Zobrazeno 1 - 2
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pro vyhledávání: '"Rafael G de Rubio"'
Autor:
Kyun-Do Kim, Seyeon Bae, Tara Capece, Hristina Nedelkovska, Rafael G. de Rubio, Alan V. Smrcka, Chang-Duk Jun, Woojin Jung, Byeonghak Park, Tae-il Kim, Minsoo Kim
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Regulatory T cells (Tregs) promote immune suppression in the tumour. Here, the authors show that Tregs suppress cytotoxic T lymphocyte (CTL) activity by impairing Ca2+ signalling and that adoptive transfer of CTLs engineered with an optogenetic contr
Externí odkaz:
https://doaj.org/article/eaff6961123b44e39ab2cbba3d2edb63
Autor:
Kyun Do Kim, Seyeon Bae, Tara Capece, Hristina Nedelkovska, Rafael G de Rubio, Alan V Smrcka, Woojin Jung, Byeonghak Park, Tae-il Kim, Sonal Srikanth, Yousang Gwack, Minsoo Kim
Publikováno v:
The Journal of Immunology. 198:126.3-126.3
Adoptive cell transfer utilizing tumor-targeting cytotoxic T lymphocytes (CTLs) is one of the most effective immunotherapies against hematological malignancies, but significant clinical success has not yet been achieved in solid tumors due in part to