Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Rafał Hołubowicz"'
Autor:
Elliot H. Choi, Susie Suh, Avery E. Sears, Rafał Hołubowicz, Sanjay R. Kedhar, Andrew W. Browne, Krzysztof Palczewski
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 8, Pp 1678-1690 (2023)
Abstract Genome-editing technologies have ushered in a new era in gene therapy, providing novel therapeutic strategies for a wide range of diseases, including both genetic and nongenetic ocular diseases. These technologies offer new hope for patients
Externí odkaz:
https://doaj.org/article/d58bc19db29b4a7e9532ad192a5f1a3b
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract The C1q superfamily includes proteins involved in innate immunity, insulin sensitivity, biomineralization and more. Among these proteins is otolin-1, which is a collagen-like protein that forms a scaffold for the biomineralization of inner e
Externí odkaz:
https://doaj.org/article/2cf02340cb784622ba8f3afa3e8a2df4
Autor:
Marta Kolonko, Katarzyna Ożga, Rafał Hołubowicz, Michał Taube, Maciej Kozak, Andrzej Ożyhar, Beata Greb-Markiewicz
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162950 (2016)
Methoprene tolerant protein (Met) has recently been confirmed as the long-sought juvenile hormone (JH) receptor. This protein plays a significant role in the cross-talk of the 20-hydroxyecdysone (20E) and JH signalling pathways, which are important f
Externí odkaz:
https://doaj.org/article/4623b73d2a3b4b4f9160b541166b3456
Autor:
Elżbieta Wieczorek, Sylwia Kędracka-Krok, Katarzyna Sołtys, Urszula Jankowska, Rafał Hołubowicz, Justyna Seliga, Andrzej Ożyhar
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160536 (2016)
Ageing and mutations of transthyretin (TTR), the thyroid hormones and retinol transporting protein lead to amyloidosis by destabilizing the structure of TTR. Because protein structure is regulated through posttranslational modifications, we investiga
Externí odkaz:
https://doaj.org/article/b3ecf10fe1ec49bc81553c611b16b45f
Autor:
Klaudia Bielak, Rafał Hołubowicz, Anna Zoglowek, Andrzej Żak, Paweł Kędzierski, Andrzej Ożyhar, Piotr Dobryszycki
Publikováno v:
International Journal of Biological Macromolecules. 209:1032-1047
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bc2d80707413ec29bc3ac703f5c076e
https://doi.org/10.1016/j.ijbiomac.2022.04.088
https://doi.org/10.1016/j.ijbiomac.2022.04.088
Autor:
Rafał Hołubowicz, Krzysztof Palczewski
Publikováno v:
Trends in Molecular Medicine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::203c8ede5d4e76b4e1656a1177d9aa0b
https://doi.org/10.1016/j.molmed.2023.04.008
https://doi.org/10.1016/j.molmed.2023.04.008
Autor:
Monika Szefczyk, Katarzyna Ożga, Magda Drewniak-Świtalska, Ewa Rudzińska-Szostak, Rafał Hołubowicz, Andrzej Ożyhar, Łukasz Berlicki
Publikováno v:
RSC advances. 12(8)
The key issue in the research on foldamers remains the understanding of the relationship between the monomers structure and conformational properties at the oligomer level. In peptidomimetic foldamers, the main goal of which is to mimic the structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9145d8c9bef4e748b03594ef9538a71
https://pubmed.ncbi.nlm.nih.gov/35425498
https://pubmed.ncbi.nlm.nih.gov/35425498
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 9085, p 9085 (2021)
Volume 22
Issue 16
International Journal of Molecular Sciences, Vol 22, Iss 9085, p 9085 (2021)
Otolin-1 is a scaffold protein of otoliths and otoconia, calcium carbonate biominerals from the inner ear. It contains a gC1q domain responsible for trimerization and binding of Ca2+. Knowledge of a structure–function relationship of gC1q domain of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51b25e5827d72068264daec00c881038
Autor:
Agnieszka Gizak, Piotr Dobryszycki, Janusz Wiśniewski, Rafał Hołubowicz, James A. McCubrey, Dariusz Rakus, Michal Pirog
Publikováno v:
Oncotarget
Muscle fructose 1,6-bisphosphatase (FBP2), besides being a regulatory enzyme of glyconeogenesis also protects mitochondria against calcium stress and plays a key role in regulation of the cell cycle, promoting cardiomyocytes survival. However, in can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16f672f6b4098ed84b1c71f43ac56cad
https://doi.org/10.18632/oncotarget.23271
https://doi.org/10.18632/oncotarget.23271
Autor:
Rafał Hołubowicz, Mirosława Różycka, Zbigniew Szewczuk, Aleksandra Porębska, Piotr Dobryszycki, Andrzej Ożyhar
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 34(5)
Dentin matrix protein 1 (DMP1) is an acidic, extracellular matrix protein essential for biomineralization of calcium phosphate, in bone and dentin. It is proteolytically processed into two fragments, 44K and 56K. Recently, the presence of DMP1 was no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c24f01991a815ba78724ec6ec2cfb7
https://pubmed.ncbi.nlm.nih.gov/32190922
https://pubmed.ncbi.nlm.nih.gov/32190922