Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Rafael Cantera"'
Autor:
Magdalena Fernandez-Acosta, Juan I. Romero, Guillermo Bernabó, Giovanna M. Velázquez-Campos, Nerina Gonzalez, M. Lucía Mares, Santiago Werbajh, L. Amaranta Avendaño-Vázquez, Gerald N. Rechberger, Ronald P. Kühnlein, Cristina Marino-Buslje, Rafael Cantera, Carolina Rezaval, M. Fernanda Ceriani
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-25 (2022)
Abstract Background Lipid homeostasis is an evolutionarily conserved process that is crucial for energy production, storage and consumption. Drosophila larvae feed continuously to achieve the roughly 200-fold increase in size and accumulate sufficien
Externí odkaz:
https://doaj.org/article/060c6bc5f2bf4c0083dfbf05f140558d
Autor:
Flavio Pazos Obregón, Diego Silvera, Pablo Soto, Patricio Yankilevich, Gustavo Guerberoff, Rafael Cantera
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract The function of most genes is unknown. The best results in automated function prediction are obtained with machine learning-based methods that combine multiple data sources, typically sequence derived features, protein structure and interact
Externí odkaz:
https://doaj.org/article/aa2beb56cd7547488d1f889b69977730
Autor:
Flavio Pazos Obregón, Martín Palazzo, Pablo Soto, Gustavo Guerberoff, Patricio Yankilevich, Rafael Cantera
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-8 (2019)
Abstract Background Assembly and function of neuronal synapses require the coordinated expression of a yet undetermined set of genes. Previously, we had trained an ensemble machine learning model to assign a probability of having synaptic function to
Externí odkaz:
https://doaj.org/article/7a614cebbe91412a84dee9f1c9f22d52
Publikováno v:
Biology Open, Vol 9, Iss 8 (2020)
Environmental factors such as the availability of oxygen are instructive cues that regulate stem cell maintenance and differentiation. We used a genetically encoded biosensor to monitor the hypoxic state of neural cells in the larval brain of Drosoph
Externí odkaz:
https://doaj.org/article/20eb0dff290a4c10a9d4f0be87c5ffbc
Autor:
Tvisha Misra, Martin Baccino-Calace, Felix Meyenhofer, David Rodriguez-Crespo, Hatice Akarsu, Ricardo Armenta-Calderón, Thomas A. Gorr, Christian Frei, Rafael Cantera, Boris Egger, Stefan Luschnig
Publikováno v:
Biology Open, Vol 6, Iss 2, Pp 296-304 (2017)
Cells experience different oxygen concentrations depending on location, organismal developmental stage, and physiological or pathological conditions. Responses to reduced oxygen levels (hypoxia) rely on the conserved hypoxia-inducible factor 1 (HIF-1
Externí odkaz:
https://doaj.org/article/e72686a3521d49ca9a1f979342460521
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Here we report on ultrastructural features of brain synapses in the fly Drosophila melanogaster and outline a perspective for the study of their functional significance. Images taken with the aid of focused ion beam-scanning electron microscopy (EM)
Externí odkaz:
https://doaj.org/article/4adcecf81f4a48ec8dbc327de8cbaf45
Autor:
María José Ferreiro, Coralia Pérez, Mariana Marchesano, Santiago Ruiz, Angel Caputi, Pedro Aguilera, Rosa Barrio, Rafael Cantera
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2018)
Key scientific discoveries have resulted from genetic studies of Drosophila melanogaster, using a multitude of transgenic fly strains, the majority of which are constructed in a genetic background containing mutations in the white gene. Here we repor
Externí odkaz:
https://doaj.org/article/a5824d7a2f15430598d5dc88cc33d927
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97703 (2014)
Regulation of transcription is one of the mechanisms involved in animal development, directing changes in patterning and cell fate specification. Large temporal data series, based on microarrays across the life cycle of the fly Drosophila melanogaste
Externí odkaz:
https://doaj.org/article/620349a84c53477f8a0a90a5867871de
Autor:
Santiago Ruiz, Maria Jose Ferreiro, Kerstin I Menhert, Gabriela Casanova, Alvaro Olivera, Rafael Cantera
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67161 (2013)
Previous studies have shown that the morphology of the neuromuscular junction of the flight motor neuron MN5 in Drosophila melanogaster undergoes daily rhythmical changes, with smaller synaptic boutons during the night, when the fly is resting, than
Externí odkaz:
https://doaj.org/article/77c3d156a9e94c6bb434718ca2d6f883
Autor:
Malgorzata Pokrzywa, Ingrid Dacklin, Monika Vestling, Dan Hultmark, Erik Lundgren, Rafael Cantera
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14343 (2010)
BACKGROUND: A functional link has been established between the severe neurodegenerative disorder Familial amyloidotic polyneuropathy and the enhanced propensity of the plasma protein transthyretin (TTR) to form aggregates in patients with single poin
Externí odkaz:
https://doaj.org/article/fd885be3e4c04ad9822ffb4137abad1c