Molecular and cellular signatures underlying superior immunity against Bordetella pertussis upon pulmonary vaccination.

Autor: Raeven RH; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands.; Division of Drug Delivery Technology, Cluster BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden, The Netherlands., Brummelman J; Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.; Department of Infectious Diseases and Immunology, Utrecht University, Utrecht, The Netherlands., Pennings JLA; Centre for Health Protection, National Institute for Public Health and the Environment, Bilthoven, The Netherlands., van der Maas L; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands., Helm K; Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands., Tilstra W; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands., van der Ark A; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands., Sloots A; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands., van der Ley P; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands., van Eden W; Department of Infectious Diseases and Immunology, Utrecht University, Utrecht, The Netherlands., Jiskoot W; Division of Drug Delivery Technology, Cluster BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden, The Netherlands., van Riet E; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands., van Els CA; Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands., Kersten GF; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands.; Division of Drug Delivery Technology, Cluster BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden, The Netherlands., Han WG; Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands., Metz B; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands.

Publikováno v: Mucosal immunology [Mucosal Immunol] 2018 May; Vol. 11 (3), pp. 979-993. Date of Electronic Publication: 2017 Sep 20.

Bordetella pertussis outer membrane vesicle vaccine confers equal efficacy in mice with milder inflammatory responses compared to a whole-cell vaccine.

Autor: Raeven RH; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands.; Division of Drug Delivery Technology, Leiden Academic Centre for Drug Research, Leiden, The Netherlands., Brummelman J; Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands., Pennings JL; Centre for Health Protection (GZB), National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands., van der Maas L; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands., Tilstra W; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands., Helm K; Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands., van Riet E; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands., Jiskoot W; Division of Drug Delivery Technology, Leiden Academic Centre for Drug Research, Leiden, The Netherlands., van Els CA; Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands., Han WG; Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands., Kersten GF; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands.; Division of Drug Delivery Technology, Leiden Academic Centre for Drug Research, Leiden, The Netherlands., Metz B; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands.

Publikováno v: Scientific reports [Sci Rep] 2016 Dec 01; Vol. 6, pp. 38240. Date of Electronic Publication: 2016 Dec 01.

Transcriptome signature for dampened Th2 dominance in acellular pertussis vaccine-induced CD4(+) T cell responses through TLR4 ligation.

Autor: Brummelman J; Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.; Department of Infectious Diseases and Immunology, Utrecht University, The Netherlands., Raeven RH; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands., Helm K; Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands., Pennings JL; Centre for Health Protection, National Institute for Public Health and the Environment, Bilthoven, The Netherlands., Metz B; Institute for Translational Vaccinology (Intravacc), Bilthoven, The Netherlands., van Eden W; Department of Infectious Diseases and Immunology, Utrecht University, The Netherlands., van Els CA; Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands., Han WG; Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.

Publikováno v: Scientific reports [Sci Rep] 2016 Apr 27; Vol. 6, pp. 25064. Date of Electronic Publication: 2016 Apr 27.

Molecular signatures of the evolving immune response in mice following a Bordetella pertussis infection.

Autor: Raeven RH; Intravacc, Bilthoven, The Netherlands; Division of Drug Delivery Technology, Leiden Academic Centre for Drug Research, Leiden, The Netherlands., Brummelman J; Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands., Pennings JL; Centre for Health Protection (GZB), National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands., Nijst OE; Intravacc, Bilthoven, The Netherlands., Kuipers B; Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands., Blok LE; Intravacc, Bilthoven, The Netherlands., Helm K; Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands., van Riet E; Intravacc, Bilthoven, The Netherlands., Jiskoot W; Division of Drug Delivery Technology, Leiden Academic Centre for Drug Research, Leiden, The Netherlands., van Els CA; Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands., Han WG; Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands., Kersten GF; Intravacc, Bilthoven, The Netherlands; Division of Drug Delivery Technology, Leiden Academic Centre for Drug Research, Leiden, The Netherlands., Metz B; Intravacc, Bilthoven, The Netherlands.

Publikováno v: PloS one [PLoS One] 2014 Aug 19; Vol. 9 (8), pp. e104548. Date of Electronic Publication: 2014 Aug 19 (Print Publication: 2014).