Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Rafael Godínez Fernández"'
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 8, p e1012357 (2024)
The experimental study and transplantation of pancreatic islets requires their isolation from the surrounding tissue, and therefore, from the vasculature. Under these conditions, avascular islets rely on the diffusion of peripheral oxygen and nutrien
Externí odkaz:
https://doaj.org/article/d6d25d52f68b4ec88b6c24f105ce8313
Publikováno v:
Islets
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Intra-islet communication via electrical, paracrine and autocrine signals, is highly dependent on the organization of cells within the islets and is key for an adequate response to changes in blood glucose and other stimuli. In spite of the fact that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e8a9f777c37b9b9bf179537ff29fe92
http://europepmc.org/articles/PMC8632330
http://europepmc.org/articles/PMC8632330
Publikováno v:
IFMBE Proceedings ISBN: 9783031182556
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6dd8f6c24ac9956e303f38df9475941
https://doi.org/10.1007/978-3-031-18256-3_22
https://doi.org/10.1007/978-3-031-18256-3_22
Autor:
Diego Alejandro Flores-Santillán, José Rafael Godínez-Fernández, Gerardo Jorge Félix-Martínez
Publikováno v:
IFMBE Proceedings ISBN: 9783031182556
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::659c66b157a27720386d267260644f54
https://doi.org/10.1007/978-3-031-18256-3_24
https://doi.org/10.1007/978-3-031-18256-3_24
Publikováno v:
Islets
We outline a general methodology based on computational optimization and experimental data to reconstruct human pancreatic islet architectures. By using the nuclei coordinates of islet cells obtained through DAPI staining, cell types identified by im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a08f0f96cafeb1ec18d75c109270e9
https://doi.org/10.1080/19382014.2020.1823178
https://doi.org/10.1080/19382014.2020.1823178
Publikováno v:
Endocrinología, Diabetes y Nutrición (English ed.). 67:333-341
Background It is estimated that 37% of Mexican adults have undiagnosed diabetes, and are therefore at high risk of developing the severe and devastating complications associated to it. In recent years, a variety of screening tools based on the charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e66c80bc4084120c8405bc6221e01a80
https://doi.org/10.1016/j.endien.2019.08.009
https://doi.org/10.1016/j.endien.2019.08.009
Publikováno v:
Journal of Visualized Experiments.
Structural properties of pancreatic islets are key for the functional response of insulin, glucagon, and somatostatin-secreting cells, due to their implications in intraislet communication via electric, paracrine, and autocrine signaling. In this pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af6274bfa5298dbd8a28d50577d744e
https://doi.org/10.3791/63351
https://doi.org/10.3791/63351
Akademický článek
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Akademický článek
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Publikováno v:
Health and Technology. 10:379-383
By using a computational model of a single human β-cell, in this work we analyze the effect of cell size on insulin secretion. The model includes an electric component capable of reproducing the electrical behavior of the human β-cell, a buffered d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::536110f53b20b43a0214f5642117309d
https://doi.org/10.1007/s12553-019-00350-3
https://doi.org/10.1007/s12553-019-00350-3