Zobrazeno 1 - 10
of 580
pro vyhledávání: '"Raf1"'
Publikováno v:
Case Reports in Oncology, Vol 17, Iss 1, Pp 960-965 (2024)
Introduction: Here, we report the first case of a soft tissue tumor with a PAK2::RAF1 fusion. Case Presentation: The patient was an 11-year-old female presenting with a 5 cm intramuscular mass in the lower leg. Microscopic examination revealed a mito
Externí odkaz:
https://doaj.org/article/8d7af6e1416242ea86eac67814fc0438
Publikováno v:
Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-16 (2024)
Abstract Background Sterigmatocystin (STE) is a mycotoxin widely found in contaminated food and foodstuffs, and excessive long-term exposure to STE is associated with several health issues, including infertility. However, there is little information
Externí odkaz:
https://doaj.org/article/a231959352a84da2a766db69034314df
Autor:
Yuzhao Liu, Xuesong Fan, Kun Qian, Changshun Wu, Laibo Zhang, Lin Yuan, Zhentao Man, Shuai Wu, Ping Li, Xianquan Wang, Wei Li, Yuanqing Zhang, Shui Sun, Chenxi Yu
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
BackgroundDevelopmental Dysplasia of the Hip (DDH) is a skeletal disorder where late-presenting forms often escape early diagnosis, leading to limb and pain in adults. The genetic basis of DDH is not fully understood despite known genetic predisposit
Externí odkaz:
https://doaj.org/article/0b842f0af8d24511a908c9ebd64dc0bd
Publikováno v:
World Journal of Surgical Oncology, Vol 21, Iss 1, Pp 1-9 (2023)
Abstract Background Endometrial carcinoma (EC) is one of the world’s typical female reproductive tract malignancies, mostly occurring in postmenopausal women. Many reports have confirmed that long non-coding RNA SOX21 antisense RNA1 (lncRNA SOX21-A
Externí odkaz:
https://doaj.org/article/ca94da5aff9947a0aeada34fb2571639
Autor:
HaiFeng Jiang, WeiChao Su, HaiXing Wang, ChunYing Luo, YaTao Wang, LinJun Zhang, LingTao Luo, ZeBin Lu, DongYan Shen, GuoQiang Su
Publikováno v:
Heliyon, Vol 10, Iss 3, Pp e24807- (2024)
Colorectal Carcinoma (CRC) is one of the most common malignant tumors of the digestive tract, with a high mortality rate. DPY30 is one of the core subunits of the histone methyltransferase complex, which was involved in many cancer processes. However
Externí odkaz:
https://doaj.org/article/6f44af60ad41465db582a72e62818463
Autor:
Lino Rohrer, Corinna Spohr, Carina Beha, Ricarda Griffin, Sandra Braun, Sebastian Halbach, Tilman Brummer
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-22 (2023)
Abstract The dimerization of RAF kinases represents a key event in their activation cycle and in RAS/ERK pathway activation. Genetic, biochemical and structural approaches provided key insights into this process defining RAF signaling output and the
Externí odkaz:
https://doaj.org/article/a88084baf5c14ea48da77da0940320a0
Publikováno v:
Precision Medical Sciences, Vol 12, Iss 2, Pp 113-120 (2023)
Abstract RAF1 (c‐raf) has been known as an important tumor‐promoter in many cancers. However, the regulatory mechanisms affecting RAF1 expressions are rarely reported. This study aimed to predict the candidate miRNAs of RAF1 gene and verify their
Externí odkaz:
https://doaj.org/article/188757dbb8664d929cfc6b2a59472090
Autor:
Samantha Wong, Yu Xuan Tan, Abigail Yi Ting Loh, Kiat Yi Tan, Hane Lee, Zainab Aziz, Stanley F Nelson, Engin Özkan, Hülya Kayserili, Nathalie Escande‐Beillard, Bruno Reversade
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 5, Pp 1-15 (2023)
Abstract Somatic and germline gain‐of‐function point mutations in RAF, one of the first oncogenes to be discovered in humans, delineate a group of tumor‐prone syndromes known as the RASopathies. In this study, we document the first human phenot
Externí odkaz:
https://doaj.org/article/12fc7fb5e634482b982be6cd3b0c8a2c
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Akademický článek
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