Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Rafael López-Blanch"'
Autor:
Sandra Carrera-Juliá, Elena Obrador, Rafael López-Blanch, María Oriol-Caballo, Paz Moreno-Murciano, José M. Estrela
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
A recent pilot study in amyotrophic lateral sclerosis (ALS) patients analyzed the effect of a Mediterranean diet (MeDi) supplemented with nicotinamide riboside (NR, a NAD+ promoter), pterostilbene (PTER, a natural antioxidant) and/or coconut oil on a
Externí odkaz:
https://doaj.org/article/42d8156464c14488a2c5d3b9970a6439
Autor:
Elena Obrador, Rosario Salvador-Palmer, Blanca Pellicer, Rafael López-Blanch, J. Antoni Sirerol, Juan I. Villaescusa, Alegría Montoro, Ryan W. Dellinger, José M. Estrela
Publikováno v:
Journal of Advanced Research, Vol 45, Iss , Pp 73-86 (2023)
Introduction: Effective agents that could confer long-term protection against ionizing radiation in vivo would have applications in medicine, biotechnology, and in air and space travel. However, at present, drugs that can effectively protect against
Externí odkaz:
https://doaj.org/article/1cc6e573e6a544d395ea6fb871e2e429
Autor:
Elena Obrador, Paz Moreno-Murciano, María Oriol-Caballo, Rafael López-Blanch, Begoña Pineda, Julia Lara Gutiérrez-Arroyo, Alba Loras, Luis G. Gonzalez-Bonet, Conrado Martinez-Cadenas, José M. Estrela, María Ángeles Marqués-Torrejón
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2529 (2024)
Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer. Although great efforts have been made by clinicians and researchers, no significant improvement in survival has been achieved since the Stupp protocol became the stan
Externí odkaz:
https://doaj.org/article/3f54dc8d7be147a9a13286a1d54407b9
Autor:
Elena Obrador, Ali Jihad-Jebbar, Rosario Salvador-Palmer, Rafael López-Blanch, María Oriol-Caballo, María Paz Moreno-Murciano, Enrique A. Navarro, Rosa Cibrian, José M. Estrela
Publikováno v:
Cancers, Vol 15, Iss 13, p 3413 (2023)
At present, the applications and efficacy of non-ionizing radiations (NIR) in oncotherapy are limited. In terms of potential combinations, the use of biocompatible magnetic nanoparticles as heat mediators has been extensively investigated. Neverthele
Externí odkaz:
https://doaj.org/article/8d03c44f6d154d459747d19b5d4785b9
Autor:
Elena Obrador, Rosario Salvador-Palmer, Rafael López-Blanch, María Oriol-Caballo, Paz Moreno-Murciano, José M. Estrela
Publikováno v:
Cells, Vol 12, Iss 3, p 418 (2023)
Circulating glucocorticoids increase during stress. Chronic stress, characterized by a sustained increase in serum levels of cortisol, has been associated in different cases with an increased risk of cancer and a worse prognosis. Glucocorticoids can
Externí odkaz:
https://doaj.org/article/ea3fbe4435834a9ca996059fd31fbce1
Autor:
Elena Obrador, Rosario Salvador-Palmer, Rafael López-Blanch, María Oriol-Caballo, Paz Moreno-Murciano, José M. Estrela
Publikováno v:
Cancers, Vol 14, Iss 15, p 3614 (2022)
N-acetylcysteine (NAC) is a direct Cys donor and a promoter of glutathione (GSH) synthesis. GSH regulates melanoma growth and NAC has been suggested to increase melanoma metastases in mice. We found that high therapeutic doses of NAC do not increase
Externí odkaz:
https://doaj.org/article/7f672648ceee4bd99dafa819123c0309
Publikováno v:
Antioxidants, Vol 10, Iss 12, p 2007 (2021)
Oxidative stress has been proposed as a major mechanism of damage to motor neurons associated with the progression of amyotrophic lateral sclerosis (ALS). Astrocytes are the most numerous glial cells in the central nervous system and, under physiolog
Externí odkaz:
https://doaj.org/article/6280733daa544987aac5703849a91389
Autor:
Elena Obrador, Rosario Salvador-Palmer, Rafael López-Blanch, Ryan W. Dellinger, José M. Estrela
Publikováno v:
Biomedicines, Vol 9, Iss 8, p 1000 (2021)
Charcot first described amyotrophic lateral sclerosis (ALS) between 1865 and 1874 as a sporadic adult disease resulting from the idiopathic progressive degeneration of the motor neuronal system, resulting in rapid, progressive, and generalized muscle
Externí odkaz:
https://doaj.org/article/8ab4a03fefb948afa35e99d091dcb469
Autor:
Elena Obrador, Rosario Salvador-Palmer, Rafael López-Blanch, Ali Jihad-Jebbar, Soraya L. Vallés, José M. Estrela
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12, p 6352 (2021)
Amyotrophic lateral sclerosis (ALS) is the most common neurodegenerative disease of the motor system. It is characterized by the degeneration of both upper and lower motor neurons, which leads to muscle weakness and paralysis. ALS is incurable and ha
Externí odkaz:
https://doaj.org/article/877ce670befc4a98a0d242df29d2e656
Autor:
Elena Obrador, Rosario Salvador-Palmer, Ali Jihad-Jebbar, Rafael López-Blanch, Thanh H. Dellinger, Ryan W. Dellinger, José M. Estrela
Publikováno v:
Antioxidants, Vol 10, Iss 3, p 492 (2021)
Natural polyphenols are organic chemicals which contain phenol units in their structures and possess antitumor properties. However, a key problem is their short half-life and low bioavailability under in vivo conditions. Pterostilbene (3,5-dimethoxy-
Externí odkaz:
https://doaj.org/article/df6d36b6df904d9587431c7d30c05079