduardo R. Ropelle
Publikováno v: International Journal of Molecular Sciences
Volume 21
Issue 22
International Journal of Molecular Sciences, Vol 21, Iss 8416, p 8416 (2020)
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
The protective effects of chronic moderate exercise-mediated autophagy include the prevention and treatment of several diseases and the extension of lifespan. In addition, physical exercise may impair cellular structures, requiring the action of the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd50e4a86cea3005a562e562574687a
https://doi.org/10.3390/ijms21228416
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9
Tlr4 participates in the responses of markers of apoptosis, inflammation, and ER stress to different acute exercise intensities in mice hearts
Autor: Alisson L. da Rocha, Dennys E. Cintra, Fabiani Gai Frantz, Rafael Calais Gaspar, Ana P. Pinto, Lilian Eslaine Costa Mendes da Silva, Eduardo R. Ropelle, Fernando Moreira Simabuco, Adelino Sanchez Ramos da Silva, Larissa G. de Vicente, Vitor Rosetto Muñoz, Rafael L. Rovina, José Rodrigo Pauli, Leandro Pereira de Moura
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Background Toll-like receptor 4 (Tlr4) is recognized due to its role in the immune response. Also, this protein can participate in the signaling pathway of events triggered by physical exercise such as apoptosis, inflammation, and endoplasmic reticul
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d775d845724a51a976021059e91acb
https://doi.org/10.1016/j.lfs.2019.117107
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