Výsledky vyhledávání - "Rafael G. Karam"

Akademický článek

Immunophenotyping lymphocyte and acute phase proteins in canine X-linked muscular dystrophy

Autor: DILAYLA K. DE ABREU, JANAINA M. MONTEIRO, CAROLINA C. SOUZA, RAFAEL G. KARAM, RENATA A. FERNANDES, THAIS B. LESSA, JOSÉ J. FAGLIARI, MARIA ANGELICA MIGLINO, CARLOS EDUARDO AMBROSIO

Publikováno v: Anais da Academia Brasileira de Ciências, Vol 90, Iss 3, Pp 2977-2990

Abstract Duchenne Muscular Dystrophy (DMD) is the most common X-linked muscular disease affecting humans. The Golden Retriever Muscular Dystrophy model (GRMD) is considerthe most suitable for several studies. This assay aims to quantify lymphocyte su

Externí odkaz: https://doaj.org/article/ace0d1ddc5704a78a6cfd9381f9d7b8b

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Exploring neuropsychological predictors of ADHD remission or persistence during adulthood

Autor: Diego L. Rovaris, Rafael G. Karam, Eugenio H. Grevet, Luis Augusto Rohde, Claiton H.D. Bau, Paula O. Guimarães-da-Silva, Katiane L. Silva

Publikováno v: Cognitive Neuropsychiatry. 23:321-328

Attention Deficit Hyperactivity Disorder (ADHD) is a neuropsychiatric disorder characterized by symptoms of inattention, hyperactivity and impulsivity (APA, 2013) with a prevalence of 5.3% in child...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa3ebb0b6d0369ec13fbdcf4448a11a
https://doi.org/10.1080/13546805.2018.1506324

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Further replication of the synergistic interaction between LPHN3 and the NTAD gene cluster on ADHD and its clinical course throughout adulthood

Autor: Diego L. Rovaris, Eugenio H. Grevet, Eduardo S. Vitola, Bruna Santos da Silva, Stefania Pigatto Teche, Renata B. Cupertino, Luis Augusto Rohde, Nina Roth Mota, Jaqueline Bohrer Schuch, Claiton H.D. Bau, Rafael G. Karam, Cristina Winkler, Djenifer B. Kappel

Publikováno v: Progress in Neuro-Psychopharmacology and Biological Psychiatry. 79:120-127

Attention-Deficit/Hyperactivity Disorder (ADHD) is a common and highly heritable neuropsychiatric disorder. Despite the high heritability, the unraveling of specific genetic factors related to ADHD is hampered by its considerable genetic complexity.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::777d47b24d2a02287ab7777f277c3635
https://doi.org/10.1016/j.pnpbp.2017.06.011

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Autor: Claiton H.D. Bau, Diana Müller, Verônica Contini, Rafael G. Karam, Marcelo M. Victor, Nina Roth Mota, Cibele Edom Bandeira, B S da Silva, Eugenio H. Grevet, Djenifer B. Kappel, Jaqueline Bohrer Schuch, Renata B. Cupertino, Luiz Rohde, Diego L. Rovaris

Publikováno v: Molecular Psychiatry, 23, 6, pp. 1446-1452
Molecular Psychiatry, 23, 1446-1452

Experimental studies have demonstrated that methylphenidate (MPH) modulates the synaptic vesicle trafficking and synaptotagmin-1 (SytI) mRNA levels. SytI is a regulatory protein of the SNARE complex, a neurotransmitter exocytosis mediator. Despite th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55933194b27ddc3624741242d4980b3e
https://doi.org/10.1038/mp.2017.90

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Methylphenidate Alters Functional Connectivity of Default Mode Network in Drug-Naive Male Adults With ADHD

Autor: Bruna Bressan Valentini, Alessandro André Mazzola, Neivo da Silva, Eugenio H. Grevet, Marcelo M. Victor, João Ricardo Sato, Vitor Breda, Rafael G. Karam, Felipe Almeida Picon, Luis Augusto Rohde, Katiane L. Silva, Leonardo Modesti Vedolin, Maurício Anés, Renata B. Cupertino, Claiton H.D. Bau

Publikováno v: Journal of attention disorders. 24(3)

Objective: This study evaluated the hypothesis that methylphenidate immediate release (MPH-IR) treatment would improve Default Mode Network (DMN) within-connectivity. Method: Resting-state functional connectivity of the main nodes of DMN was evaluate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c064fe2f8b7679ccf5296925a8a3f7
https://pubmed.ncbi.nlm.nih.gov/30526190

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Pleiotropic effects of Chr15q25 nicotinic gene cluster and the relationship between smoking, cognition and ADHD

Autor: Djenifer B. Kappel, Rafael G. Karam, Nina Roth Mota, Eugenio H. Grevet, Evelise R. Polina, Luis Augusto Rohde, Jaqueline Bohrer Schuch, Melanie J. White, Renata B. Cupertino, Claiton H.D. Bau, Paula O. Guimarães-da-Silva, Katiane L. Silva, Carlos A.I. Salgado, Diego L. Rovaris

Publikováno v: Journal of Psychiatric Research. 80:73-78

Polymorphisms in the CHRNA5-CHRNA3-CHRNB4 gene cluster (Chr15q25) have been robustly associated with nicotine dependence, including genome-wide studies, as well as with cognitive and neuropsychological measures. In addition, cognitive processes can b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2dc0bccccfd786116dc88bcde3a0139
https://doi.org/10.1016/j.jpsychires.2016.06.002

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Predictors of persistence of ADHD into adulthood: a systematic review of the literature and meta-analysis

Autor: Rafael G. Karam, Eugenio H. Grevet, Alex Vicente Spadini, Christian Kieling, Claiton H.D. Bau, Luis Augusto Rohde, Diego L. Rovaris, Arthur Caye

Publikováno v: European Child & Adolescent Psychiatry. 25:1151-1159

Attention-deficit/hyperactivity disorder (ADHD) is traditionally conceptualized as a neurodevelopmental disorder that continues into adulthood in up to half of diagnosed cases. In light of current evidence, factors associated with the course of the d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54371671b29ffb72848d5e249ef82b00
https://doi.org/10.1007/s00787-016-0831-8

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NCAM1‐TTC12‐ANKK1‐DRD2 gene cluster and the clinical and genetic heterogeneity of adults with ADHD

Autor: Nina Roth Mota, Luis Augusto Rohde, Djenifer B. Kappel, Diego L. Rovaris, Felipe Almeida Picon, Rafael G. Karam, Carlos A.I. Salgado, Eugenio H. Grevet, Claiton H.D. Bau, Eduardo S. Vitola

Publikováno v: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 168:433-444

Dysfunctions of the dopaminergic system have been implicated on the etiology of Attention Deficit/Hyperactivity Disorder (ADHD). Meta-analyses addressing the association of the dopamine receptor D2 (DRD2) gene and ADHD were inconclusive due to excess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3faeb197b35382c273002bf4e07c9c07
https://doi.org/10.1002/ajmg.b.32317

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Trajectories of attention-deficit/hyperactivity disorder dimensions in adults

Autor: Katiane L. Silva, M. Meller, Rafael G. Karam, Nina Roth Mota, Luiz Rohde, Vitor Breda, Carlos A.I. Salgado, Claiton H.D. Bau, Marcelo M. Victor, Felipe Almeida Picon, Eduardo S. Vitola, Diego Luiz Rovaris, Eugenio H. Grevet

Publikováno v: Acta psychiatrica Scandinavica. 136(2)

Objective There is a lack of available information on the trajectories of attention-deficit/hyperactivity disorder (ADHD) dimensions during adulthood. This study investigates the course and the predictors of change for each ADHD domain in a clinical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5ced566703a3b5367112e715993a7ab
https://pubmed.ncbi.nlm.nih.gov/28555716

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