Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Raed Abu Dawud"'
Autor:
Mona Elsafadi, Muthurangan Manikandan, Nehad M Alajez, Rimi Hamam, Raed Abu Dawud, Abdullah Aldahmash, Zafar Iqbal, Musaad Alfayez, Moustapha Kassem, Amer Mahmood
Publikováno v:
Stem Cell Research, Vol 20, Iss C, Pp 94-104 (2017)
Understanding the regulatory networks underlying lineage differentiation and fate determination of human bone marrow stromal cells (hBMSC) is a prerequisite for their therapeutic use. The goal of the current study was to unravel the novel role of the
Externí odkaz:
https://doaj.org/article/5ec004bc5b244b1ebb0e5388c63da19a
Autor:
Mona Elsafadi, Muthurangan Manikandan, Sami Almalki, Mohammad Mobarak, Muhammad Atteya, Zafar Iqbal, Jamil Amjad Hashmi, Sameerah Shaheen, Nehad Alajez, Musaad Alfayez, Moustapha Kassem, Raed Abu Dawud, Amer Mahmood
Publikováno v:
Stem Cells International, Vol 2018 (2018)
TGFβ is a potent regulator of several biological functions in many cell types, but its role in the differentiation of human bone marrow-derived skeletal stem cells (hMSCs) is currently poorly understood. In the present study, we demonstrate that a s
Externí odkaz:
https://doaj.org/article/754a329fbe56448992eeed4d0091ca32
Autor:
Linda Harkness, Natalie A. Twine, Raed Abu Dawud, Abbas Jafari, Abdullah Aldahmash, Marc R. Wilkins, James Adjaye, Moustapha Kassem
Publikováno v:
Bone Reports, Vol 3, Iss C, Pp 32-39 (2015)
Human bone marrow-derived stromal (skeletal) stem cells (BM-hMSC) are being employed in an increasing number of clinical trials for tissue regeneration. A limiting factor for their clinical use is the inability to obtain sufficient cell numbers. Huma
Externí odkaz:
https://doaj.org/article/ec7413f0d75645499381d1a54b67b310
Autor:
Basem M. Abdallah, Asma Al-Shammary, Peter Skagen, Raed Abu Dawud, James Adjaye, Abdullah Aldahmash, Moustapha Kassem
Publikováno v:
Stem Cell Research, Vol 15, Iss 3, Pp 449-458 (2015)
Bone marrow stromal cells (BMSCs, also known as bone marrow-derived mesenchymal stem cells) and their progenitors have been identified based on retrospective functional criteria. CD markers are employed to define cell populations with distinct functi
Externí odkaz:
https://doaj.org/article/8baad275732a4d389f581769d0ac4b12
Publikováno v:
EBioMedicine, Vol 110, Iss , Pp 105451- (2024)
Summary: The circadian clock, a fundamental cellular mechanism, regulates the rhythmic expression of numerous genes and biological processes across various organs. Disruptions in this system, driven by genetic or environmental factors, have been repo
Externí odkaz:
https://doaj.org/article/250b6ee6d621477d8c8e4818e1ecf8e5
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39896 (2012)
While human embryonic stem cells (hESCs) and human embryonal carcinoma cells (hECCs) have been studied extensively at the levels of the genome, transcriptome, proteome and epigenome our knowledge of their corresponding metabolomes is limited. Here, w
Externí odkaz:
https://doaj.org/article/22b33fe94ad44767833027e2b0709ca1
Autor:
Junaid Kashir, Bhavesh V. Mistry, Lujain BuSaleh, Michail Nomikos, Sarah Almuqayyil, Raed Abu-Dawud, Nadya AlYacoub, Hamdan Hamdan, Saad AlHassan, F. Anthony Lai, Abdullah M. Assiri, Serdar Coskun
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 198 (2023)
Mammalian oocyte activation is initiated by intracellular calcium (Ca2+) oscillations, driven by the testis-specific phospholipase C zeta (PLCζ). Sperm PLCζ analysis represents a diagnostic measure of sperm fertilisation capacity. The application o
Externí odkaz:
https://doaj.org/article/a4ab80c5fba549ef92f4b8173307b327
Autor:
Raed, Abu-Dawud, Bhavesh V, Mistry, Mohamed, Rajab, Maha, Alanazi, Nadya, Al-Yacoub, Junaid, Kashir, Falah, Almohanna, Dilek, Colak, Abdullah M, Assiri
Publikováno v:
Scientific Reports. 12
During mammalian spermatogenesis, the ubiquitin proteasome system maintains protein homoeostasis (proteastasis) and spermatogenic cellular functions. DCAF17 is a substrate receptor in the ubiquitin CRL4 E3 Ligase complex, absence of which causes olig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15b9d84729b20488f82f6ef7059c339b
https://doi.org/10.1038/s41598-022-25826-7
https://doi.org/10.1038/s41598-022-25826-7
Autor:
Raed Abu-Dawud, MahaAdel Gumssani, BhaveshV Mistry, Reema B. Abu-Dawas, Kevin Coward, AbdullahM Assiri, FAnthony Lai, Muhammad Rajab, Celine Jones, Nadya Al-Yacoub, Junaid Kashir, Falah Al-Mohanna, Michail Nomikos
Publikováno v:
Asian Journal of Andrology
Asian Journal of Andrology, Vol 23, Iss 2, Pp 178-187 (2021)
Asian Journal of Andrology, Vol 23, Iss 2, Pp 178-187 (2021)
Sperm-specific phospholipase C zeta (PLCζ) initiates intracellular calcium (Ca2+) transients which drive a series of concurrent events collectively termed oocyte activation. Numerous investigations have linked abrogation and absence/reduction of PLC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef649c214b3c699e6dceeb0f6075aa30
http://europepmc.org/articles/PMC7991809
http://europepmc.org/articles/PMC7991809
Autor:
Raed Abu-Dawud, Bhavesh V. Mistry, Renad Almahdali, Maryam M. Matin, Ayodele Alaiya, Fatimah Alghamdi, Hala Alamari, Nadya Al-Yacoub, Junaid Kashir, Marwa Houssein, Abdullah Alawad, Peter W. Andrews, Abdullah M. Assiri
Publikováno v:
Tissue and Cell. 78:101893
DPPA4 is essential for the pluripotent stem cell state, yet its function is poorly understood. DPPA4 is localized in the nucleus, where it is associated with active chromatin. We now report that it is also present in the cytosol, where it appears as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83d804a404d21352221ae62587e46933
https://doi.org/10.1016/j.tice.2022.101893
https://doi.org/10.1016/j.tice.2022.101893