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of 3
pro vyhledávání: '"Raed B Saffarini"'
Autor:
James S Ruff, Raed B Saffarini, Leda L Ramoz, Linda C Morrison, Shambralyn Baker, Sean M Laverty, Petr Tvrdik, Mario R Capecchi, Wayne K Potts
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0174975 (2017)
Here we assess the fitness consequences of the replacement of the Hoxa1 coding region with its paralog Hoxb1 in mice (Mus musculus) residing in semi-natural enclosures. Previously, this Hoxa1B1 swap was reported as resulting in no discernible embryon
Externí odkaz:
https://doaj.org/article/23b571f354d54b03ac292e40dc4aadfe
Autor:
Shambralyn Baker, Sean M. Laverty, Wayne K. Potts, James S. Ruff, Raed B. Saffarini, Linda C. Morrison, Leda L. Ramoz, Petr Tvrdik, Mario R. Capecchi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 4, p e0174975 (2017)
PLoS ONE, Vol 12, Iss 4, p e0174975 (2017)
Here we assess the fitness consequences of the replacement of the Hoxa1 coding region with its paralog Hoxb1 in mice (Mus musculus) residing in semi-natural enclosures. Previously, this Hoxa1B1 swap was reported as resulting in no discernible embryon
Autor:
James S. Ruff, Sean M. Laverty, Petr Tvrdik, Linda C. Morrison, Shambralyn Baker, Raed B. Saffarini, Wayne K. Potts, Leda L. Ramoz
Publikováno v:
Genetics. 201(2)
Gene targeting techniques have led to the phenotypic characterization of numerous genes; however, many genes show minimal to no phenotypic consequences when disrupted, despite many having highly conserved sequences. The standard explanation for these