Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Rafael Bertoni da Silveira"'
Autor:
Andrea Senff-Ribeiro, Silvio Sanches Veiga, Luiza Helena Gremski, Waldemiro Gremski, Rafael Bertoni da Silveira, Oldemir Carlos Mangili, Valéria Pereira Ferrer, Fernando Hitomi Matsubara, Daniele Chaves-Moreira, Ana Carolina M. Wille, Dilza Trevisan-Silva, Olga Meiri Chaim
Publikováno v:
Toxins, Vol 3, Iss 3, Pp 309-344 (2011)
Venomous animals use their venoms as tools for defense or predation. These venoms are complex mixtures, mainly enriched of proteic toxins or peptides with several, and different, biological activities. In general, spider venom is rich in biologically
Externí odkaz:
https://doaj.org/article/b4f788f7b9f6452dae703239b21e519b
Autor:
Valéria Pereira Ferrer, Thiago Lopes de Mari, Luiza Helena Gremski, Dilza Trevisan Silva, Rafael Bertoni da Silveira, Waldemiro Gremski, Olga Meiri Chaim, Andrea Senff-Ribeiro, Helena Bonciani Nader, Silvio Sanches Veiga
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 5, p e2206 (2013)
Loxoscelism is the designation given to clinical symptoms evoked by Loxosceles spider's bites. Clinical manifestations include skin necrosis with gravitational spreading and systemic disturbs. The venom contains several enzymatic toxins. Herein, we d
Externí odkaz:
https://doaj.org/article/ffef68a542e1411a99a38218ac139cda
Publikováno v:
Current Drug Targets. 13:1072-1082
One of the major issues facing anticancer research relies on the intrinsic inability of tumor cells to undergo apoptosis. Additionally, the development of cancer resistance to standard therapy and the great heterogeneity associated with frequent muta
Autor:
Rafael Bertoni da Silveira, Olga Meiri Chaim, Fernando Hitomi Matsubara, Daniele Chaves-Moreira, Dilza Trevisan-Silva, Andrea Senff-Ribeiro, Valéria Pereira Ferrer, Silvio Sanches Veiga, Oldemir C. Mangili, Ana Carolina Martins Wille, Luiza Helena Gremski, Waldemiro Gremski
Publikováno v:
Toxins, Vol 3, Iss 3, Pp 309-344 (2011)
Toxins
Toxins
Venomous animals use their venoms as tools for defense or predation. These venoms are complex mixtures, mainly enriched of proteic toxins or peptides with several, and different, biological activities. In general, spider venom is rich in biologically
Autor:
Silvio Sanches Veiga, Waldemiro Gremski, Luiza Helena Gremski, Katia C. Barbaro, Gabriel Otto Meissner, Dilza Trevisan-Silva, Oldemir C. Mangili, Olga Meiri Chaim, Andrea Senff-Ribeiro, Rafael Bertoni da Silveira
Publikováno v:
Biochimie. 92:21-32
Brown spiders have a worldwide distribution, and their venom has a complex composition containing many different molecules. Herein, we report the existence of a family of astacin-like metalloprotease toxins in Loxosceles intermedia venom, as well as
Autor:
Célia Regina Cavichiolo Franco, Helena B. Nader, Carl P. Dietrich, Katia Sabrina Paludo, Silvio Sanches Veiga, Roger Chammas, Hugo A.O. RochaH.A.O. Rocha, E. S. Trindade, Rafael Bertoni da Silveira
Publikováno v:
Biochemistry and Cell Biology. 87:677-686
α5β1integrin from both wild-type CHO cells (CHO-K1) and deficient in proteoglycan biosynthesis (CHO-745) is post-translationally modified by glycosaminoglycan chains. We demonstrated this using [35S]sulfate metabolic labeling of the cells, enzymati
Autor:
Olga Meiri Chaim, Oldemir C. Mangili, Juliana de Moura, Rafael Bertoni da Silveira, Lucélia Donatti, Youssef Bacila Sade, Waldemiro Gremski, Luiza Helena Gremski, Daniele Chaves-Moreira, Silvio Sanches Veiga, Andrea Senff-Ribeiro, Katia Sabrina Paludo
Publikováno v:
Journal of Cellular Biochemistry. 107:655-666
Brown spiders have world-wide distribution and are the cause of health problems known as loxoscelism. Necrotic cutaneous lesions surrounding the bites and less intense systemic signs like renal failure, DIC, and hemolysis were observed. We studied mo
Autor:
Thais R. M. Filippo, Renato A. Mortara, Rafael Bertoni da Silveira, Vivien Jane Coulson-Thomas, Yvette M. Coulson-Thomas, Marimelia Porcionatto, Helena B. Nader
Publikováno v:
Journal of Neuroscience Methods. 171:19-29
Injury to the CNS of vertebrates leads to the formation of a glial scar and production of inhibitory molecules, including chondroitin sulphate proteoglycans. Various studies suggest that the sugar component of the proteoglycan is responsible for the
Autor:
Katia Sabrina Paludo, Silvio S. Veiga, Olga Meiri Chaim, Paulo Henrique da Silva, Oldemir C. Mangili, Luiza Helena Gremski, Rafael Bertoni da Silveira, Andrea Senff-Ribeiro, Waldemiro Gremski
Publikováno v:
Biotechnology Advances. 26:210-218
Loxoscelism (the term used to define accidents by the bite of brown spiders) has been reported worldwide. Clinical manifestations following brown spider bites are frequently associated with skin degeneration, a massive inflammatory response at the in
Autor:
Olga Meiri Chaim, Ana Carolina Martins Wille, Oldemir C. Mangili, Helena B. Nader, Rafael Bertoni da Silveira, Dilza Trevisan Silva, Waldemiro Gremski, Célia Regina Cavichiolo Franco, Silvio Sanches Veiga, Marcia Helena Appel, Leny Toma, Carl P. Dietrich
Publikováno v:
Biochemical Journal. 406:355-363
Injuries caused by brown spiders (Loxosceles genus) are associated with dermonecrotic lesions with gravitational spreading and systemic manifestations. The venom has a complex composition containing many different toxins, of which metalloproteases ha