Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Raed S. Ismail"'
Autor:
Xiaoping Liu, Mohamed A. El-Mahdy, James Boslett, Saradhadevi Varadharaj, Craig Hemann, Tamer M. Abdelghany, Raed S. Ismail, Sean C. Little, Danlei Zhou, Le Thi Thanh Thuy, Norifumi Kawada, Jay L. Zweier
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
The gaseous signalling molecule nitric oxide regulates vascular tone. Here, the authors show that nitric oxide is degraded by the enzyme cytoglobin in the vascular wall, and that mice lacking cytoglobin have reduced blood pressure and are less sensit
Externí odkaz:
https://doaj.org/article/7c48b88ebe1f45628a4d604983c1bc11
Autor:
Abdelrahman M. Elsayed, Emine Bayraktar, Paola Amero, Salama A. Salama, Abdelaziz H. Abdelaziz, Raed S. Ismail, Xinna Zhang, Cristina Ivan, Anil K. Sood, Gabriel Lopez-Berestein, Cristian Rodriguez-Aguayo
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 1882 (2021)
Many long noncoding RNAs have been implicated in tumorigenesis and chemoresistance; however, the underlying mechanisms are not well understood. We investigated the role of PRKAR1B-AS2 long noncoding RNA in ovarian cancer (OC) and chemoresistance and
Externí odkaz:
https://doaj.org/article/8b34818cdf5a491293853d49a54bc5c5
Autor:
El-Sayed M. El-Sayed, Gouda K. Helal, Khalid S. Hassanien, Zakarya M. Zakarya, Raed S. Ismail
Publikováno v:
Journal of Clinical Pharmacy and Therapeutics. 46:942-949
WHAT IS KNOWN AND OBJECTIVE Sofosbuvir has been approved as the first nonstructural protein 5B polymerase inhibitor with pan-genotypic activity against the hepatitis C (HCV) virus. Daclatasvir is a first-in-class hepatitis C virus nonstructural prote
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 48:1024-1040
Pulmonary fibrosis is a devastating disease with unknown treatment. All-trans retinoic acid (ATRA) attenuates bleomycin-induced lung fibrosis by different mechanistic pathways. However, the role of retinoid receptors in lung fibrosis is still unclear
Publikováno v:
Acta Pharmaceutica, Vol 70, Iss 4, Pp 515-525 (2020)
Acta Pharmaceutica
Volume 70
Issue 4
Acta Pharmaceutica
Volume 70
Issue 4
Cisplatin-induced nephrotoxicity limits its anticancer effectiveness, thus this study’s aim was to assess the potential modulatory effect of perindopril on cisplatin-induced nephrotoxicity and to elucidate the possible underlying mechanisms. Renal
Autor:
Raed S. Ismail, Cristina Ivan, Gabriel Lopez-Berestein, Cristian Rodriguez-Aguayo, Emine Bayraktar, Abdelrahman M. Elsayed, Salama A. Salama, Xinna Zhang, Paola Amero, Abdel-Aziz H. Abdel-Aziz, Anil K. Sood
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 1882, p 1882 (2021)
Volume 22
Issue 4
International Journal of Molecular Sciences, Vol 22, Iss 1882, p 1882 (2021)
Volume 22
Issue 4
Many long noncoding RNAs have been implicated in tumorigenesis and chemoresistance
however, the underlying mechanisms are not well understood. We investigated the role of PRKAR1B-AS2 long noncoding RNA in ovarian cancer (OC) and chemoresistance
however, the underlying mechanisms are not well understood. We investigated the role of PRKAR1B-AS2 long noncoding RNA in ovarian cancer (OC) and chemoresistance
Publikováno v:
Toxicology. 457
We have addressed in the current study the potential of L-carnitine (LC) to extenuate the reproductive toxic insults of carbendazim (CBZ) in male rats, and the molecular mechanisms whereby carnitine would modify the spermatogenic and steroidogenic de
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 393(7)
The current study was designed to evaluate the potential abatement effect of pantoprazole against cisplatin-induced nephrotoxicity and establishing the possible protective mechanisms. Thirty-two male mice were allocated for treatment with saline, sin
Autor:
Fatma A. Mansoor, Raed S. Ismail, Tamer M. Abdelghany, Joseph R. Zweier, Frazer Lowe, Jay L. Zweier
Publikováno v:
Nitric Oxide. 76:113-121
Cigarette smoking (CS) is a well-established risk factor for cardiovascular disease (CVD). Endothelial dysfunction (ED) with loss of nitric oxide (NO) production is a central mechanism leading to the advent of CVD. Despite many prior studies of this
Autor:
Danlei Zhou, Sean C. Little, Jay L. Zweier, Craig Hemann, Norifumi Kawada, James Boslett, Mohamed A. El-Mahdy, Raed S. Ismail, Xiaoping Liu, Saradhadevi Varadharaj, Le Thi Thanh Thuy, Tamer M. Abdelghany
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature Communications
Nature Communications
The identity of the specific nitric oxide dioxygenase (NOD) that serves as the main in vivo regulator of O2-dependent NO degradation in smooth muscle remains elusive. Cytoglobin (Cygb) is a recently discovered globin expressed in fibroblasts and smoo