Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Raed Al‐Rajabi"'
Autor:
Ghassan K. Abou-Alfa, Tim Meyer, Richard Kinh Gian Do, Sarina A. Piha-Paul, Joseph S. Light, Scott Sherrin, Amin Yaqubie, Alison Clemens O’Neill, James J. Harding, Raed Al-Rajabi, Crystal S. Denlinger, Pablo Cano, Albert S. Cornelius, Eileen M. O'Reilly, Daniel DiPrimeo, Lisa D. Eli, John D. Gordan, David B. Solit
Publikováno v:
Liver Cancer, Pp 1-10 (2024)
Introduction: Fibrolamellar carcinoma (FLC) displays upregulation of several oncogenes, including HER2, and multiple immune-suppressive mechanisms. We investigated the efficacy and safety of the pan-HER tyrosine kinase inhibitor neratinib as monother
Externí odkaz:
https://doaj.org/article/060277f2d7054affa161c9c60698ca95
Autor:
Anwaar Saeed, Robin Park, Harsh Pathak, Ayah Nedal Al-Bzour, Junqiang Dai, Milind Phadnis, Raed Al-Rajabi, Anup Kasi, Joaquina Baranda, Weijing Sun, Stephen Williamson, Yu-Chiao Chiu, Hatice Ulku Osmanbeyoglu, Rashna Madan, Hassan Abushukair, Kelly Mulvaney, Andrew K. Godwin, Azhar Saeed
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract CAMILLA is a basket trial (NCT03539822) evaluating cabozantinib plus the ICI durvalumab in chemorefractory gastrointestinal cancer. Herein, are the phase II colorectal cohort results. 29 patients were evaluable. 100% had confirmed pMMR/MSS t
Externí odkaz:
https://doaj.org/article/ef214cc1e88d4bb382653082f8b6a181
Autor:
Weijing Sun, Nirmal Veeramachaneni, Raed Al‐Rajabi, Rashna Madan, Anup Kasi, Mazin Al‐Kasspooles, Joaquina Baranda, Anwaar Saeed, Milind A. Phadnis, Andrew K. Godwin, Mojtaba Olyaee, Natalie Streeter, Alykhan Nagji, Junqiang Dai, Stephen Williamson
Publikováno v:
Cancer Medicine, Vol 12, Iss 15, Pp 16098-16107 (2023)
Abstract Background Perioperative chemotherapy/chemoradiation is standard in esophageal/gastric/gastroesophageal junction (GEJ) adenocarcinoma, immune checkpoint inhibitors (ICI) effect in setting of metastatic and postoperatively. This study is to a
Externí odkaz:
https://doaj.org/article/613b6c3bdc634b1eace9ff580f7c8506
Autor:
Ian M. Freed, Anup Kasi, Oluwadamilola Fateru, Mengjia Hu, Phasin Gonzalez, Nyla Weatherington, Harsh Pathak, Stephen Hyter, Weijing Sun, Raed Al-Rajabi, Joaquina Baranda, Mateusz L. Hupert, Prabhakar Chalise, Andrew K. Godwin, Malgorzata A. Witek, Steven A. Soper
Publikováno v:
Cells, Vol 12, Iss 18, p 2266 (2023)
There is a high clinical unmet need to improve outcomes for pancreatic ductal adenocarcinoma (PDAC) patients, either with the discovery of new therapies or biomarkers that can track response to treatment more efficiently than imaging. We report an in
Externí odkaz:
https://doaj.org/article/9fecc40105aa4e958c30860a3c5755e3
Autor:
Ghulam Rehman Mohyuddin, Muhammad Aziz, Alec Britt, Lee Wade, Weijing Sun, Joaquina Baranda, Raed Al-Rajabi, Anwaar Saeed, Anup Kasi
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-9 (2020)
Abstract Background PARP inhibitors (PARPi) have recently been approved for various malignancies based on the results of several clinical trials. However, these trials have mostly recruited patients with germline BRCA mutations, and it is unclear whe
Externí odkaz:
https://doaj.org/article/866273a944434fd5ad321569c2fb5010
Autor:
David Standing, Levi Arnold, Prasad Dandawate, Brendan Ottemann, Vusala Snyder, Sivapriya Ponnurangam, Afreen Sayed, Dharmalingam Subramaniam, Pugazhendhi Srinivasan, Sonali Choudhury, Jacob New, Deep Kwatra, Prabhu Ramamoorthy, Badal C. Roy, Melissa Shadoin, Raed Al‐Rajabi, Maura O'Neil, Sumedha Gunewardena, John Ashcraft, Shahid Umar, Scott J. Weir, Ossama Tawfik, Subhash B. Padhye, Bernhard Biersack, Shrikant Anant, Sufi Mary Thomas
Publikováno v:
Molecular Carcinogenesis. 62:145-159
Doublecortin like kinase 1 (DCLK1) plays a crucial role in several cancers including colon and pancreatic adenocarcinomas. However, its role in squamous cell carcinoma (SCC) remains unknown. To this end, we examined DCLK1 expression in head and neck
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd9a55de8758a49d33e008a5ba3586e
https://doi.org/10.1002/mc.23472
https://doi.org/10.1002/mc.23472
Autor:
Anup Kasi, Pramod Gaudel, Manidhar Lekkala, Raed Al-Rajabi, Anwaar Saeed, Weijing Sun, Charles Porter
Publikováno v:
Journal of Oncology Pharmacy Practice. :107815522311618
Introduction Fluoropyrimidines (FP) are cornerstone drugs in the treatment of gastrointestinal (GI) malignancies. Cardiotoxicity secondary to an FP chemotherapy is a serious complication. There are no standardized guidelines on the treatment of FP in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::259443d0d0c1f1a71c85345cd77ebe25
https://doi.org/10.1177/10781552231161822
https://doi.org/10.1177/10781552231161822
Autor:
Hassan Hatoum, Charles J. Link, Nicholas N. Vahanian, Noelle K. LoConte, Lodovico Balducci, Gabriela R. Rossi, Raed Al-Rajabi, John Seng, Eugene P. Kennedy, Nicholas Nissen, Joshua Banks, Warren S. Brenner, Thomas J. George, Benjamin L. Musher, Emad Elquza, Harish Lavu, Charles J. Yeo, Benjamin E. Leiby, Andrew L. Coveler, Gina M. Vaccaro, D Brock Hewitt
Publikováno v:
Hepatobiliary Surg Nutr
Objectives To compare the efficacy and safety of algenpantucel-L (HAPa; IND# 12311) immunotherapy combined with standard of care (SOC) chemotherapy and chemoradiation to SOC chemotherapy and chemoradiation therapy alone in patients with borderline re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a242a9659f405faa3d0bf5072d91ac2
https://doi.org/10.1097/sla.0000000000004669
https://doi.org/10.1097/sla.0000000000004669
Autor:
Joaquina Baranda, Weijing Sun, Lee Wade, Anwaar Saeed, Alec Britt, Muhammad Aziz, Raed Al-Rajabi, Ghulam Rehman Mohyuddin, Anup Kasi
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-9 (2020)
BMC Cancer
BASE-Bielefeld Academic Search Engine
BMC Cancer
BASE-Bielefeld Academic Search Engine
BackgroundPARP inhibitors (PARPi) have recently been approved for various malignancies based on the results of several clinical trials. However, these trials have mostly recruited patients with germline BRCA mutations, and it is unclear whether PARPi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b5e6944ad37e71dfec0d867e5878bc
http://link.springer.com/article/10.1186/s12885-020-06948-5
http://link.springer.com/article/10.1186/s12885-020-06948-5
Autor:
Anwaar Saeed, Robin Park, Junqiang Dai, Raed Al-Rajabi, Anup Kasi, Joaquina Baranda, Stephen Williamson, Azhar Saeed, Jacob Ripp, Zachary Collins, Kelly Mulvaney, Molly Shugrue, Jeanette Firth-Braun, Shrikant Anant, Andrew K. Godwin, Rashna Madan, Milind Phadnis, Weijing Sun
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b8930681affc8b8339d515d31629f72
https://doi.org/10.2139/ssrn.4195069
https://doi.org/10.2139/ssrn.4195069