Zobrazeno 1 - 10 of 13 pro vyhledávání: '"Raeesa A. Mohamad"'
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Akademický článek
Hepatoprotective Role of α-Lipoic acid and Thymoquinone in Acetaminophen- Induced Liver Injury: Down-Regulation of COX-2 and flt-1 Expression
Autor: Nawal M. Al-Rasheed, Laila Fadda, Nouf M. Al-Rasheed, Iman H. Hasan, Hanaa M. Ali, Musaed Al-Fayez, Raeesa A. Mohamad
Publikováno v: Brazilian Archives of Biology and Technology, Vol 60 (2017)
ABSTRACT Acetaminophen (APAP) is a widely-used analgesic, while toxic doses of which induce liver injury. Inducible cyclooxygenase-2 (COX-2) is derived prostaglandins which play an anti-inflammatory role in acetaminophen-induced hepatotoxicity. Selec
Externí odkaz: https://doaj.org/article/e0e251b456f34a73972c11451db5335b
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2
Biotin, coenzyme Q10, and their combination ameliorate aluminium chloride-induced Alzheimer's disease via attenuating neuroinflammation and improving brain insulin signaling
Autor: Amirah Alotaibi, Hazar Yacoub, Sadeem Alaraidh, Raeesa A. Mohamad, Shaykhah Albuhayri, Hala A. Attia, Maha A. Al-Amin
Publikováno v: Journal of biochemical and molecular toxicologyREFERENCES.
Insulin is important for brain function and neuronal survival. Insulin signaling is initiated by the phosphorylation of insulin receptor substrate-1 (IRS-1) at tyrosine (pTyr) residue. However, IRS-1 is inhibited by phosphorylation at serine (pSer).
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86bde5048fd8fc04dbc02d36a5af5e17
https://pubmed.ncbi.nlm.nih.gov/32383521
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3
Sitagliptin attenuates myocardial apoptosis via activating LKB-1/AMPK/Akt pathway and suppressing the activity of GSK-3β and p38α/MAPK in a rat model of diabetic cardiomyopathy
Autor: Nouf T. Al-Damry, Hala A. Attia, Raeesa A. Mohamad, Nawal M. Al-Rasheed, Nouf M. Al-Rasheed, Nduna Dizmiri, Maha A. Al-Amin, Muhammad Atteya
Publikováno v: Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 107
The present study aimed to investigate the protective effect of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on diabetic cardiomyopathy (DCM)-associated apoptosis and if this effect is mediated via modulating the activity of the survival kinases;
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e070b8b38128dba0960516cbe895746
https://pubmed.ncbi.nlm.nih.gov/30099338
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4
Vitamin D attenuates pro-inflammatory TNF-α cytokine expression by inhibiting NF-кB/p65 signaling in hypertrophied rat hearts
Autor: Nouf M. Al-Rasheed, Raeesa A. Mohamad, Maha A. Al-Amin, Hanaa N. Al-Ajmi, Iman H. Hasan, Yieldez A. Bassiouni, Nawal M. Al-Rasheed
Publikováno v: Journal of Physiology and Biochemistry. 71:289-299
A growing body of evidence suggests that immune activation and inflammatory mediators may play a key role in the development and progression of left ventricle (LV) hypertrophy. The present study was designed to test the hypothesis that the cardioprot
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78ac04cbb8eebdc72e502d5b7d6faa5c
https://doi.org/10.1007/s13105-015-0412-1
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5
Hepatoprotective Role of α-Lipoic acid and Thymoquinone in Acetaminophen- Induced Liver Injury: Down-Regulation of COX-2 and flt-1 Expression
Autor: Iman H. Hasan, Raeesa A. Mohamad, Musaed Alfayez, Nawal M. Al-Rasheed, Hanaa M. Ali, Nouf M. Al-Rasheed, Laila M. Fadda
Publikováno v: Brazilian Archives of Biology and Technology, Volume: 60, Article number: e17160703, Published: 17 AUG 2017
Brazilian Archives of Biology and Technology, Vol 60, Iss 0 (2017)
Brazilian Archives of Biology and Technology v.60 2017
Brazilian Archives of Biology and Technology
Instituto de Tecnologia do Paraná (Tecpar)
instacron:TECPAR
Brazilian Archives of Biology and Technology, Vol 60 (2017)
Acetaminophen (APAP) is a widely-used analgesic, while toxic doses of which induce liver injury. Inducible cyclooxygenase-2 (COX-2) is derived prostaglandins which play an anti-inflammatory role in acetaminophen-induced hepatotoxicity. Selective acti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28befc4a185af887ce741a2bc2648ffd
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132017000100427&lng=en&tlng=en
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6
Adverse cardiac responses to alpha-lipoic acid in a rat-diabetic model: possible mechanisms?
Autor: Hala A. Attia, Maha A. Al-Amin, Hanaa N. Al-Ajmi, Nawal M. Al-Rasheed, Nouf M. Al-Rasheed, Iman H. Hasan, Raeesa A. Mohamad
Publikováno v: Journal of Physiology and Biochemistry. 69:761-778
Alpha-lipoic acid (ALA) is widely used as an antioxidant for the treatment of diabetes and its complications; however, the pro-oxidant potential of ALA has recently been reported. This study was designed to investigate whether ALA supplementation cou
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccdae949125a257477979f6f01204463
https://doi.org/10.1007/s13105-013-0252-9
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7
Date fruits inhibit hepatocyte apoptosis and modulate the expression of hepatocyte growth factor, cytochrome P450 2E1 and heme oxygenase-1 in carbon tetrachloride-induced liver fibrosis
Autor: Nouf M. Al-Rasheed, Hala A. Attia, Nawal M. Al-Rasheed, Raeesa A. Mohamad, Maha A. Al-Amin, Musaed Al Fayez
Publikováno v: Archives of physiology and biochemistry. 123(2)
Context: Date fruits have protective effects against liver fibrosis; however their anti-apoptotic effects have not been investigated.Objective: To investigate the modulating effects of date fruits on pro- and anti-apoptotic markers, cytochrome P450 2
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14712a6c80004a968c1ef027d4ae71d6
https://pubmed.ncbi.nlm.nih.gov/27960551
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8
The antifibrotic and fibrolytic properties of date fruit extract via modulation of genotoxicity, tissue-inhibitor of metalloproteinases and nuclear factor- kappa B pathway in a rat model of hepatotoxicity
Autor: Hala A. Attia, Nawal M. Al-Rasheed, Raeesa A. Mohamad, Nouf M. Al-Rasheed, Maha A. Al-Amin
Publikováno v: BMC Complementary and Alternative Medicine
Background Hepatic fibrosis and its end point; cirrhosis, are the major cause of liver failure and death in patients with chronic liver disease. Therefore, the need for an effective treatment is evident. This study was designed to assess the potentia
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a62003a7d1748ab0d3896d898bc87240
http://europepmc.org/articles/PMC5078931
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9
Simvastatin prevents isoproterenol-induced cardiac hypertrophy through modulation of the JAK/STAT pathway
Autor: Nawal M. Al-Rasheed, Nouf M. Al-Rasheed, Reem Z Al-Manee, Maha M Al-Oteibi, Raeesa A. Mohamad, Sarah A Al-Shareef, Ayman M. Mahmoud, Iman H. Hasan
Publikováno v: Drug Design, Development and Therapy
Nouf M Al-Rasheed,1 Maha M Al-Oteibi,1 Reem Z Al-Manee,1 Sarah A Al-Shareef,1 Nawal M Al-Rasheed,1 Iman H Hasan,1 Raeesa A Mohamad,2 Ayman M Mahmoud3 1Department of Pharmacology, Faculty of Pharmacy, 2Department of Anatomy, College of Medicine, King
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f49ecdb2584b083f2a03772ecc805325
https://www.dovepress.com/simvastatin-prevents-isoproterenol-induced-cardiac-hypertrophy-through-peer-reviewed-article-DDDT
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