Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Rafael Ikemori"'
Autor:
Paula Duch, Natalia Díaz-Valdivia, Rafael Ikemori, Marta Gabasa, Evette S. Radisky, Marselina Arshakyan, Sabrina Gea-Sorlí, Anna Mateu-Bosch, Paloma Bragado, Josep Lluís Carrasco, Hidetoshi Mori, Josep Ramírez, Cristina Teixidó, Noemí Reguart, Cristina Fillat, Derek C. Radisky, Jordi Alcaraz
Publikováno v:
Matrix Biology. 111:207-225
Tissue inhibitor of metalloproteinase-1 (TIMP-1) is an important regulator of extracellular matrix turnover that has been traditionally regarded as a potential tumor suppressor owing to its inhibitory effects of matrix metalloproteinases. Intriguingl
Autor:
Jordi Alcaraz, Noemí Reguart, Frank Hilberg, Cristina Fillat, Pere Gascon, Victor Ivo Peinado, Eduard Monsó, Manel Esteller, Luis M. Montuenga, Laura Soucek, Toni Jauset, Sabrina Gea-Sorli, Gemma Fuster, Manuel Castro, Sebastian Morán, Albert Marín, Iuliana-Cristiana Luis, Marselina Arshakyan, Paloma Bragado, Miguel Vizoso, Paula Duch, Marta Gabasa, Rafael Ikemori
Supplementary Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::598a79d2e19d534941a510814593f277
https://doi.org/10.1158/0008-5472.22425144.v1
https://doi.org/10.1158/0008-5472.22425144.v1
Autor:
Jordi Alcaraz, Noemí Reguart, Frank Hilberg, Cristina Fillat, Pere Gascon, Victor Ivo Peinado, Eduard Monsó, Manel Esteller, Luis M. Montuenga, Laura Soucek, Toni Jauset, Sabrina Gea-Sorli, Gemma Fuster, Manuel Castro, Sebastian Morán, Albert Marín, Iuliana-Cristiana Luis, Marselina Arshakyan, Paloma Bragado, Miguel Vizoso, Paula Duch, Marta Gabasa, Rafael Ikemori
Supplementary Figures S1-S7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56afb2c2cae0c40addd1202a97a32f0e
https://doi.org/10.1158/0008-5472.22425150
https://doi.org/10.1158/0008-5472.22425150
Autor:
Jordi Alcaraz, Noemí Reguart, Frank Hilberg, Cristina Fillat, Pere Gascon, Victor Ivo Peinado, Eduard Monsó, Manel Esteller, Luis M. Montuenga, Laura Soucek, Toni Jauset, Sabrina Gea-Sorli, Gemma Fuster, Manuel Castro, Sebastian Morán, Albert Marín, Iuliana-Cristiana Luis, Marselina Arshakyan, Paloma Bragado, Miguel Vizoso, Paula Duch, Marta Gabasa, Rafael Ikemori
Supplementary Material
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eec7c27161817940df5c49135183c49
https://doi.org/10.1158/0008-5472.22425147
https://doi.org/10.1158/0008-5472.22425147
Autor:
Jordi Alcaraz, Noemí Reguart, Frank Hilberg, Cristina Fillat, Pere Gascon, Victor Ivo Peinado, Eduard Monsó, Manel Esteller, Luis M. Montuenga, Laura Soucek, Toni Jauset, Sabrina Gea-Sorli, Gemma Fuster, Manuel Castro, Sebastian Morán, Albert Marín, Iuliana-Cristiana Luis, Marselina Arshakyan, Paloma Bragado, Miguel Vizoso, Paula Duch, Marta Gabasa, Rafael Ikemori
The tumor-promoting fibrotic stroma rich in tumor-associated fibroblasts (TAF) is drawing increased therapeutic attention. Intriguingly, a trial with the antifibrotic drug nintedanib in non–small cell lung cancer reported clinical benefits in adeno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7a12173d12743c4be33a01a3b0319fa
https://doi.org/10.1158/0008-5472.c.6511959.v1
https://doi.org/10.1158/0008-5472.c.6511959.v1
Autor:
Natalia Isabel Diaz Valdivia, Yago Juste Lanas, Alejandro Llorente, Rafael Ikemori, Alejandro Bernardo, Noemi Reguart, Jose M. Garcia Aznar, Jordi Alcaraz
Publikováno v:
Cancer Research. 83:5849-5849
Lung cancer is characterized by a stiff fibrotic microenvironment rich in activated/pro-fibrotic tumor-associated fibroblasts (TAFs). We previously reported a larger accumulation of TAFs in lung adenocarcinoma (ADC) compared to lung squamous cell car
Autor:
Paula Duch, Natalia Díaz-Valdivia, Marta Gabasa, Rafael Ikemori, Frank Hilberg, Noemí Reguart, Derek Radisky, Jordi Alcaraz
Publikováno v:
Cancer Research. 83:2356-2356
Adenocarcinoma (ADC) and Squamous Cell Carcinoma (SCC) are the most frequent histologic subtypes of lung cancer, and both are rich in activated/myofibroblast-like tumor-associated fibroblasts (TAFs). Nintedanib is a potent antifibrotic drug that targ
Autor:
Natalia Isabel Diaz Valdivia, Paula Duch, Rafael Ikemori, Eduard Monso, Noemi Reguart, Jordi Alcaraz
Publikováno v:
Cancer Research. 83:4597-4597
Background: Lung adenocarcinoma (ADC) and squamous cell carcinoma (SCC) are the most common histologic subtypes in lung cancer. Intriguingly, ADC and SCC exhibit distinct responses to the multi-tyrosine kinase inhibitor nintedanib and other antiangio
Autor:
Manel Esteller, Rafael Ikemori, Marselina Arshakyan, Luis M. Montuenga, Toni Jauset, Paula Duch, Pere Gascón, Frank Hilberg, Laura Soucek, Gemma Fuster, Sabrina Gea-Sorli, Miguel Vizoso, Cristina Fillat, Manuel Castro, Sebastian Moran, Eduard Monsó, Albert Marín, Victor I. Peinado, Paloma Bragado, Noemí Reguart, Iuliana-Cristiana Luis, Marta Gabasa, Jordi Alcaraz
Publikováno v:
Cancer Research. 80:276-290
The tumor-promoting fibrotic stroma rich in tumor-associated fibroblasts (TAF) is drawing increased therapeutic attention. Intriguingly, a trial with the antifibrotic drug nintedanib in non–small cell lung cancer reported clinical benefits in adeno
Autor:
Yago Juste-Lanas, Natalia Díaz-Valdivia, Alejandro Llorente, Rafael Ikemori, Alejandro Bernardo, Marselina Arshakyan, Carlos Borau, Josep Ramírez, José Carlos Ruffinelli, Ernest Nadal, Noemí Reguart, José M. García-Aznar, Jordi Alcaraz
Background The TGF-β1 transcription factor SMAD3 is epigenetically repressed in tumour-associated fibroblasts (TAFs) from lung squamous cell carcinoma (SCC) but not adenocarcinoma (ADC) patients, which elicits a compensatory increase in SMAD2 that r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b7ccd3dc5ec054a20e14ec1a42325d5
http://zaguan.unizar.es/record/124354
http://zaguan.unizar.es/record/124354