Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Rafael L. B. Lino"'
1
Akademický článek
Recombinant RGD-disintegrin DisBa-01 blocks integrin αvβ3 and impairs VEGF signaling in endothelial cells
Autor: Taís M. Danilucci, Patty K. Santos, Bianca C. Pachane, Graziéle F. D. Pisani, Rafael L. B. Lino, Bruna C. Casali, Wanessa F. Altei, Heloisa S. Selistre-de-Araujo
Publikováno v: Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-15 (2019)
Abstract Background Integrins mediate cell adhesion, migration, and survival by connecting the intracellular machinery with the surrounding extracellular matrix. Previous studies demonstrated the interaction between αvβ3 integrin and VEGF type 2 re
Externí odkaz: https://doaj.org/article/7c4939f4fff943f3b277664b981e17e6
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2
Akademický článek
Inhibition of αvβ3 integrin induces loss of cell directionality of oral squamous carcinoma cells (OSCC).
Autor: Cyntia F Montenegro, Bruna C Casali, Rafael L B Lino, Bianca C Pachane, Patty K Santos, Alan R Horwitz, Heloisa S Selistre-de-Araujo, Marcelo L Lamers
Publikováno v: PLoS ONE, Vol 12, Iss 4, p e0176226 (2017)
The connective tissue formed by extracellular matrix (ECM) rich in fibronectin and collagen consists a barrier that cancer cells have to overpass to reach blood vessels and then a metastatic site. Cell adhesion to fibronectin is mediated by αvβ3 an
Externí odkaz: https://doaj.org/article/2fa559d2008546f6b4a18c0853c45711
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3
Alternagin-C (ALT-C), a disintegrin-like protein, attenuates alpha2beta1 integrin and VEGF receptor 2 signaling resulting in angiogenesis inhibition
Autor: Taís M. Danilucci, Rafael L. B. Lino, Ana Carolina Caetano Nunes, Patty Karina dos Santos, Heloisa S. Selistre-de-Araujo, Bianca C. Pachane, Wanessa F. Altei
Publikováno v: Biochimie. 174:144-158
Angiogenesis, a crucial process in tumor progression, is mainly regulated by vascular endothelial growth factor (VEGF) and its receptor, VEGFR2. Studies have shown the interaction between α2β1 integrin, a collagen receptor, and VEGFR2 in VEGF-drive
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c603da23c30867fafcb328fac6d18c
https://doi.org/10.1016/j.biochi.2020.04.023
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4
Recombinant RGD-disintegrin DisBa-01 blocks integrin αvβ3 and impairs VEGF signaling in endothelial cells
Autor: Wanessa F. Altei, Patty Karina dos Santos, Bruna C. Casali, Rafael L. B. Lino, Graziéle Fernanda Deriggi Pisani, Taís M. Danilucci, Bianca C. Pachane, Heloisa S. Selistre-de-Araujo
Publikováno v: Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-15 (2019)
Cell Communication and Signaling : CCS
Background Integrins mediate cell adhesion, migration, and survival by connecting the intracellular machinery with the surrounding extracellular matrix. Previous studies demonstrated the interaction between αvβ3 integrin and VEGF type 2 receptor (V
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d7ede3a40e4523556830bd13c4714d1
http://link.springer.com/article/10.1186/s12964-019-0339-1
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5
Alphavbeta3 integrin blocking inhibits apoptosis and induces autophagy in murine breast tumor cells
Autor: Patty Karina dos Santos, Graziéle Fernanda Deriggi Pisani, Heloisa S. Selistre-de-Araujo, Wanessa F. Altei, Márcia Regina Cominetti, Rafael L. B. Lino
Publikováno v: Biochimica et biophysica acta. Molecular cell research. 1866(12)
Integrins are cell receptors that mediate adhesion to the extracellular matrix (ECM) and regulate cell migration, a crucial process in tumor invasion. The αvβ3 integrin recognizes the arginine-glycine-aspartic acid (RGD) motif in ECM proteins and i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41268f529290e7421a92b357f68e208a
https://pubmed.ncbi.nlm.nih.gov/31465809
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6
Inhibition of αvβ3 integrin induces loss of cell directionality of oral squamous carcinoma cells (OSCC)
Autor: Rafael L. B. Lino, Marcelo Lazzaron Lamers, Alan Rick Horwitz, Heloisa S. Selistre-de-Araujo, Bianca C. Pachane, Bruna C. Casali, Patty Karina dos Santos, Cyntia de Freitas Montenegro
Publikováno v: PLoS ONE
Repositório Institucional da UFRGS
Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
PLoS ONE, Vol 12, Iss 4, p e0176226 (2017)
The connective tissue formed by extracellular matrix (ECM) rich in fibronectin and collagen consists a barrier that cancer cells have to overpass to reach blood vessels and then a metastatic site. Cell adhesion to fibronectin is mediated by αvβ3 an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b28ce9f1c5c6d052a6975c01399ef26d
http://europepmc.org/articles/PMC5402964
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7
Reduced collagen accumulation and augmented MMP-2 activity in left ventricle of old rats submitted to high-intensity resistance training
Autor: André S. Mecawi, Hernandes F. Carvalho, Heloisa S. Selistre-de-Araujo, Vinicius Guzzoni, Jeffrey M. Hord, Jonh M. Lawler, Rita de Cássia Marqueti, José Antunes Rodrigues, Ana Paula Davel, João Luiz Quagliotti Durigan, Tayná Oliveira Costa Santos, Rafael L. B. Lino, Marcelo Shinyu Mekaro
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Progressive fibrosis is a hallmark of the aging heart. Age-related fibrosis is modulated by endurance exercise training; however, little is known concerning the influence of resistance training (RT). Therefore we investigated the chronic effects of h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46f7be85f7ab2c870026f6d920e74ee2
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8
ADAM9 silencing inhibits breast tumor cells transmigration through blood and lymphatic endothelial cells
Autor: Heloisa S. Selistre-de-Araujo, Verônica Morandi, Rafael L. B. Lino, Kelli Cristina Micocci, Milene Nóbrega de Oliveira Moritz, Antonio Gilclêr Ferreira Lima, Laila Ribeiro Fernandes, Camila C. Figueiredo
Publikováno v: Biochimie.
ADAMs are transmembrane multifunctional proteins that contain disintegrin and metalloprotease domains. ADAMs act in a diverse set of biological processes, including fertilization, inflammatory responses, myogenesis, cell migration, cell proliferation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eeb5303db53a1babeaad0006d0b2e7d
https://pubmed.ncbi.nlm.nih.gov/27554339
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9
Abstract A53: [10]-gingerol interferes with the adhesion of MDA-MB-231 tumor cells to extracellular matrix
Autor: Paulo C. Vieira, Heloisa Sobreiro Selistre de Araújo, Ana Carolina Baptista Moreno Martin, Márcia Regina Cominetti, Ronaldo C. Faria, Carolina Venturini Uliana, James Almada da Silva, Amanda Blanque Becceneri, Angelina M. Fuzer, Rafael L. B. Lino, Rodolpho de Campos Braga, Rebeka Tomasin
Publikováno v: Molecular Cancer Research. 16:A53-A53
Breast cancer is one of the most common malignant diseases in women worldwide. In developing countries, it is the second highest cause of death in women. Triple-negative breast cancer (TNBC) represents the approximately 15% of breast cancers that lac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9e40f0d6e19e1677e7a01553c0446196
https://doi.org/10.1158/1557-3125.advbc17-a53
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